Laura Weisbein

ORCID: 0009-0000-2303-579X
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • COVID-19 and healthcare impacts
  • Eosinophilic Esophagitis
  • Colorectal Cancer Screening and Detection
  • COVID-19 Clinical Research Studies
  • Gastrointestinal motility and disorders
  • Healthcare Policy and Management
  • Nursing Roles and Practices
  • Empathy and Medical Education
  • Systemic Lupus Erythematosus Research
  • SARS-CoV-2 and COVID-19 Research
  • Innovations in Medical Education
  • Sleep and related disorders
  • Primary Care and Health Outcomes
  • Clinical Nutrition and Gastroenterology
  • Vaccine Coverage and Hesitancy
  • Helicobacter pylori-related gastroenterology studies
  • Lymphoma Diagnosis and Treatment
  • Diagnosis and treatment of tuberculosis
  • Pancreatitis Pathology and Treatment

University of North Carolina at Chapel Hill
2020-2023

University of North Carolina Health Care
2022

Patients with inflammatory bowel disease (IBD) may be at risk for complications due to the COVID-19 pandemic. We performed a qualitative study better understand IBD patient experiences and concerns when navigating pandemic, goal of prioritizing patients' information needs.We conducted series semistructured virtual focus groups 6 months, then member checking 1 year into included questions on pandemic IBD, differences in their experience as compared peers, fears, well preferred sources....

10.1093/crocol/otab066 article EN cc-by Crohn s & Colitis 360 2021-09-15

Patients with inflammatory bowel disease (IBD) are at increased risk of infections, bone fractures, and skin cancers.We developed preventive health videos using a patient-centered approach tested their impact on uptake.Five animated explaining recommendations in IBD were iteratively focus groups interviews. A randomized controlled trial was then conducted web-based cohort to test the video- versus text-based educational interventions. The primary outcome receipt influenza vaccine. Secondary...

10.2196/42921 article EN cc-by Journal of Medical Internet Research 2023-03-23

<title>Abstract</title> REM Sleep Behavior Disorder (RBD) and Inflammatory Bowel Disease (IBD) are associated with Parkinson’s Disease. We hypothesized that RBD prevalence is greater in IBD than controls. 158 controls 462 patients completed IBD-related history questionnaires the Single-Question Screen (RBD1Q) RBD-Screening Questionnaire assessing RBD. was compared using chi-squared testing. Logistic regression explored factors (RBD1Q), adjusting for age, sex, race. higher (14.1% vs. 5.1%; p...

10.21203/rs.3.rs-5356372/v1 preprint EN cc-by Research Square (Research Square) 2024-11-13

Abstract Background Primary and secondary non-response to Anti-Tumor Necrosis Factor (TNF) therapy is common in patients with ulcerative colitis (UC), yet limited research has compared the effectiveness of subsequent biological therapy. Objective We sought compare vedolizumab tofacitinib anti-TNF experienced UC, focusing on patient-prioritized patient reported outcomes (PROs). Methods conducted a prospective cohort study nested within Crohn’s &amp; Colitis Foundation’s IBD Partners SPARC...

10.1093/crocol/otad031 article EN cc-by-nc Crohn s & Colitis 360 2023-05-29

Patients with inflammatory bowel disease (IBD) may be at risk for development of COVID-19 infection due to innate immune dysfunction and/or immunosuppressive medication use.

10.1093/crocol/otac011 article EN cc-by Crohn s & Colitis 360 2022-03-28

INTRODUCTION: Patients with inflammatory bowel disease (IBD) are at increased risk of infections, bone fractures and skin cancers. Preventive efforts may reduce the these complications. Using an iterative patient-centered approach, we developed dynamic preventive health videos tested impact videos, compared to static text-based interventions, on uptake in patients IBD. METHODS: Consecutive adults IBD enrolled Partners cohort were a randomized controlled trial (video) vs. (text) educational...

10.14309/01.ajg.0000704724.40016.77 article EN The American Journal of Gastroenterology 2020-10-01

Abstract Background Patients with inflammatory bowel disease (IBD) may be at risk for development of COVID-19 infection due to innate immune dysfunction and/or immunosuppressive medication use. We sought 1) evaluate the incidence in a large, U.S. cohort patients IBD and 2) associations between demographic, clinical, treatment-related factors infection. Methods Participants 3 adult studies sponsored by Crohn’s &amp; Colitis Foundation, Partners, QORUS (Improving Quality Care Adults...

10.1093/ecco-jcc/jjab232.760 article EN Journal of Crohn s and Colitis 2022-01-01

Introduction: In patients with ulcerative colitis (UC), clinical trials often focus on disease activity measures such as rectal bleeding and stool frequency. Patients UC frequently experience bowel urgency (BU), yet less is known about the prevalence of BU its association quality life (QoL) in real-world population. Methods: this cross-sectional study from nationwide inflammatory (IBD) Partners cohort, was measured utilizing validated 11-point Urgency Numeric Rating Scale (NRS)1. Scores were...

10.14309/01.ajg.0000953700.12211.dc article EN The American Journal of Gastroenterology 2023-10-01

Introduction: In patients with Crohn’s disease (CD), clinical trials often focus on activity measures such as abdominal pain and stool frequency. Patients CD frequently experience bowel urgency (BU), yet less is known about the prevalence of BU its association quality life (QoL) in real-world populations. Methods: this cross-sectional study from nationwide inflammatory (IBD) Partners cohort, was measured utilizing validated 11-point Urgency Numeric Rating Scale (NRS)1. This categorized into...

10.14309/01.ajg.0000953704.69921.6d article EN The American Journal of Gastroenterology 2023-10-01

Background: Dietary factors and possible dietary interventions that may affect inflammatory bowel disease (IBD) course are of great interest. Several epidemiologic studies show a correlation between patterns the risk developing IBD, but data regarding specific components, their effect on in established IBD still lacking. Some have shown fat intake ulcerative colitis (UC), not Crohn’s (CD). We aimed to study association consumption items high saturated flare. Methods: The for this were...

10.14309/01.ajg.0000995988.33419.a7 article EN The American Journal of Gastroenterology 2023-12-01

INTRODUCTION: Patients with inflammatory bowel disease (IBD) are at increased risk for acquiring and having worse outcomes vaccine-preventable infections such as influenza, bacterial pneumonia, herpes zoster. Additionally, they skin cancer, many have factors osteoporosis. Vaccines, annual checks, bone health screening recommended people IBD, but uptake of these recommendations remains low. The aim this study was to develop a series short videos using patient-centered approach raise awareness...

10.14309/01.ajg.0000705648.67089.71 article EN The American Journal of Gastroenterology 2020-10-01

<sec> <title>BACKGROUND</title> Patients with inflammatory bowel disease (IBD) are at increased risk of infections, bone fractures, and skin cancers. </sec> <title>OBJECTIVE</title> We developed preventive health videos using a patient-centered approach tested their impact on uptake. <title>METHODS</title> Five animated explaining recommendations in IBD were iteratively focus groups interviews. A randomized controlled trial was then conducted web-based cohort to test the video- versus...

10.2196/preprints.42921 preprint EN 2022-10-07

Introduction: Primary and secondary non-response to anti-TNF therapy is common in patients with Crohn’s disease (CD), yet there a paucity of research comparing vedolizumab ustekinumab as subsequent therapy. Prior studies, limited tertiary care centers Europe, have yielded conflicting results did not include reported outcomes (PROs). We sought compare the effectiveness experienced CD, focusing on patient-prioritized PROs. Methods: utilized IBD Partners internet-based infrastructure conduct...

10.14309/01.ajg.0000860376.18652.65 article EN The American Journal of Gastroenterology 2022-10-01
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