A5066587262- Alzheimer's disease research and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Mitochondrial Function and Pathology
University of Sheffield
2023-2024
Abstract Background Astrocytes have multiple roles including providing neurons with metabolic substrates and maintaining neurotransmitter synaptic homeostasis. Astrocyte glucose metabolism plays a key role in learning memory astrocytic glycogen substrate supporting encoding. The neuronal support provided by astrocytes has high demand. Deficits mitochondrial functioning glycolysis could impair function. Changes to cellular are seen early Alzheimer’s disease (AD). Understanding changes AD be...
Abstract Background Astrocytes have multiple roles including providing neurons with metabolic substrates and maintaining neurotransmitters at neuronal synapses. Astrocyte glucose metabolism plays a key role in learning memory astrocytic glycogen substrate supporting encoding. The homeostatic the astrocyte provides for leads to demands, meaning that abnormalities function of mitochondria glycolysis could affect this relationship. Changes cellular are seen early Alzheimer’s disease (AD)....