A5041470021- Renal Diseases and Glomerulopathies
- Cholesterol and Lipid Metabolism
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Drug Transport and Resistance Mechanisms
- Systemic Lupus Erythematosus Research
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- Glioma Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Head and Neck Surgical Oncology
- Intensive Care Unit Cognitive Disorders
- Immune cells in cancer
- Liver Disease Diagnosis and Treatment
- S100 Proteins and Annexins
- Cancer Immunotherapy and Biomarkers
- Respiratory viral infections research
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
Laboratoire de Biochimie
2023-2025
Université de Toulouse
2025
Université Toulouse III - Paul Sabatier
2025
Centre Hospitalier Universitaire de Toulouse
2021-2023
Laboratoire de Biochimie
2023
Hôpital Purpan
2022
Acute interstitial nephritis (AIN) is the most common renal immune-related adverse event after immune check-point inhibitors (ICI). We hypothesized that alternatively activated macrophages (CD163-M) could be involved in ICI-AIN and wished to evaluate use of their soluble urinary form (us)CD163 as a non-invasive diagnostic marker. CD163-M infiltrates were evaluated by both immune-histochemistry multiplex immunofluorescence imaging. usCD163 was detected with ELLA technology together creatinine...
The present study aimed to determine whether current commercial immunoassays are adequate for detecting anti-Omicron antibodies. We analyzed the anti-SARS-CoV-2 antibody response of 23 unvaccinated individuals 1-2 months after an Omicron infection. All blood samples were tested with a live virus neutralization assay using clinical BA.1 strain and four SARS-CoV-2 immunoassays. assessed three anti-Spike (SARS-CoV-2 IgG II Quant [Abbott S], Wantaï ELISA [Wantaï], Elecsys Anti-SARS-CoV-2 S...
Lupus nephritis (LN) diagnosis and follow-up requires noninvasive biomarkers. Therefore, the added value of coupling urinary soluble (s)CD163/creatinuria ratio with serological markers was evaluated in a real-world clinical practice. To this end, monocentric retrospective study conducted 139 SLE patients biopsy-proven having an active LN (LN-A, n = 63 positive SLEDAI-renal score) or inactive (n 76), as well 98 non-renal patients. The sCD163/creatinuria outperformed for predicting LN-A...
Craniopharyngioma is a rare condition in children, but it the most frequent tumor that occurs hypothalamic pituitary region. Chemical meningitis has been described as an uncommon postoperative complication, no chemical due to spontaneous rupture leading craniopharyngioma diagnosis children reported.This case of 13-year-old boy presenting with fever, vomiting and headache for two days. The CT scan revealed suprasellar lesion, lumbar puncture showed aseptic meningitis. cerebral MRI suggested...
A 20-year-old Caucasian woman was referred to the internal medicine department for investigation of unexplained chronic haemolytic anaemia (haemoglobin: 100 g/L) with negative direct anti-globulin test, thrombocytopaenia (102 × 109/L) and xanthelasma palpebrarum (Figure 1A). Clinical examination showed mild splenomegaly. Blood film 1B, May-Grünwald-Giemsa, original magnification ×100) revealed marked stomatocytosis large platelets. Plasma cholesterol triglyceride levels were normal but plant...