A5011829596- Neuroinflammation and Neurodegeneration Mechanisms
- Autophagy in Disease and Therapy
- Tryptophan and brain disorders
- Phytochemistry and biological activity of medicinal plants
- Pharmacological Effects of Natural Compounds
- Dermatology and Skin Diseases
- Reproductive System and Pregnancy
- Medicinal Plants and Bioactive Compounds
- Ferroptosis and cancer prognosis
- Reproductive tract infections research
- Sirtuins and Resveratrol in Medicine
- Hops Chemistry and Applications
- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Cancer-related molecular mechanisms research
- Extracellular vesicles in disease
- Machine Learning and ELM
- RNA modifications and cancer
- Stress Responses and Cortisol
- MicroRNA in disease regulation
Guangzhou University of Chinese Medicine
2021-2025
Introduction: Breast cancer (BC) is the leading female malignancy, with one million new cases diagnosed worldwide per year. However, current treatment options for BC patients have difficulty achieving satisfactory efficacy. Ferroptosis a mode of regulated cell death that plays key role in inhibition tumorigenesis. Levistilide A (LA), as an active compound extracted from Chuanxiong Rhizoma, might prevent development tumors by regulating critical cellular processes ferroptosis. Methods: In...
Previous studies reported that emodin extracted from Rheum palmatum L. exerts antiproliferation and antimetastatic effects in a variety of human cancer types. However, the role hepatocellular carcinoma (HCC) remain unknown.EdU colony formation assays were performed to evaluate on proliferation. The mobility capacities HCC treated with evaluated using wound healing assay. Transwell invasion migration anti-migratory anti-invasive HCC. Annexin V-FITC/PI was analyze apoptosis. PI stain cell...
Traditional Chinese medicine formula Kai-Xin-San (KXS) is used to treat psychiatric disorders, especially in anxiety and depression. However, the precise molecular mechanism of action remains unclear. In this study, we investigated antidepressant effect KXS on inhibiting inflammation oxidative stress corticosterone (CORT)-induced depression.The therapeutic efficacy was evaluated a mouse model depression induced by CORT. Behavioral tests were conducted evaluate effectiveness treating...
Endometriosis (EMs) is characterized by ectopic growth of active endometrial tissue outside the uterus. The Luoshi Neiyi prescription (LSNYP) has been extensively used for treating EMs in China. However, data on chemical components LSNYP are insufficient, and its pharmacological mechanism treatment remains unclear. This study aimed to explore potential through network pharmacology based absorbed into blood. Ultra-high performance liquid chromatography-quadrupole time-of-flight mass...
Abstract Background: Previous studies reported that emodin extracted from Rheum palmatum L. exerts antiproliferation and anti metastatic effects in a variety of human cancer types. However, the role hepatocellular carcinoma (HCC) remain unknown. Methods: EdU colony formation assays were performed to evaluate on proliferation. The mobility capacities HCC treated with evaluated using wound healing assay. T ranswell invasion migration anti-migratory anti-invasive HCC. Annexin V-FITC/PI was...