A5098695711- Extracellular vesicles in disease
- Nanopore and Nanochannel Transport Studies
- Solar-Powered Water Purification Methods
- Nanoplatforms for cancer theranostics
- RNA Interference and Gene Delivery
- Dendrimers and Hyperbranched Polymers
- MicroRNA in disease regulation
École Nationale Supérieure de Chimie de Montpellier
2024
Université de Montpellier
2024
Centre National de la Recherche Scientifique
2024
Extracellular vesicles (EVs) are non-replicative, cell-derived membranous structures secreted by potentially all eukaryotic cells, playing a crucial role in intercellular communication. The study of EVs requires approaches and tools, which have predominantly been developed for mammalian models. Here, we undertook multimodal characterization mosquito to provide technical knowledge foundation their study. First, using cell line model from Aedes aegypti applying multiple analytical technologies...
Although, extracellular vesicles (EVs) appear as future promising therapeutics, their in vivo instability after administration remains an important barrier to development. While many groups have evaluated EV surface modification strategies add a targeting group control biodistribution, far fewer focused on stabilization obtain "stealth" allogenic EVs. This aspect is fundamental prerequisite for development nano therapeutics. Here, we explored lipid anchorage the membrane of PEG alternative,...
Abstract Despite biomolecule delivery is a natural function of Extracellular Vesicles (EVs), loading exogenous macromolecules such as proteins into EVs remains major challenge limiting their interest convincing protein systems for health applications. In this context, lipid-anchorage cargo EV membrane recently emerged promising option to enable vectorization cells. Nevertheless, was not explored intracellular delivery, and further characterization the critical parameters governing...