- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Advanced biosensing and bioanalysis techniques
- Medicinal plant effects and applications
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Seaweed-derived Bioactive Compounds
- RNA Interference and Gene Delivery
- Moringa oleifera research and applications
- Race, History, and American Society
- Lipid Membrane Structure and Behavior
- Food Industry and Aquatic Biology
- Sphingolipid Metabolism and Signaling
- Selenium in Biological Systems
- Animal Nutrition and Physiology
- Biocrusts and Microbial Ecology
- Blood properties and coagulation
- Marine Sponges and Natural Products
- Postcolonial and Cultural Literary Studies
- Tryptophan and brain disorders
- Allelopathy and phytotoxic interactions
- Phytochemical and Pharmacological Studies
- Microbial Metabolites in Food Biotechnology
- Microbial Inactivation Methods
- Fibroblast Growth Factor Research
Wuhan Polytechnic University
2023-2025
Wuhan Blood Center
2023-2024
Shihezi University
2024
Huazhong University of Science and Technology
2023-2024
Chinese PLA General Hospital
2024
Guangdong Pharmaceutical University
2024
Ruijin Hospital
2024
Xinjiang Academy of Agricultural Sciences
2023
Institute of Applied Technology
2014
First Bethune Hospital of Jilin University
1991-2000
Bitter melon seed oil (BMSO), as a by-product of bitter gourd fruit processing, is rich in active ingredients and has unique medicinal potential. However, its solubility dispersibility water are poor when used directly. Therefore, this study aims to develop an eco-friendly submicron emulsion containing BMSO for intravenous injection evaluate safety. The (BMSOSE) was prepared by high-pressure homogenization. size, polydispersity index (PDI), ζ-potential, Turbiscan stability (TSI), apparent...
Bone-fat balance is crucial to maintain bone homeostasis.As common progenitor cells of osteoblasts and adipocytes, marrow mesenchymal stem (BMSCs) are delicately balanced for their differentiation commitment.However, the exact mechanisms governing BMSC cell fate unclear.In this study, we discovered that fibroblast growth factor 9 (Fgf9), a cytokine expressed in niche, controlled bone-fat by influencing BMSCs.Histomorphology cytodifferentiation analysis showed Fgf9 loss-of-function mutation...
Super-resolution fluorescence microscopy has emerged as a powerful tool for studying endoplasmic reticulum (ER) dynamics in living cells. However, the lack of high-brightness, high-photostability, and stable labeling probes makes long-term super-resolution imaging ER still challenging. Herein, we reported surface-functionalized Halo-tag gold nanofluorescent probe (GNP-Atto565-fR8-CA) that exhibits excellent brightness, photostability, biocompatibility. GNP-Atto565-fR8-CA can simultaneously...
Solid beverages of effervescent tablets have good taste and portable features are favored by consumers, but product quality nutrition cannot meet the need increasing nutritional requirements. Sea buckthorn fruit has a special flavor nutrient-rich characteristics, related products not been developed. In this paper, different additive contents (sea powder, erythritol, disintegrant, maltodextrin, polyvinylpyrrolidone (PVP)) were optimized using random centroid method; obtained effect sensory...
Journal Article Antitumor Activity of Some Polysaccharides Isolated from a Chinese Mushroom, “Huangmo”, the Fruiting Body Hohenbuehelia serotina Get access Yan Ma, Ma Faculty Basic Medical Science, Norman Bethune University Sciences, Changchun, Jilin, China Search for other works by this author on: Oxford Academic Google Scholar Takashi Mizino, Mizino ChinaFaculty Agriculture, Shizuoka University, Ohya, 422, Japan To whom all correspondence should be addressed. Hitoshi Ito School Medicine,...
Polysaccharides were extracted from a Chinese mushroom, "Huangmo" with hot water (FI), 1% ammonium oxalate solution (FII), and 5% sodium hydroxide (FIII) 20 more polysaccharides isolated by ethanol precipitation, ion-exchange chromatography, gel filtration, affinity chromatography. Of the six obtained, FI0, FA-1, FA-2, FII-2, FIII-1-b, FIII-2-b selected on basis of results antitumor activity test (the Sarcoma 180/mice, i.p. method). Six fractions which showed relatively high activities...
Acute ischemic stroke (AIS) is the second leading cause of death worldwide. This study aims at assessing platelet morphology, ultrastructure and function changes platelets in acute patients by technique Structured Illumination Microscopy (SIM). assay collected platelet-rich plasma (PRP) from 11 AIS 12 healthy controls. Each PRP sample was divided into 7 groups:1) rest group; 2) Thrombin-treated 5 min 3) Thrombin plus 2MeSAMP-treated 4) Aspirin-treated 5) 1 h 6) 7) group. SIM applied to...
Vesicle entrapment remains a major bottleneck for the application of fluorescent nanoprobes (FNPs) with excellent optical properties in field super-resolution imaging subcellular structures living cells. Here, we developed cell-penetrating peptide, fR8, which enables efficient cytoplasmic delivery 3.5 nm FNPs instead being trapped vesicles, efficiency up to 75.6%. Further, have successfully combined fusion protein technology FNPs-fR8 achieve high specificity and stable labeling various...
This study aimed to explore the impact of Brassica rapa L. polysaccharides (BRP) on growth, immune response, antioxidant capacity, and cecal microbiota in yellow-feathered quails. A total 250 one-day-old quails, evenly divided by sex, were randomly assigned five groups, with each group comprising ten replicates quails each. The control (CON) received a basic diet, while antibiotic (CTC) was fed diet supplemented chlortetracycline (0.05 g/kg). BRP administered at concentrations 0.25 g/kg (Low...
Several compounds were isolated from a Chinese mushroom, Huangmo, the heat-dried fruiting body of Hohenbuehelia serotina. They identified as linoleic acid (I), hexadecanoic (II), β-sitosterol (IV), benzoic (V), D-mannitol (VI), sucrose (VII), and L-rhamnose (VIII). In addition, six acidic substances identified. (Table I). Also, ethyl linoleate, acid, 9,12-octadecadienoic (Z-Z) esters, IV, V, VI for first time this mushroom.
How to rebuild black women's identity and dignity under the multiple oppression of classism, sexism racism has always been Toni Morrison's major concern.The paper analyzes three solutions problem crisis in her first novel The Bluest Eye.Loving one's image, loving family culture are essential ways.By doing so can women retain their authentic identities.
Abstract Inhibitors against the bromodomain and extra terminal domain (BET) family of proteins have been pursued as promising oncology agents based on growing understanding epigenetic control disease processes. Through scaffold-based crystallography-guided drug design, we discovered PLX51107, a potent selective small molecule inhibitor BET bromodomains. PLX51107 is structurally unrelated to benzodiazepines such JQ1, I-BET762, OTX015 other published inhibitors. exhibits low nanomolar potency...
Because of their excellent photostability and brightness, organic fluorophores are becoming increasingly attractive for long-term live-cell superresolution imaging subcellular structures but often suffer from low cell permeability. Here, we develop a general strategy to deliver cell-impermeable fluorescent probes, including various SNAP/Halo tag into live cells with delivery efficiency (up 97% labeling) almost 100% endo/lysosomal release by simple coincubation novel type peptide vehicle,...
(1995). Huangmo, Ohma, Hohenbuehelia serotina: Antitumor polysaccharides. Food Reviews International: Vol. 11, Mushrooms: The Versatile Fungus-Food and Medicinal Properties, pp. 189-192.