- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Global Health Care Issues
- Platelet Disorders and Treatments
- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Medical Imaging Techniques and Applications
- Climate Change and Health Impacts
- HIV, Drug Use, Sexual Risk
- Maternal Mental Health During Pregnancy and Postpartum
- Nuclear Receptors and Signaling
- Blood properties and coagulation
- Stroke Rehabilitation and Recovery
- Environmental Quality and Pollution
- Potassium and Related Disorders
- Medical Imaging and Analysis
- Bioeconomy and Sustainability Development
- Bone Metabolism and Diseases
- Natural Compounds in Disease Treatment
- Healthcare Systems and Reforms
- Land Rights and Reforms
- Epilepsy research and treatment
- Blood groups and transfusion
- Optimism, Hope, and Well-being
- Food Waste Reduction and Sustainability
Central Hospital of Wuhan
2024
Sichuan University
2017-2024
West China Hospital of Sichuan University
2024
Huazhong University of Science and Technology
2018-2024
South China Agricultural University
2024
Hubei Provincial Hospital of Traditional Chinese Medicine
2021-2022
Wuhan Puai Hospital
2018-2022
Union Hospital
2022
Hubei University of Chinese Medicine
2021
First Hospital of China Medical University
2020
Although antibiotics are generally well tolerated, their toxic effects on the central nervous system have been gained attention. In this study, we systematically investigated neuron toxicity of from six different classes. We show that clinically relevant concentrations metronidazole, tigecycline, azithromycin and clindamycin but not ampicillin or sulfamethoxazole induce apoptosis human primary cells lines. Notably, cause cell oxidative damage whereas metronidazole has no effect reactive...
A high premium has been put on researching the effects of cold spells because their adverse influence people's daily lives and health. The study aimed to find most appropriate definition spell in Shenzhen quantify impact mortality. Based mortality data from 2013 2017 meteorological pollutant same period, we quantified effect using eight different definitions framework a distributed lag non-linear model with quasi-Poisson distribution. In Shenzhen, low temperatures increase risk death more...
Temperature change is an important meteorological indicator reflecting weather stability. This study aimed to examine the effects of ambient temperature on non-accidental mortality using diurnal (DTR) and between neighboring days (TCN) from two perspectives, intra-day inter-day change, further, explore seasonal variations mortality, identify susceptible population investigate interaction apparent (AT). We collected daily data cause-specific air pollutants indicators in Shenzhen, China, 1...
Alzheimer’s disease (AD) is a chronic progressive neurodegenerative disorder that associated with learning, memory, and cognitive deficits. Neuroinflammation synapse loss are involved in the pathology of AD. Diverse measures have been applied to treat AD, but currently, there no effective treatment. Celastrol (CEL) pentacyclic triterpene isolated from Tripterygium wilfordii Hook F has shown enhance cell viability inhibit amyloid‐ β production induced by lipopolysaccharides vitro . In present...
Pulmonary bullae is a common complication of chronic obstructive pulmonary disease(COPD), causing the deterioration in lung function, leading to aggravated dyspnea and poor quality life for patients. The traditional therapeutic approach bullectomy using surgical thoracoscopy. disadvantage this postoperative complications high risk recurrence many In addition, some patients, due patient's physical conditions, such as function other diseases, could not be used. Therefore, new alternative...
The risk of fall seriously affects the health and quality life middle-aged elderly people, especially injury disability caused by which imposes a huge burden on family social medical care. Baduanjin exercise may be an effective intervention to enhance muscle strength stability lower limbs, improve balance ability gait reduce incidence falls, life, promote people. aim this study is summarize evidence systematically review efficacy safety function in people.We conducted systematic search...
Acute ischemic stroke (AIS) is the second leading cause of death worldwide. This study aims at assessing platelet morphology, ultrastructure and function changes platelets in acute patients by technique Structured Illumination Microscopy (SIM). assay collected platelet-rich plasma (PRP) from 11 AIS 12 healthy controls. Each PRP sample was divided into 7 groups:1) rest group; 2) Thrombin-treated 5 min 3) Thrombin plus 2MeSAMP-treated 4) Aspirin-treated 5) 1 h 6) 7) group. SIM applied to...
Objective To study whether BED-capture enzyme immunoassay (CEIA) is feasible to be used in wide-ranging population, we collect papers and conference abstracts related BED-CEIA HIV-1 incidence. Methods 10 are included for the discussion, regarding concordance between estimated incidence from results a cohort studies; 11 selected discuss misclassification on estimation of HIV-1incidence. Results Concordance two sets districts design research. Africa not so satisfactory, but researches, those...
This study explored the association between long-term consumption of genetically modified foods (GM foods) and risk chronic disease onset. The reviews development history GM their position in global food supply, introducing different types common gene editing techniques, as well assessments about safety. Based on a systematic analysis existing research, we relationship diseases. Furthermore, this discusses multiple factors uncertainties risk, including genetic environmental factors. Finally,...
Scientific and quantitative evaluation of the efficiency public medical health expenditure can help improve service capabilities. Based on data envelopment method, empirical analysis is carried out with original figures in 21 cities prefectures Sichuan Province from 2014 to 2018. There are obvious differences overall pure technical expenditures various Province. Except for five Chengdu, Aba Tibetan Qiang Autonomous Prefecture, Zigong, Ganzi Prefecture Ya'an, difference scale not very...
Abstract Platelets are important in acute ischemic stroke (AIS) thrombosis. The observation and evaluation of platelet ultrastructure efficacy antiplatelet drug AIS patients is difficult due to microscopic limitations sensitivity platelet. new super-resolution microscope (SIM) can accurately, quickly analyze the patients. We applied SIM observe morphology platelets with different state. images were analyzed specify dense granules α change Testing factor 4 (PF4) reflect releasing function....