A5104534743- Cancer-related molecular mechanisms research
- Cancer Mechanisms and Therapy
- Gut microbiota and health
- RNA modifications and cancer
- Barrier Structure and Function Studies
- Wnt/β-catenin signaling in development and cancer
- Lung Cancer Treatments and Mutations
- Inflammatory Bowel Disease
- Cancer-related gene regulation
- Microtubule and mitosis dynamics
- Pressure Ulcer Prevention and Management
- Vitamin D Research Studies
- Ubiquitin and proteasome pathways
- Lipid metabolism and biosynthesis
- Global Educational Reforms and Inequalities
- RNA Research and Splicing
- Cancer-related Molecular Pathways
- Sleep and related disorders
- Gout, Hyperuricemia, Uric Acid
- Circular RNAs in diseases
- Health Promotion and Cardiovascular Prevention
- Sleep and Work-Related Fatigue
- Renal cell carcinoma treatment
- Cardiovascular Health and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
People's Hospital of Cangzhou
2024
Kunming Children's Hospital
2024
Yan'an University
2023-2024
Second Affiliated Hospital of Xi'an Jiaotong University
2014-2021
Tianjin Medical University
2021
Nanjing Medical University
2016
Xi'an Jiaotong University
2014
The specific pathogenesis of UC is still unclear, but it has been clear that defects in intestinal barrier function play an important role it. There a temporary lack drugs for clinical treatment. Astragaloside IV (AS-IV) one the main active ingredients extracted from Astragalus root and common Chinese herbal medicine treatment gastrointestinal diseases. This study aimed to determine whether AS-IV therapeutic value DSS or LPS-induced epithelial dysfunction vivo vitro its potential molecular...
// Niu Zequn 1 , Zhang Xuemei 2 Li Wei Ming Zongjuan Zhong Yujie Hou Yanli Yuping Meng Xia Wang Deng Wenjing Fan Na Yang Shuanying Institute of Respiratory Medicine, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China Pediatric Hematology and Oncology Shanghai Oriental Shanghai, Correspondence to: Shuanying, e-mail: yangshuanying66@163.com Keywords: non-small cell lung cancer, LncRNA, TATDN1, invasion, metastasis Received: August 16, 2015 Accepted: January 21, 2016...
This study aims to explore the interplay between body mass index (BMI), neutrophils, triglyceride levels, and uric acid (UA). Understanding causal correlation UA health indicators, specifically its association with body's inflammatory conditions, is crucial for preventing managing various diseases. A retrospective analysis was conducted on 4,286 cases utilizing Spearman method. BMI, neutrophil count, levels were determined as key exposure factors. To further investigate correlation, a...
Cardiovascular disease (CVD) is now the most prevalent and debilitating affecting Chinese population, we aim to provide latest nationwide estimates on prevalence of main CVD risk factors. Using a complex, multistage, probability sampling design, cross-sectional study was performed in nationally representative sample 17,708 adults aged 45 years older from 28 provinces 2011–2012. Overall, age-standardized subjects having 1, 2, 3, or ≥ 4 5 factors 30.5%, 29.8%, 19.7%, 7.4%, respectively. The...
Lung cancer has been considered as one of the most important causes cancer-related mortality worldwide. To predict lung cancer, researchers identified several molecular markers. However, many underlying markers remain unclear. One these is Rab GDP dissociation inhibitor beta (GDIβ), which related to tumorigenicity, development and invasion. This study was designed analyze biological characteristics GDIβ detect mRNA protein expressions in cells; this also aimed investigate functions...
Angiomotin-like 2 (AMOTL2) is a key modulator of signaling transduction and participates in the regulation various cellular progresses under diverse physiological pathological conditions. However, whether AMOTL2 asthma pathogenesis has not been fully studied. In present work, we studied possible role mechanism regulating transforming growth factor-β1 (TGF-β1)-induced proliferation extracellular matrix (ECM) deposition airway smooth muscle (ASM) cells. Our results showed marked reductions...
As its etiology and pathogenesis is obscure, illustrating the molecular mechanism of lung cancer has become a serious urgent task. Studies have shown that fumarate hydratase (FH) tumor suppressor related to tumorigenesis, development, invasion. Our aim was analyze biological information FH, detect messenger ribonucleic acid (mRNA) protein expression FH in cells explore role tumorigenesis development cancer.We analyzed characteristics then utilized reverse transcription-polymerase chain...
Recurrent respiratory tract infections (RRTIs) have a complex pathogenic mechanism. There may be correlations between expression levels of serum 25-hydroxy-vitamin D (25-OH-D), regulatory T cells (Tregs), total immu-noglobulin E (IgE) and RRTIs. We aimed to explore the 25-OH-D, cluster differentiation 4 (CD4)+CD25+CD127- Tregs IgE in children with A 150 pneumonia were enrolled as subjects randomly assigned into control group (97 non-RRTIs) an observation (53 RRTIs). The CD4+CD25+CD127-...
<title>Abstract</title> <bold>Background</bold> As a chronic inflammatory disease with recurrent symptoms, ulcerative colitis (UC) is severely threatening human health worldwide high prevalence. Intestinal mucosal barriers stand the first line to maintain balance between food metabolism, nutrient absorption, and pathogen attacks. Although various signaling pathways have been found be associated intestinal barrier regulation, whether how PI3K/AKT pathway involved in gut function modulation...