A5091207072- Neural dynamics and brain function
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroscience and Music Perception
- Electrocatalysts for Energy Conversion
- Hearing Loss and Rehabilitation
- Advanced Photocatalysis Techniques
- Spatial Cognition and Navigation
- EEG and Brain-Computer Interfaces
- Genetic Associations and Epidemiology
- Technology and Human Factors in Education and Health
- MXene and MAX Phase Materials
- Retinal Diseases and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Catalytic Processes in Materials Science
- CO2 Reduction Techniques and Catalysts
- Sperm and Testicular Function
- Retinal Imaging and Analysis
- Reproductive Biology and Fertility
- RNA Interference and Gene Delivery
- Blind Source Separation Techniques
- Retinal and Optic Conditions
- Liver Disease Diagnosis and Treatment
- Categorization, perception, and language
South China University of Technology
2024-2025
Guangdong Academy of Medical Sciences
2024-2025
Southern Medical University
2024-2025
Guangdong Provincial People's Hospital
2024-2025
Tsinghua University
2017-2024
Massachusetts Eye and Ear Infirmary
2022
Harvard University
2022
Taizhou University
2022
Chinese Institute for Brain Research
2017-2018
Jinan University
2016
Background: The asymptomatic onset and extremely high mortality rate of aortic aneurysm (AA) highlight the urgency early detection timely intervention. alteration retinal vascular features (RVFs) can reflect systemic properties, be widely used as biomarker for cardiovascular disease risk prediction. Therefore, we aimed to investigate associations RVFs with AA its progression. Methods: In this prospective population-based cohort study, participants eligible fundus images without a history at...
Improving the electrocatalytic properties by regulating surface electronic structure of supported metals has always been a hot issue in electrocatalysis. Herein, two novel catalysts Pd/B-N-Ti3C2 and Pd/N-B-Ti3C2 are used as models to explore effect B N co-doping sequence on metals, together with ethanol oxidation reaction. The exhibit obviously stratified morphology, Pd nanoparticles having same amount both uniformly distributed surface. However, electron binding energy Ti elements is...
Neurons in sensory cortex exhibit a remarkable capacity to maintain stable firing rates despite large fluctuations afferent activity levels. However, sudden peripheral deafferentation adulthood can trigger an excessive, non-homeostatic cortical compensatory response that may underlie perceptual disorders including hypersensitivity, phantom limb pain, and tinnitus. Here, we show mice with noise-induced damage of the high-frequency cochlear base were behaviorally hypersensitive spared...
Systematic examination of the inputs and outputs nonlemniscal auditory thalamus will facilitate functional elucidation this complex structure in central system. In mice, comprehensive tracing studies that reveal long-range connectivity are lacking. To end, we used Cre-inducible anterograde monosynaptic retrograde viruses Calbindin-2A-dgCre-D Calretinin-IRES-Cre focusing on differences across subdivisions thalamus. We found that, 1) dorsal medial parts were predominantly connected to sensory...
Abstract Faithful representation of sound envelopes in primary auditory cortex (A1) is vital for temporal processing and perception natural sounds. However, the emergence cortical mechanisms during development remains poorly understood. Although inhibition has been proposed to play an important role this process, direct in-vivo evidence lacking. Using loose-patch recordings rat A1 immediately after hearing onset, we found that stimulus-following ability fast-spiking neurons was significantly...
ABSTRACT To comprehend the complex world around us, our brains are tasked with remarkable job of integrating multiple features into a cohesive whole. While previous studies have primarily focused on processing and integration independent features, here we investigated simultaneous encoding interdependent specifically head direction (HD) its temporal derivative, angular velocity (AHV), by first employing computational modeling HD systems to explore emergent algorithms then validated...
The protracted maturational process of temporal processing in layer 4 (L4) primary auditory cortex (A1) has been extensively studied. Accumulating evidences show that 5 (L5) receives direct thalamic inputs as well. How the responses L5 may developmentally emerge remains unclear. Using vivo loose-patch recordings rat A1, we found putative pyramidal (Pyr) neurons developing exhibited adult-like stimulus-following ability but less bursting shortly after hearing onset. Pyr adult A1 phase-locking...
ABSTRACT Throughout the brain, neurons exhibit a remarkable capacity to maintain stable firing rates despite large perturbations in afferent activity levels. As an exception, homeostatic regulation of neural often fails adult auditory system after hearing loss. Cochlear deafferentation caused by aging or noise exposure triggers widespread hyperactivity, particularly cortex (ACtx), which underlies perceptual disorders including tinnitus and hyperacusis. Here, we show that mice with...
Epilepsy is a neurological disorder characterized by the sudden abnormal discharging of brain neurons that can lead to encephalographic (EEG) abnormalities.In this study, data was obtained from epileptic patients with intracranial depth electrodes and analyzed using wavelet entropy algorithms in order locate foci.Significant increases signals were identified during multiple episodes clinical seizures.The results indicated algorithm capable identifying changes sources.Furthermore,...
In order to understand the role of protein zona pellucida 2 in fertilization, an antibody against a central segment peptide, 190-505 (Z2eH), was prepared. The influence on sperm-zona interaction tested using sperm-egg binding assay. effect fertility evaluated by passive immunization with anti-Z2eH antibody. Immunohistochemical assay showed that from rabbit reacted specifically natural mouse ovarian sections. Immunofluorescence bound zonae pellucidae ovulated oocytes and 2-cell embryos after...