- Spine and Intervertebral Disc Pathology
- Spinal Dysraphism and Malformations
- Spinal Fractures and Fixation Techniques
- Connective tissue disorders research
- Medical Imaging and Analysis
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Fetal and Pediatric Neurological Disorders
- Neonatal Health and Biochemistry
- Peripheral Nerve Disorders
- Apelin-related biomedical research
- Peroxisome Proliferator-Activated Receptors
- Autoimmune and Inflammatory Disorders
- Myofascial pain diagnosis and treatment
- Congenital gastrointestinal and neural anomalies
- Cardiovascular Disease and Adiposity
- Amino Acid Enzymes and Metabolism
- Inflammasome and immune disorders
- Ocular Diseases and Behçet’s Syndrome
- Neonatal Respiratory Health Research
- Cerebrospinal fluid and hydrocephalus
- interferon and immune responses
- Schizophrenia research and treatment
- Eicosanoids and Hypertension Pharmacology
- S100 Proteins and Annexins
Capital Medical University
2016-2025
Children's Hospital of Fudan University
2024
First Affiliated Hospital of Zhengzhou University
2023
Beijing Children’s Hospital
2021-2023
Baoding People's Hospital
2023
Xian Center for Disease Control and Prevention
2022
Beijing YouAn Hospital
2020-2022
Beijing Tongren Hospital
2016
Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and percutaneous pedicle (OLIF-PF) in treatment single-level or 2-level degenerative lumbar disease.Methods: Between January 2017 2021, 71 patients were treated OLIF. The demographic data, clinical outcomes, radiographic complications compared among 3 groups.Results: operative time intraoperative blood loss (p<0.05) OLIF-AF groups lower than OLIF-PF...
OBJECTIVE This study aimed to investigate the differences in clinical features, diagnostic examination, treatment, and pathological results between adult-onset pediatric-onset tethered cord syndrome (TCS). METHODS The authors searched PubMed, Embase, Cochrane Library databases through January 2023 for reports on TCS, extracting information imaging data, treatment modalities, prognosis, research results. A total of 6135 cases from 246 articles were included analysis. review was conducted...
Background: Apelin system plays a significant role in central blood pressure regulation, but its neural control of myocardial injury protection is poorly understood. Thus, this study was undertaken to evaluate the effects apelin-13 paraventricular nucleus (PVN) on infarction (MI) and ischemia/reperfusion (I/R). Methods: The cardiac functions were assessed after microinjecting or transferring gene into rat models with Results: In MI rats, we showed that expression decreased PVN, V1a receptor...
To investigate the genetic, clinical, and post-treatment characteristics of patients with glycogen storage disease type Ⅲ (GSD Ⅲ).
Objective: To compare the efficacy among stand-alone oblique lateral lumbar interbody fusion (OLIF-SA), OLIF combined with screw internal fixation (OLIF-AF) and posterior percutaneous pedicle (OLIF-PF) in treatment of degenerative diseases. Methods: The clinical data patients diseases who underwent OLIF-SA, OLIF-AF OLIF-PF Department Neurosurgery, Xuanwu Hospital, Capital Medical University from January 2017 to 2021 were retrospectively analyzed. Patients' visual analogue score (VAS)...
To summarize the clinical characteristics, diagnosis, and treatment of blepharokeratoconjunctivitis (BKC).Retrospective analysis. One hundred seventy-two patients were diagnosed as BKC between January 2012 December 2014 at Beijing Tongren Hospital. The degrees blepharitis BKC, therapeutic effect evaluated.The aged from 2 to 78 years (mean, 27±18 years). Forty-nine (28.5%) males, 123 (71.5%) females. five had photograph records lid margin, cornea, conjunctiva. was unilateral in 28 (26.7%)...
Objective: To investigate the mechanism of action peroxisome proliferator-activated receptor α (PPARα)-mediated CCAAT/enhancer binding protein homologous (CHOP) signaling molecule with response to inflammation in mice acute liver failure. Methods: C57BL/6 were used as research subjects, and D-galactose (D-GalN) combined lipopolysaccharide (LPS) was injected intraperitoneally establish a mouse model PPARα activated by Wy-14643. CHOP expression promoted plasmids. Liver pathological changes...
To explore the association between self-reported gingival bleeding and prevalent hypertension among adults in Zhejiang with a cross-sectional study.
Objective: To investigate the expression and role of asparte-specific cysteine protease (Caspase)-1, inflammasomes key molecule, in hepatitis B virus (HBV)-related diseases. Methods: HBV-related liver disease patients' serum (438 cases) tissue (82 samples were collected from Beijing You'an Hospital affiliated with Capital Medical University. The mRNA level caspase-1 was detected by real-time fluorescence quantitative PCR (qRT-PCR). protein Caspase-1 immunofluorescence method. activity using...
患儿 男,10月龄,因“点头拥抱样动作2个月”就诊。主要表现为智力及运动发育迟缓,婴儿痉挛症和小头畸形。全外显子基因测序提示PHGDH基因c.946-2A>G和c.766G>A,为复合杂合变异,诊断为磷酸甘油酸脱氢酶缺乏,该病临床症状缺乏特异性,按癫痫发作类型选择抗癫痫药物治疗可以部分有效控制发作。.
偏头痛是常见的原发性头痛,表现为反复发作的偏侧或双侧搏动性中到重度头痛,常伴有恶心或呕吐、畏光和畏声等症状。迄今为止,偏头痛的发病机制仍不明确,尚缺乏特异性的诊疗标记物。无创性神经影像学技术的发展,为探索偏头痛的病理机制提供了有效的技术手段。本文从磁共振成像(MRI)与正电子发射断层扫描成像(PET)的角度,对偏头痛的脑结构与脑功能影像学研究进行了综述,旨在为偏头痛的诊疗提供参考。.
患儿 男,10岁,以“确诊横纹肌肉瘤5年余,咳嗽13 d”于2021年7月入北京儿童医院呼吸二科,既往规律放疗、化疗。门诊查胸部CT发现左下肺野内团状高密度影,为明确诊断于虚拟支气管镜导航系统引导下,经支气管镜行肺外周病变活检术留取样本,病理诊断横纹肌肉瘤(左下)肺转移,术中术后无并发症发生,确诊后转儿童肿瘤内科调整化疗方案继续治疗。.
Objective: To investigate the clinical characteristics, treatment and prognosis of congenital pulmonary airway malformation (CPAM) complicated with chronic aspergillosis (CPA) in children. Methods: The manifestation, laboratory test, radiological feature, 4 pediatric patients diagnosis CPAM CPA ascertained between March 2016 April 2020 at Department No.2 Respiratory Medicine Thoracic Surgery Beijing Children's Hospital were retrospectively analyzed. Results: children included 2 males...