X Y Zhang

ORCID: 0009-0001-0768-8034
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About
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Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Dysraphism and Malformations
  • Spinal Fractures and Fixation Techniques
  • Connective tissue disorders research
  • Medical Imaging and Analysis
  • Tracheal and airway disorders
  • Congenital Diaphragmatic Hernia Studies
  • Fetal and Pediatric Neurological Disorders
  • Neonatal Health and Biochemistry
  • Peripheral Nerve Disorders
  • Apelin-related biomedical research
  • Peroxisome Proliferator-Activated Receptors
  • Autoimmune and Inflammatory Disorders
  • Myofascial pain diagnosis and treatment
  • Congenital gastrointestinal and neural anomalies
  • Cardiovascular Disease and Adiposity
  • Amino Acid Enzymes and Metabolism
  • Inflammasome and immune disorders
  • Ocular Diseases and Behçet’s Syndrome
  • Neonatal Respiratory Health Research
  • Cerebrospinal fluid and hydrocephalus
  • interferon and immune responses
  • Schizophrenia research and treatment
  • Eicosanoids and Hypertension Pharmacology
  • S100 Proteins and Annexins

Capital Medical University
2016-2025

Children's Hospital of Fudan University
2024

First Affiliated Hospital of Zhengzhou University
2023

Beijing Children’s Hospital
2021-2023

Baoding People's Hospital
2023

Xian Center for Disease Control and Prevention
2022

Beijing YouAn Hospital
2020-2022

Beijing Tongren Hospital
2016

Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF combined with anterolateral screw fixation (OLIF-AF), and percutaneous pedicle (OLIF-PF) in treatment single-level or 2-level degenerative lumbar disease.Methods: Between January 2017 2021, 71 patients were treated OLIF. The demographic data, clinical outcomes, radiographic complications compared among 3 groups.Results: operative time intraoperative blood loss (p<0.05) OLIF-AF groups lower than OLIF-PF...

10.14245/ns.2244954.477 article EN cc-by-nc Neurospine 2023-06-30

OBJECTIVE This study aimed to investigate the differences in clinical features, diagnostic examination, treatment, and pathological results between adult-onset pediatric-onset tethered cord syndrome (TCS). METHODS The authors searched PubMed, Embase, Cochrane Library databases through January 2023 for reports on TCS, extracting information imaging data, treatment modalities, prognosis, research results. A total of 6135 cases from 246 articles were included analysis. review was conducted...

10.3171/2024.3.focus23899 article EN Neurosurgical FOCUS 2024-06-01

Background: Apelin system plays a significant role in central blood pressure regulation, but its neural control of myocardial injury protection is poorly understood. Thus, this study was undertaken to evaluate the effects apelin-13 paraventricular nucleus (PVN) on infarction (MI) and ischemia/reperfusion (I/R). Methods: The cardiac functions were assessed after microinjecting or transferring gene into rat models with Results: In MI rats, we showed that expression decreased PVN, V1a receptor...

10.1101/2024.10.23.619957 preprint EN cc-by-nd 2024-10-27

To investigate the genetic, clinical, and post-treatment characteristics of patients with glycogen storage disease type Ⅲ (GSD Ⅲ).

10.3760/cma.j.cn501113-20240719-00336 article EN PubMed 2024-11-20

Objective: To compare the efficacy among stand-alone oblique lateral lumbar interbody fusion (OLIF-SA), OLIF combined with screw internal fixation (OLIF-AF) and posterior percutaneous pedicle (OLIF-PF) in treatment of degenerative diseases. Methods: The clinical data patients diseases who underwent OLIF-SA, OLIF-AF OLIF-PF Department Neurosurgery, Xuanwu Hospital, Capital Medical University from January 2017 to 2021 were retrospectively analyzed. Patients' visual analogue score (VAS)...

10.3760/cma.j.cn112137-20221123-02478 article EN PubMed 2023-02-21

To summarize the clinical characteristics, diagnosis, and treatment of blepharokeratoconjunctivitis (BKC).Retrospective analysis. One hundred seventy-two patients were diagnosed as BKC between January 2012 December 2014 at Beijing Tongren Hospital. The degrees blepharitis BKC, therapeutic effect evaluated.The aged from 2 to 78 years (mean, 27±18 years). Forty-nine (28.5%) males, 123 (71.5%) females. five had photograph records lid margin, cornea, conjunctiva. was unilateral in 28 (26.7%)...

10.3760/cma.j.issn.0412-4081.2016.03.006 article EN PubMed 2016-03-01

Objective: To investigate the mechanism of action peroxisome proliferator-activated receptor α (PPARα)-mediated CCAAT/enhancer binding protein homologous (CHOP) signaling molecule with response to inflammation in mice acute liver failure. Methods: C57BL/6 were used as research subjects, and D-galactose (D-GalN) combined lipopolysaccharide (LPS) was injected intraperitoneally establish a mouse model PPARα activated by Wy-14643. CHOP expression promoted plasmids. Liver pathological changes...

10.3760/cma.j.cn501113-20200608-00298 article EN PubMed 2020-07-20

To explore the association between self-reported gingival bleeding and prevalent hypertension among adults in Zhejiang with a cross-sectional study.

10.3760/cma.j.cn112338-20210922-00744 article EN PubMed 2022-08-10

Objective: To investigate the expression and role of asparte-specific cysteine protease (Caspase)-1, inflammasomes key molecule, in hepatitis B virus (HBV)-related diseases. Methods: HBV-related liver disease patients' serum (438 cases) tissue (82 samples were collected from Beijing You'an Hospital affiliated with Capital Medical University. The mRNA level caspase-1 was detected by real-time fluorescence quantitative PCR (qRT-PCR). protein Caspase-1 immunofluorescence method. activity using...

10.3760/cma.j.cn501113-20210512-00231 article EN PubMed 2022-11-20

患儿 男,10月龄,因“点头拥抱样动作2个月”就诊。主要表现为智力及运动发育迟缓,婴儿痉挛症和小头畸形。全外显子基因测序提示PHGDH基因c.946-2A>G和c.766G>A,为复合杂合变异,诊断为磷酸甘油酸脱氢酶缺乏,该病临床症状缺乏特异性,按癫痫发作类型选择抗癫痫药物治疗可以部分有效控制发作。.

10.3760/cma.j.cn112140-20230219-00113 article EN PubMed 2023-07-02

偏头痛是常见的原发性头痛,表现为反复发作的偏侧或双侧搏动性中到重度头痛,常伴有恶心或呕吐、畏光和畏声等症状。迄今为止,偏头痛的发病机制仍不明确,尚缺乏特异性的诊疗标记物。无创性神经影像学技术的发展,为探索偏头痛的病理机制提供了有效的技术手段。本文从磁共振成像(MRI)与正电子发射断层扫描成像(PET)的角度,对偏头痛的脑结构与脑功能影像学研究进行了综述,旨在为偏头痛的诊疗提供参考。.

10.3760/cma.j.cn112138-20220922-00706 article EN PubMed 2023-10-01

患儿 男,10岁,以“确诊横纹肌肉瘤5年余,咳嗽13 d”于2021年7月入北京儿童医院呼吸二科,既往规律放疗、化疗。门诊查胸部CT发现左下肺野内团状高密度影,为明确诊断于虚拟支气管镜导航系统引导下,经支气管镜行肺外周病变活检术留取样本,病理诊断横纹肌肉瘤(左下)肺转移,术中术后无并发症发生,确诊后转儿童肿瘤内科调整化疗方案继续治疗。.

10.3760/cma.j.cn112140-20220826-00754 article ZH-CN PubMed 2023-02-02

Objective: To investigate the clinical characteristics, treatment and prognosis of congenital pulmonary airway malformation (CPAM) complicated with chronic aspergillosis (CPA) in children. Methods: The manifestation, laboratory test, radiological feature, 4 pediatric patients diagnosis CPAM CPA ascertained between March 2016 April 2020 at Department No.2 Respiratory Medicine Thoracic Surgery Beijing Children's Hospital were retrospectively analyzed. Results: children included 2 males...

10.3760/cma.j.cn112140-20210421-00334 article EN Zhonghua erke zazhi 2021-10-02
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