A5076356156- Water Treatment and Disinfection
- Chemical Analysis and Environmental Impact
- RNA modifications and cancer
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Per- and polyfluoroalkyl substances research
- Metabolism, Diabetes, and Cancer
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial biofilms and quorum sensing
- Pancreatic function and diabetes
- Genetics and Neurodevelopmental Disorders
- Microbial Fuel Cells and Bioremediation
- Wastewater Treatment and Nitrogen Removal
- Fluoride Effects and Removal
- Mine drainage and remediation techniques
- Environmental remediation with nanomaterials
- Diabetes and associated disorders
- PI3K/AKT/mTOR signaling in cancer
- Algal biology and biofuel production
- Urban and Freight Transport Logistics
- Advanced Nanomaterials in Catalysis
- Hemostasis and retained surgical items
- Neurological disorders and treatments
- Fungal and yeast genetics research
- Digestive system and related health
- Blood disorders and treatments
Tsinghua University
2024
State Key Joint Laboratory of Environment Simulation and Pollution Control
2024
Northeast Normal University
2018-2024
Beijing Children’s Hospital
2022-2024
Capital Medical University
2022-2024
Hengyang Normal University
2024
Center for Children
2023
Sichuan University
2023
West China Second University Hospital of Sichuan University
2023
Weatherford College
2022
As an important therapeutic target, carbonic anhydrase IX (CAIX) is crucial in pH regulation of hypoxic solid tumors, thus keeping the survival them acidic microenvironment, and promoting their proliferation, invasion metastasis. To degrade endogenous CAIX, three bifunctional compounds were designed according to integrin-facilitated lysosomal degradation (IFLD) strategy. These are composed a CAIX binding ligand, integrin-recognizing connected via linker, which could induce integrin-...
Globally, cyanobacterial blooms have become serious problems in eutrophic water. Most previous studies focused on environmental factors but neglected the role of quorum sensing (QS) bloom development and control. This study explored a key molecule (QSM) that promotes cell growth then proposed targeted quencher to control blooms. A new QSM 3-OH-C4-HSL was identified with high-resolution mass spectrometry. It found regulate cellular carbon metabolism energy as means promote Microcystis...
Variants in membrane-bound transcription factor peptidase, site 1 (MBTPS1) gene, can result clinically rare spondyloepiphyseal dysplasia of Kondo-fu type (OMIM #618392, SEDKF), Silver-Russell syndrome, and CAOP (cataract, alopecia, oral mucosal disorder, psoriasis-like) syndrome.A 6-year-old Chinese male child diagnosed with SEDKF underwent 3 years growth hormone therapy. A genetic examination revealed two new nonsense variants the MBTPS1 gene on chromosome 16q23-q24 compound heterozygotes...
and D)gest)ve D)seases Bao D
To investigate the characteristics of 4 Chinese patients with Bartter syndrome type 3 (BS Type 3).
Maturity-onset diabetes of the young, type 13 (MODY13) is a specific subclass monogenic mellitus that does not exhibit typical clinical manifestations diabetes, necessitating use genetic testing for accurate diagnosis. With progression and MODY, number reported MODY13 cases has reached minimum 22. Nevertheless, there remains dearth information regarding patients diagnosed with presenting synonymous variants. This study presents description features 9-year-old male patient MODY13. A...