- Experimental Behavioral Economics Studies
- Decision-Making and Behavioral Economics
- Game Theory and Applications
- Analog and Mixed-Signal Circuit Design
- Consumer Market Behavior and Pricing
- Economic theories and models
- Evolutionary Game Theory and Cooperation
- CCD and CMOS Imaging Sensors
- Protein Degradation and Inhibitors
- Sustainable Development and Environmental Policy
- Complex Systems and Time Series Analysis
- Advancements in Semiconductor Devices and Circuit Design
- Behavioral Health and Interventions
- Economic and Environmental Valuation
- Law, Economics, and Judicial Systems
- Psychology of Social Influence
- Game Theory and Voting Systems
- Radio Frequency Integrated Circuit Design
- Service-Oriented Architecture and Web Services
- Social and Intergroup Psychology
- MRI in cancer diagnosis
- Mental Health Research Topics
- Immune cells in cancer
- Autophagy in Disease and Therapy
- Angiogenesis and VEGF in Cancer
Shenzhen Institutes of Advanced Technology
2022-2025
Chinese Academy of Sciences
2022-2025
Guangdong University of Technology
2023-2024
Lancaster University
2022-2024
Fuzhou Maternity and Child Health Care Hospital
2023
Xintai People's Hospital
2022
Lancaster University Ghana
2021
University of East Anglia
2012-2020
Jiangsu Provincial Academy of Forestry Science and Management
2019
University of Warwick
2014
As effective ways to regulate protein levels, targeted degradation technologies have attracted great attention in recent years. Here, we established a novel integrin-facilitated lysosomal (IFLD) strategy degrade extracellular and cell membrane proteins using bifunctional compounds as molecular degraders. By conjugation of target protein-binding ligand with an integrin-recognition ligand, the resulting degrader proved be highly efficient induce internalization subsequent or integrin-...
We investigate the effects of a range different types anchor on WTP and WTA valuations familiar consumer products, elicited through individuals' buying or selling decisions at given prices. find anchoring only when value is framed as plausible price for good which individual potential buyer seller. Anchoring are stronger than WTP. conclude that can affect market behaviour, but not all anchors effective.
As an important therapeutic target, carbonic anhydrase IX (CAIX) is crucial in pH regulation of hypoxic solid tumors, thus keeping the survival them acidic microenvironment, and promoting their proliferation, invasion metastasis. To degrade endogenous CAIX, three bifunctional compounds were designed according to integrin-facilitated lysosomal degradation (IFLD) strategy. These are composed a CAIX binding ligand, integrin-recognizing connected via linker, which could induce integrin-...
In an experiment on markets for services, we find that consumers are likely to stick default tariffs and achieve suboptimal outcomes. We inattention the task of choosing a better tariff is be substantial problem in addition any complexity effect. The institutional setup which primarily model our UK electricity gas markets, conclusion new measures by regulator Ofgem improve consumer outcomes limited impact.
This paper reports an experimental investigation of Schelling's theory focal points that compares group and individual behaviour. We find that, when players' interests are perfectly aligned, groups more often choose the salient option achieve higher coordination success than individuals. However, in games with conflicts interest, do not always perform better individuals, especially degree conflict is substantial. also outperform individuals identifying solution to problem requires some level...
In an experiment on markets for services, we find that consumers are likely to stick defaults and achieve suboptimal outcomes. We unpack two key psychological reasons why they do this - complexity (in terms of non-linearity, number bundling tariffs) consumer inattention. The induced by product bundling, non-linearity tariffs has important role, but is overstated if the explanatory power inattention neglected. show a ‘smart nudge’ policy automatically switching default can be used exploit...
We report the results of a new tacit bargaining experiment that provides two key insights about effects payoff inequality on coordination and cooperation towards efficient outcomes. The features novel Pizza Night game, which can disentangle conflict interest. When relies focal points based labelling properties, does not interfere with successful use those properties. there are efficiency cues assist coordination, is an obstacle to maximisation efficiency. Conflict interest main barrier coordination.
Abstract Background Transient ischemic attack (TIA) is a major risk factor for the occurrence of cerebral infarction (CI). This study aimed to evaluate predictive value synthetic role miR‐200b‐3p, ABCD 2 score, and carotid ultrasound CI onset in patients with TIA. Methods Expression miR‐200b‐3p was detected by reverse transcription quantitative PCR stenosis degree evaluated using examination. Association scores assessed t ‐test chi‐square test. Logistic regression analysis used judge ability...
Most social preference theories are based on observations of nonvoluntary interactions. Nonselfish behavior may take fundamentally different forms in voluntary interactions, such as market transactions. We investigate the "Principle Mutual Benefit"—an injunctive norm requiring individuals who enter interactions voluntarily to conform common expectations about within them. This induces patterns inconsistent with existing and allows extrinsic incentives crowd trustworthiness. embed this a...
A low-power low-jitter phase-locked loop (PLL) with phase noise improvement for radio frequency transceivers is presented in this paper. The in-band and out-of-band are both reduced due to the time-amplifying technique class-C voltage-controlled oscillator (VCO), respectively. In addition, a low current mismatch charge pump (CP) used here guarantee reference spur. proposed PLL fabricated 65-nm CMOS mixed-signal process an area of 0.220 mm2, clock 150 MHz. measurement results show that...
We experimentally test whether increasing the salience of payoff-irrelevant focal points (Schelling, 1960) can counteract negative impact conflicts interest on coordination. The intuition is that, in presence conflict, solution to coordination dilemma offered by point loses importance. Increasing its increases relevance and, therefore, success. When we vary label between subjects, find support for this conjecture games with a constant degree similar battle sexes games, but not that feature...
The Dll4-Notch signaling pathway plays a crucial role in the regulation of angiogenesis and is promising therapeutic target for diseases associated with abnormal angiogenesis, such as cancer ophthalmic diseases. Here, we find that polyethylenimine (PEI), cationic polymer widely used nucleic acid transfection reagents, can Notch ligand Dll4. By immunostaining immunoblotting, demonstrate PEI significantly induces clearance cell-surface Dll4 facilitates its degradation through lysosomal...
Understanding the best ways to incentivise recycling and improve efficiency of waste practices is a key environmental, social, economic management problem that needs addressing.We search for solutions this issue by testing effectiveness two incentive mechanisms (a piece-rate lottery-based systems). We run similar field experiment in three different locations, namely student, residential workplace environment, verify robustness our findings thus increase confidence external validity...
Gaudeul and Sugden [Gaudeul A, R (2012) Spurious complexity common standards in markets for consumer goods. Economica 79(314):209–225] have hypothesized that when some but not all competing products are priced a standard, consumers who liable to make errors cross-standard price comparisons use decision rules discriminate favor of common-standard offers. Such behavior incentivizes sellers standards. We report an experimental test this hypothesis, using choice tasks similar those represented...
Abstract Self-control failure occurs when an individual experiences a conflict between immediate desires and longer-term goals, recognises psychological forces that hinder goal-directed action, tries to resist them but fails in the attempt. Behavioural economists often invoke assumptions about self-control justify proposals for policy interventions. These arguments require workable methods eliciting individuals’ goals verifying occurrences of failure, developing such confronts two problems....