A5103058491- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Metal-Organic Frameworks: Synthesis and Applications
- MicroRNA in disease regulation
- Plant Gene Expression Analysis
- Pharmacological Effects and Toxicity Studies
- Cancer-related cognitive impairment studies
- Plant biochemistry and biosynthesis
- Atrial Fibrillation Management and Outcomes
- Epilepsy research and treatment
- Semantic Web and Ontologies
- Phytochemistry and Biological Activities
- Diabetic Foot Ulcer Assessment and Management
- Pancreatic and Hepatic Oncology Research
- Gas Sensing Nanomaterials and Sensors
- Phytochemicals and Antioxidant Activities
- Ferroptosis and cancer prognosis
- Biomedical Text Mining and Ontologies
- Cancer Risks and Factors
- Crystal structures of chemical compounds
- Environmental Impact and Sustainability
- Autophagy in Disease and Therapy
- Decision-Making and Behavioral Economics
- Analytical Chemistry and Sensors
- Mycobacterium research and diagnosis
Lite-On Technology Corporation (China)
2025
Huazhong University of Science and Technology
2015-2025
Central Hospital of Wuhan
2025
State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering
2025
Tsinghua University
2025
Zhejiang Cancer Hospital
2024
Chinese Academy of Sciences
2019-2024
Hebei University of Technology
2024
Shijiazhuang University
2024
Changzhou No.2 People's Hospital
2018-2024
Purpose: To investigate the potential association between serum concentrations of high mobility group protein B1 (HMGB1) and receptor for advanced glycation end-products (RAGE) in relation to occurrence restenosis following interventional therapy lower extremity vascular disease patients diagnosed with type 2 diabetes mellitus (T2DM). Patients Methods: From March 2023 January 2024, 96 T2DM who underwent 6-month follow-up our hospital were studied. divided into in-stent (ISR) (n=38)...
A novel MOF shows distinct solvent-dependent fluorescence and multi-responsive sensing behavior for some NACs, especially 4-NA 2-M-4-NA.
Abstract Emerging evidence suggests that long noncoding RNA (lncRNA) plays pivotal roles in regulating various biological process human cancers. Titin-antisense RNA1 (TTN-AS1) has been regarded as a tumor promoting lncRNA numerous However, the clinical significance and function of TTN-AS1 lung adenocarcinoma (LUAD) remain unclear. In present study, we revealed expression was upregulated LUAD tissues cell lines. High associated with TNM stage lymph node metastasis patients. addition, high...
Diagnosis of benign and malignant small nodules the lung remains an unmet clinical problem which is leading to serious false positive diagnosis overtreatment. Here, we developed a serum protein fishing-based spectral library (ProteoFish) for data independent acquisition analysis machine learning-boosted panel early Non-Small Cell Lung Cancer (NSCLC) classification nodules. We established extensive NSCLC bank consisting 297 subjects. After testing 5 feature extraction algorithms six learning...
Detection of serum protein biomarkers is extremely challenging owing to the superior complexity serum. Here, we report a method proteome fishing from It uses magnetic nanoparticle-protein corona and multiplexed aptamer panel, which incubated with for biomarker recognition. To transfer detection detection, established CRISPR/Cas12a-based orthogonal multiplex sensing (COMPASS) platform by profiling aptamers clinical nonsmall cell lung cancer (NSCLC) samples. Furthermore, determined four out...
Abstract Objective Explore the feasibility of a mobile health(mHealth) and virtual reality (VR) based nutrition-exercise-psychology integrated rehabilitation model in Chinese cancer patients. Methods We recruited patients Oncology department Affiliated Changzhou No. 2 People’s Hospital Nanjing Medical University from October 2022 to April 2023. The program was provided by team medical oncologists, dietitians, psychotherapists, oncology specialist nurses. Participants received standard...
The ozone micro-nano-bubble-enhanced oxidation (O3MNBEO) technology has shown great potential for organics-contaminated groundwater remediation in laboratory studies. However, few studies addressed its effectiveness engineering practices as well the impact on environment. In this study, a field demonstration was conducted to investigate efficiency of O3MNBEO remediating contaminated by various organic compounds. exhibited high removal efficiencies ranging from 85 100% benzene and...
Lung cancer is the most common cause of cancer-related mortality worldwide, and nonsmall cell lung (NSCLC) accounts for 80% all pulmonary carcinomas. Recently, long noncoding RNAs (lncRNAs) have been paid attention exploring treatment various diseases. Upregulation DiGeorge syndrome critical region gene 5 (DGCR5) predicts better squamous carcinoma prognosis; therefore, we explore role DGCR5 in our present study. Consecutive patients with LC were treated hospital between January 2015 2016....
Acute kidney injury (AKI) with maladaptive tubular repair leads to renal fibrosis and progresses chronic disease (CKD). At present, there is no curative drug interrupt AKI-to-CKD progression. The nuclear factor of the activated T cell (NFAT) family was initially identified as a transcription expressed in most immune cells involved cytokine genes other critical for response. NFAT2 also epithelial (RTECs) podocytes plays an important regulatory role kidney. In this study, we investigated...
MYB transcription factors of plants play important roles in flavonoid synthesis, aroma regulation, floral organ morphogenesis, and responses to biotic abiotic stresses. Cymbidium ensifolium is a perennial herbaceous plant belonging Orchidaceae, with special flower colors high ornamental value. In this study, total 136 CeMYB were identified from the genome C. ensifolium, including 27 1R-MYBs, 102 R2R3-MYBs, 2 3R-MYBs, 4R-MYBs, 3 atypical MYBs. Through phylogenetic analysis combination...
A single-stage TODGA column for the separation of Nd from geological materials isotope analysis as NdO<sup>+</sup> by TIMS.
While a large number of well-known knowledge bases (KBs) in life science have been published as Linked Open Data, there are few KBs Chinese. However, Chinese necessary when we want to automatically process and analyze electronic medical records (EMRs) Of all, the symptom KB is most seriously need, since symptoms starting point clinical diagnosis. We publish public Chinese, including symptoms, departments, diseases, medicines, examinations well relations between above related entities. To...
Baicalin is a flavonoid extracted from Scutellariae Radix and shows variety of biological activities as reducing lipids, diminishing inflammation, inhibiting bacterial infection. However, there no report baicalin against CVB3 In this study, we found that can reduce viral titer in dose-dependent manner vitro at dose with direct virucidal effect. Moreover, revealed also improve survival rate, heart weight/body weight ratio, prevent virus replication, relieve myocardial inflammation the acute...
Making time-limited offers is a common retail pricing strategy. Economic theory implies that such inhibit price search, making markets less competitive. We investigate experimentally whether this effect intensified by behavioural factors – specifically, feedback-conditional regret, reduced decision quality due to time constraints, and aversion small-scale risk. Participants choose from sequence of alternative offers, one which might be time-limited, under various conditions. These search...
While a large number of well-known knowledge bases (KBs) in life science have been published as Linked Open Data, there are few KBs Chinese. However, Chinese necessary when we want to automatically process and analyze electronic medical records (EMRs) Of all, the symptom KB is most seriously need, since symptoms starting point clinical diagnosis. Furthermore, expressions used describing practice diverse, which makes it hard collect such KB. In this paper, publish public The constructed by...
The basic helix-loop-helix (bHLH) transcription factors are widely distributed across eukaryotic kingdoms and participate in various physiological processes. To date, the bHLH family has been identified functionally analyzed many plants. However, systematic identification of yet to be reported orchids. Here, 94 were from Cymbidium ensifolium genome divided into 18 subfamilies. Most CebHLHs contain numerous cis-acting elements associated with abiotic stress responses phytohormone responses. A...
To investigate the prevalence of and risk factors for leukopenia in tuberculosis patients impact anti-tuberculosis regimens on occurrence newly treated patients.A total 1,904 were included study. A cross-sectional survey was initially conducted, then influencing identified using Logistic regression analysis. Non-treatment peripheral blood leukocyte counts analyzed univariate COX proportional hazards models. Covariate analysis used to assess independent effect different counts.Being female,...
Bridging integrator 1 (BIN1) has showed outstanding tumor-suppressive potential via inhibiting c-MYC-mediated tumorigenesis. However, a frequent phosphorylation of c-MYC at Ser-62 site could block the BIN1/c-MYC interaction and limits effect BIN1. Cyclin-dependent kinase 5 (CDK5), generally dysregulated protein in various carcinomas, can mediate site. whether existence CDK5 remains unclear.The expression BIN1 non-small cell lung cancer (NSCLC) lines were measured. was knocked down...