A5010629363- Hepatitis B Virus Studies
- Gut microbiota and health
- 3D Printing in Biomedical Research
- Hepatitis C virus research
- Liver physiology and pathology
- Long-Term Effects of COVID-19
- Helicobacter pylori-related gastroenterology studies
- Liver Disease Diagnosis and Treatment
- Pancreatic function and diabetes
- COVID-19 and healthcare impacts
- Caveolin-1 and cellular processes
- COVID-19 and Mental Health
- Ferroptosis and cancer prognosis
- Hepatitis Viruses Studies and Epidemiology
- Cancer-related molecular mechanisms research
Hangzhou First People's Hospital
2022-2025
Zhejiang University
2022-2025
Zhejiang Provincial People's Hospital
2025
Hangzhou Medical College
2025
Tongde Hospital of Zhejiang Province
2023
Westlake University
2022
Ischemia-reperfusion injury (IRI) is a major obstacle in liver transplantation, especially with steatotic donor livers. Dysbiosis of the gut microbiota has been implicated modulating IRI, and Lachnospiraceae plays pivotal role regulating host inflammatory immune responses, but its specific transplantation IRI remains unclear. This study explores whether can mitigate underlying mechanisms. We found Lachnospiraceae-bacterium (Lachn.) abundance was significantly reduced rats cirrhosis....
Abstract Hepatic steatosis significantly elevates the vulnerability of graft to ischemia-reperfusion (I/R) injury during liver transplantation (LT). We investigated protective role insulin-induced gene 2 (Insig2) in steatotic liver’s I/R and underlying mechanisms. Employing mouse model with Insig2 knock-out or hepatocyte-specific overexpression high-fat diets induce steatosis, we subjected these mice hepatic injury. The primary hepatocytes isolated from were used vitro hypoxia/reoxygenation...
<title>Abstract</title> Patients with end-stage liver disease often have intestinal flora dysbiosis. Exploring the causal relationship between abundance and cirrhosis or cancer is significant. In this study, we first demonstrated was detrimental to by two-sample Mendelian randomization (MR) analysis. Then, used bidirectional MR verify two-way gut (including 16 classes, 32 families, 119 genera, 20 orders, 9 phyla) diseases. Inverse variance weighted (IVW) primary method for examining...
Abstract To explore depression prevalence and related risk factors among elderly coronavirus disease 2019 (COVID‐19) survivors, while also evaluating research characteristics. We searched Web of Science, PubMed, Embase, Scopus, CNKI Wanfang Data for studies that reported COVID‐19 in older adults. ‘Bibliometrix’ facilitated bibliometric analysis information visualisation. Random‐effects models merged relevant risks. Publication bias its impact were examined using funnel plots, Begg's test,...