Zhengfei Qi

ORCID: 0009-0001-1797-9353
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Research Areas
  • Thermal Regulation in Medicine
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Arrest and Resuscitation
  • Electrospun Nanofibers in Biomedical Applications
  • Magnesium Oxide Properties and Applications
  • Biochemical effects in animals
  • Bone Tissue Engineering Materials
  • Neonatal and fetal brain pathology
  • Health, Environment, Cognitive Aging
  • Photoacoustic and Ultrasonic Imaging
  • Anesthesia and Neurotoxicity Research
  • Polymer composites and self-healing
  • Cardiovascular Health and Risk Factors
  • Nuclear Receptors and Signaling
  • Cardiac Ischemia and Reperfusion
  • Parkinson's Disease Mechanisms and Treatments
  • Ginkgo biloba and Cashew Applications
  • Magnesium Alloys: Properties and Applications
  • Hydrogen's biological and therapeutic effects
  • Ultrasound and Hyperthermia Applications

Anhui Medical University
2025

Chinese Institute for Brain Research
2022-2024

Capital Medical University
2022-2024

Background: Parkinson's disease (PD) represents a prevalent neurodegenerative condition that leads to significant disability and contributes growing public health challenge worldwide. However, comprehensive report on progress from 1990 2021 is still lacking, especially regarding the risk factors associated with PD by gender age. This study aims examine patterns of incidence, mortality rates, disability-adjusted life years (DALYs) across all age groups, along linked PD-related fatalities,...

10.2139/ssrn.5085563 preprint EN 2025-01-01

Selective endovascular hypothermia has been used to provide cooling-induced cerebral neuroprotection, but current catheters do not support thermally-insulated transfer of cold infusate, which results in an increased exit temperature, causes hemodilution, and limits its cooling efficiency. Herein, air-sprayed fibroin/silica-based coatings combined with chemical vapor deposited parylene-C capping film was prepared on catheter. This coating features dual-sized-hollow-microparticle incorporated...

10.1016/j.bioactmat.2023.02.022 article EN cc-by-nc-nd Bioactive Materials 2023-02-25

Abstract Aim Recent studies have extensively investigated hypothermia as a therapeutic approach for mitigating neural damage. Despite this, bibliometric analyses specifically focusing on this area remain scarce. Consequently, study aims to comprehensively outline the historical framework of research and pinpoint future directions trends. Methods Articles spanning from 2003 2023, relevant both “neuroprotection” “hypothermia”, were sourced Web Science Core Collection. The CiteSpace software...

10.1111/cns.14795 article EN cc-by CNS Neuroscience & Therapeutics 2024-06-01

Achieving long-lasting hypothermia neuroprotection against reperfusion injury in patients with acute ischemic stroke (AIS) by using intra-arterial selective cooling infusion autologous blood (IA-SCAI) is promising. However, due to the lack of a specialized medical circulatory perfusion system matching cerebral flow characteristics, we conduct translational study an extracorporeal circulation for continuous and controllable brain optimized heat exchanger (BHE). In contrast commercial BHEs,...

10.1016/j.xcrp.2024.102029 article EN cc-by-nc Cell Reports Physical Science 2024-06-01

The neuroprotection of acute ischemic stroke patients can be achieved by intra-arterial selective cooling infusion using cold saline, which decrease brain temperature without influencing the body core temperature. This approach lead to high burdens on heart and decreased hematocrit in scenario loading a amount liquid for longtime usage. Therefore, autologous blood is utilized as perfusate circumvent those side effects.

10.1111/cns.13883 article EN cc-by CNS Neuroscience & Therapeutics 2022-06-15

Brain temperature, a crucial yet under-researched neurophysiological parameter, is governed by the equilibrium between cerebral oxygen metabolism and hemodynamics. Therapeutic hypothermia has been demonstrated as an effective intervention for acute brain injuries, enhancing survival rates prognosis. The success of this treatment hinges on precise regulation temperature. However, absence comprehensive temperature monitoring methods during therapy, combined with limited understanding human...

10.1177/0271678x241270485 article EN Journal of Cerebral Blood Flow & Metabolism 2024-08-11

Neuroprotection plays an important role in the treatment of brain disorders. In recent years, studies using rat models and clinical trials have demonstrated positive effects hydrogen on neurological disorders injuries. Hence, it is great significance to shed light this issue. article, CiteSpace employed for visualization bibliometric analysis research frontiers evolving trends related neuroprotective effect hydrogen.

10.4103/bc.bc_111_23 article EN cc-by-nc-sa Brain Circulation 2024-07-01

With the increasing demand to study cause of complex diseases, mega cohort has gradually replaced traditional small sample and become hotspot epidemiological research. Follow-up is essential step in a obtain information about onset death migration or loss follow-up cases. Its quality direct impact on conclusions study. Therefore, it necessary develop reasonable monitoring program for cohort.In this paper, we summarized contents methods cohorts at home abroad, which aimed provide suggestions...

10.3760/cma.j.cn112338-20210221-00132 article EN PubMed 2022-01-10
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