A5090281379- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
Universidade Federal de Santa Catarina
2016-2017
Creative Research Enterprises (United States)
2016
To investigate the prognostic significance of thyroid hormone profile in patients hospitalized for decompensated cirrhosis.
AIM:To investigate the prognostic significance of insulin-like growth factor-binding protein 3 (IGFBP-3) in patients with cirrhosis. METHODS:Prospective study that included two cohorts: outpatients stable cirrhosis (n = 138) and hospitalized for acute decompensation 189).Development complications, mortality or liver transplantation was assessed by periodical phone calls during outpatient visits.The cohort also underwent clinical laboratory evaluation yearly (2013 2014) predefined visits.In...
IGF-I serum levels are suppressed in cirrhosis, but its prognostic significance is unknown.To investigate the value of patients admitted for acute decompensation cirrhosis.Cohort study that included 103 patients. was measured by enzyme-linked immunosorbent assay (ELISA).Ninety-day mortality 26.2% and it independently associated with MELD, age IGF-I. The Kaplan-Meier survival probability at 90 days 94.3% ≥13 ng/mL 63.2% <13 (p = .001).IGF-I cirrhosis.