A5085568945- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Epigenetics and DNA Methylation
- RNA regulation and disease
- Cytomegalovirus and herpesvirus research
- Psychosomatic Disorders and Their Treatments
- Medicinal Plants and Neuroprotection
- Olfactory and Sensory Function Studies
- Herpesvirus Infections and Treatments
Umeå University
2022-2024
Background The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms reduced health-related quality life (HRQoL) in relation functional exercise capacity, 6 months infection, explored risk factors for sequalae. Methods This was prospective, multicenter, cohort study including 434 patients. At months, physical capacity assessed by 1-minute sit-to-stand test (1MSTST) were...
The mechanisms underlying Post COVID-19 condition (PCC), with its range of long-lasting symptoms, remain unclear. This study investigates DNA methylation patterns over one year in a subset non-hospitalized patients persistent symptoms and reduced quality life, termed PCC+ (Post plus). In cohort 22 individuals matched convalescents (PCC-), we identified distinct differences between the groups that diminish time. Methylation changes TXNRD1 gene were significantly associated cognitive fatigue,...
Abstract Background Olfactory dysfunction together with neurological and cognitive symptoms are common after COVID‐19. We aimed to study whether performance on olfactory neuropsychological tests following infection predict post‐COVID condition (PCC), persisting symptoms, reduced health‐related quality of life. Methods Both hospitalized (N = 10) non‐hospitalized individuals 56) were enrolled in this prospective cohort study. Participants evaluated 1–3 months an threshold test tests, which was...
Background: The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms reduced health-related quality life (HRQoL) in relation functional exercise capacity, six months infection, explored risk factors for sequalae.Methods: This was prospective, multicentre, cohort study including 434 patients. At 6 months, physical capacity assessed by 1-minute sit-to-stand test (1MSTST)...