A5102172773- Coastal and Marine Management
- RNA Research and Splicing
- RNA modifications and cancer
- Coral and Marine Ecosystems Studies
- International Maritime Law Issues
- Neurogenetic and Muscular Disorders Research
- Genomic variations and chromosomal abnormalities
- Plant and Fungal Interactions Research
- Land Use and Ecosystem Services
- Plant Virus Research Studies
- Coastal wetland ecosystem dynamics
- Muscle Physiology and Disorders
- Renal and Vascular Pathologies
- Congenital heart defects research
- Hydraulic and Pneumatic Systems
- Hereditary Neurological Disorders
- Genetics and Neurodevelopmental Disorders
- Cellular transport and secretion
- Cruise Tourism Development and Management
- Chromosomal and Genetic Variations
- Seismic Imaging and Inversion Techniques
- Sexual Differentiation and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Electric and Hybrid Vehicle Technologies
- Disaster Management and Resilience
Qingdao University
2025
Fujian Institute of Oceanography
2019-2024
Ministry of Natural Resources
2019-2024
Xiamen University of Technology
2024
Foshan University
2024
Fujian Medical University
2016-2024
First Affiliated Hospital of Wannan Medical College
2024
Xiamen University
2011-2023
Institute of Plant Protection
2015
Sichuan University
2014
Abstract Background Paraquat (PQ) is a widely used and highly toxic herbicide that poses significant risk to human health. The main consequence of PQ poisoning pulmonary fibrosis, which can result in respiratory failure potentially death. Our research aims uncover crucial mechanism induces senescence epithelial cells, ultimately regulating the activation fibroblasts through exosomal pathway. Methods Cellular was determined by immunohistochemistry SA-β-Gal staining. expression miRNAs measured...
Use of synthetic data has provided a potential solution for addressing unavailable or insufficient training samples in deep learning-based magnetic resonance imaging (MRI). However, the challenge brought by domain gap between and real is usually encountered, especially under complex experimental conditions. In this study, combining Bloch simulation general MRI models, we propose framework lack supervised learning scenarios, termed MOST-DL. A challenging application demonstrated to verify...
The effectiveness of the energy management strategy directly impacts overall system performance a vehicle, particularly under various driving modes. This paper proposes novel electrically-powered hydraulic vehicle that integrates transmission with an electric powertrain. A rule-based is developed to validate feasibility through steady-state simulation. To enhance performance, Random Forest and gradient boosting tree algorithms are employed for velocity feature dimensionality reduction, while...
Abstract Background Coastal wetlands with high biodiversity and productivity provide essential ecosystem services that have a significant positive socio-economic impact. However, coastal reclamation, pollution, climate change are threatening wetlands. Thus, it is critical to identify priority areas for restoration improve habitat resilience adapt environmental changes. Here, we propose general analysis framework integrating nature-based solutions (NbS) into increase multiple stressors in...
As the land–sea interface, coastal zone has become an increasingly key life-support system. However, it is also highly threatened by exposure to both ocean- and land-based human activities. The interdependencies of land sea systems require integration spatial planning achieve sustainable development zones. There are different forms management globally. Whether a form can positively impact how institutional settings affect outcomes need further explanation. Therefore, this study explores...
Duchenne muscular dystrophy (DMD) is typically caused by disrupting the reading frame of dystrophin gene: approximately 70%-80% mutational events are represented deletions or duplications one more exons in gene, and remaining cases subtle mutations, including point small indels, inversions, complex rearrangements. The gene largest known with highest rates new mutations.Deletions were detected DMD proband using multiple ligation-dependent probe amplification (MLPA). Targeted next-generation...
To screen for mutations in the neurotrophic tyrosine kinase receptor type 1 (NTRK1) gene a Chinese family affected with congenital insensitivity to pain anhidrosis (CIPA).With informed consent obtained, peripheral blood samples were obtained from patient and his members. Seventeen coding exons intron-exon boundaries of NTRK1 amplified PCR analyzed by direct sequencing.A novel mutation c.2086_2087insC (p.Arg696 fsx) was identified exon 16 proband. This insertion has caused open reading frame...
To perform mutation analysis and describe the genotype of SMN gene in a patient with spinal muscular atrophy (SMA) his family.Deletion SMN1 exon 7 by conventional PCR-restriction fragment length polymorphism (RFLP) allele-specific PCR, dosage SMN2 multiplex ligation-dependent probe amplification (MLPA) were performed for parents; reverse transcriptase (RT)-PCR sequencing patient. determine whether variant was exclusive to transcripts derived from SMN1, RT-PCR product subcloned multiple...
Planning and zoning of marine areas is a common practice worldwide. In China, major function-oriented (MMFOZ) an effective geographical method for ensuring sustainable resource ecosystems development; however, ecosystem-based management (EBM) has neither been considered in MMFOZ research nor practice. Thus, the current evaluation system does not consider integration between terrestrial components, administrative boundaries are adopted as those spatial units. Here, improved framework...
According to the 2017 results of Special Inspector Sea Reclamation, a substantial number idle reclamation zones existed in 11 provinces (cities) along coast China. To improve protection level coastal wetlands and strictly control activities, it is necessary carry out ecological restoration projects adjacent marine ecosystems. The characteristics Guanghai Bay its project are typical China’s areas, making an optimal representative site for this study. dissipative structure entropy theory was...
Disaster prevention and reduction is imperative for the sustainability of social development. With global economic growth, improving resilience societies to natural hazards has attracted great attention, which effectively reduced losses caused by hazards. However, income inequity as side effect growth also becoming prevalent within many regions around globe, can have a significant role in vulnerability This study analyzed links between inequality direct from storm surge disasters 11 coastal...
Agricultural internet platforms are gaining greater attention from the research community and industrial professionals.The majority of starts technical approaches, while seldom relevant primary study was found about evaluating how well those agriculture perform.This uses multi-dimension measures builds a theoretical framework for agricultural platform evaluation.The mission this is to address benefits Internet on enterprises.Five indicators, namely strategic design ability, user...
Marine functional zoning (MFZ) is a type of marine spatial planning (MSP) implemented widely in China and one the three major systems defined Law PRC on Administration Sea Area Use. adopts “top-down management” for MFZ, which upper management levels impose clear constraints restrictions lower levels. However, this approach has led to issues, such as rigid MFZ classification system unreasonable re-allocation control indicators process assigning at different In study, we propose demonstrate...
To delineate the origins of small supernumerary marker chromosomes (sSMCs) identified in 4 infertile males.The sSMCs were analyzed with combined G-banding, N-banding, multiplex ligation-dependent probe amplification (MLPA), fluorescence situ hybridization (FISH) and single nucleotide polymorphisms array (SNP-array) techniques.G-banding analysis has suggested a 46,X,-Y,+mar karyotype all cases. N-banding revealed that have possessed two satellites located on both sides. By MLPA, 1 patient...
To delineate the structure of Y chromosome aberrations and recombinant mechanisms for three patients.Karyotype analysis, multiplex ligation dependent probe amplification (MLPA), fluorescence in situ hybridization (FISH), sequence tagged sites (STS) human whole genome-wide SNP array were used.The karyotypes patients 46, X, +mar. As suggested by MLPA case 1 has increased copy numbers SRY, ZFY UTY genes, 2 had copies SRY deletion gene, 3 decreased subtelomeric regions X/Yp X/Yq. By STSs...