A5074575443- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Cancer Mechanisms and Therapy
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Medicinal Plant Pharmacodynamics Research
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Flavonoids in Medical Research
- Liver Disease Diagnosis and Treatment
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Pharmacological Effects of Natural Compounds
- Diet and metabolism studies
- Computational Drug Discovery Methods
- Ginseng Biological Effects and Applications
Nanjing University of Chinese Medicine
2022-2024
Myocardial ischemia (MI) is a significant contributor to ischemic heart diseases like angina pectoris and myocardial infarction. Reactive oxygen species produced during MI can trigger lipid peroxidation, damaging cell structure function. Salvia miltiorrhiza (SM) has been widely used clinically in the treatment of cardiovascular diseases. However, process rooting, aboveground parts this plant are usually discarded by tons. To make better use these resources, phenolic acids extracted purified...
Introduction: Bear bile powder (BBP) is widely used in the clinic and has a hypoglycemic effect, but its mechanism not clear. Methods: In this study, type 2 diabetes mellitus (T2DM) rats induced by high-sugar high-fat diet combined with streptozotocin were given BBP, biochemical indexes, pathological sections, metabonomics, intestinal microbiota (IM) short-chain fatty acids (SCFAs) determined. Results: The results showed that BBP could reduce blood glucose, relieve inflammation, insulin...
Although the Bushen Huoxue (BSHX) recipe is commonly used for effective treatment of prethrombotic state recurrent abortions, its mechanism action unclear. In this article, we investigated therapeutic effects BSHX on anti-cardiolipin antibody (ACA) positive miscarriage mice and molecular involved in ACA-positive miscarriages based PI3K-Akt signaling pathway, to provide a scientific basis clinical practice.An mouse model normal pregnancy were adopted experiment. Seventy CBA/J female induced...
Xianlian Jiedu Decoction (XLJDD) is a clinical effective prescription for the treatment of colorectal cancer (CRC) several decades. However, mechanism and targets action XLJDD are still unclear. This study aims to discover pharmacological by employing combination network pharmacology, molecular docking in vitro vivo experimental validation. Multiple databases, including TCMSP, Swiss Target Prediction, Drugbank, Geencards, Malacards, Therapeutic Database (TTD) Disgenet, were searched...
Ethnopharmacological relevance: Xianlian jiedu decoction (XLJDD) is an effective traditional Chinese medicine formula that has been used in the treatment of colorectal cancer (CRC) for several decades. But now it still incomplete understanding role XLJDD cancer.Aim studyThis study aimed to evaluate anti-tumor effect on CT-26 tumor-bearing mice, explore its possible mechanism and analyze potential active ingredients.Materials methods: In vivo, anti-cancer effects factions was evaluated by...