Seung-Hyun Kim

ORCID: 0009-0001-5450-5245
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About
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Research Areas
  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • Infrastructure Maintenance and Monitoring
  • Renal and related cancers
  • Vehicle emissions and performance
  • Traffic Prediction and Management Techniques
  • Virus-based gene therapy research
  • Retinal Development and Disorders

Korea Research Institute of Bioscience and Biotechnology
2024-2025

With recent advances in adeno-associated virus (AAV)-based gene therapy, efficacy and toxicity screening have become essential for developing therapeutic drugs retinal diseases. Retinal organoids from human pluripotent stem cells (hPSCs) offer a more accessible reproducible test platform evaluating AAV-based therapy. In this study, hPSCs were differentiated into composed of various types cells. The transduction efficiencies AAV2 AAV8, which are widely used clinical trials inherited diseases,...

10.15283/ijsc23071 article EN International Journal of Stem Cells 2024-01-22

오늘날 우리 주변에는 규모를 가늠할 수 없을 정도로 많은 정보와 데이터가 생산되는 '빅데이터(Big Data)'의 시대가 도래 하였으며, 그 중요성이 날로 커지고 있다. 교통분야에서는 전통적인 통행기반교통모형(Trip-Based Model)인 4단계 교통수요추정법의 한계가 드러나고 있으며, 활동기반교통모형(Activity-Based Model...

10.12815/kits.2016.15.4.044 article KO The Journal of The Korea Institute of Intelligent Transport Systems 2016-08-31
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