A5101985747- Ovarian cancer diagnosis and treatment
- Ferroptosis and cancer prognosis
- Pharmacological Effects of Natural Compounds
- Quinazolinone synthesis and applications
- Cancer Cells and Metastasis
- High Altitude and Hypoxia
- RNA modifications and cancer
- PARP inhibition in cancer therapy
- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- Metabolomics and Mass Spectrometry Studies
- Synthesis of Organic Compounds
- Circular RNAs in diseases
Hebei Medical University
2022-2024
Fourth Hospital of Hebei Medical University
2022-2024
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2023
First Hospital of Qinhuangdao
2022
Ovarian cancer (OC) is the most common gynecological malignancy worldwide, and chemoresistance occurs in patients, resulting treatment failure. A better understanding of molecular processes underlying drug resistance crucial for development efficient therapies to improve OC patient outcomes. Circular RNAs (circRNAs) ferroptosis play roles tumorigenesis chemotherapy. However, little known about role(s) circRNAs regulating OC. To gain insights into cisplatin OC, we studied...
Ovarian cancer (OC) is one of the common gynecological malignant tumors. Cell division cycle-associated protein-3 (CDCA3) involved in regulation cell cycle progression. The role CDCA3 OC was explored this study.The expression evaluated Gene Expression Omnibus (GEO) database and further verified by qRT-PCR Western blot (WB). Subsequently, we established lentivirus-mediated knockdown lines HO-8910 A2780. biological roles on proliferation, sensitivity to cisplatin, apoptosis, migration tumor...
Evodia rutaecarpa (ER) is a well-known herbal Chinese medicine traditionally used for analgesia in dysmenorrhea, headaches, abdominal pain, etc. Notably, the analgesic effect of wine-processed (PER) was more potent than that raw ER. This research aimed to investigate mechanism and pharmacodynamic substance basis ER PER on smooth muscle cells dysmenorrhea mice. Metabolomics methods based UPLC-Q-TOF-MS were utilized analyse differential components before after wine processing. Afterwards,...