A5031592825- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Neurological Complications and Syndromes
- Nitric Oxide and Endothelin Effects
- Renal Diseases and Glomerulopathies
- Xenotransplantation and immune response
- Urinary Bladder and Prostate Research
- Autoimmune and Inflammatory Disorders Research
- Oral and gingival health research
- Blood Coagulation and Thrombosis Mechanisms
- Transplantation: Methods and Outcomes
- Pregnancy and Medication Impact
- Adolescent and Pediatric Healthcare
- Blood groups and transfusion
- Multiferroics and related materials
- Tissue Engineering and Regenerative Medicine
- Urological Disorders and Treatments
- Aortic aneurysm repair treatments
- Cytomegalovirus and herpesvirus research
- Abdominal vascular conditions and treatments
- Renal and Vascular Pathologies
- HIV/AIDS drug development and treatment
- Renin-Angiotensin System Studies
- Ion Transport and Channel Regulation
Niigata University
2007-2024
The mechanism of long-term B cell immunity against donor blood group antigens in recipients who undergo ABO-incompatible (ABOi) living-donor kidney transplantation (LKTx) is unknown. To address this question, we evaluated serial anti-A and anti-B antibody titers 50 adult recipients. Donor-specific remained low (≤1:4) 42 (84%). However, antibodies nondonor were continuously produced with type O. We stimulated recipients' peripheral mononuclear cells vitro to investigate whether the absence...
The phenomenon of accommodation in recipients blood group ABO incompatible kidney transplantation (iKTx), which grafts survive despite the presence A or B antigen graft and corresponding antibodies recipient’s blood, is not uncommon. α1,3-N-Acetylgalactosaminyltransferase α1,3galactosyltransferase associated with synthesis (A enzymes), respectively, were measured by a highly specific enzyme-linked immunosorbent assay sera transplanted tissues patients who underwent an iKTx. Allogeneic...
<b>Objective:</b> The lymphocyte immunosuppressant sensitivity test has been used to predict the pharmacodynamics of immunosuppressive drugs for purpose preventing acute rejection and infection after renal transplantation. On other hand, measuring ATP levels in peripheral CD4+ lymphocytes is also able monitor risks transplant recipients. In present study, we examined relationship between mycophenolic acid before <b>Methods:</b> We both pharmacological efficacy 2, 4 6 weeks operation 20...
Contrary to partially substituted systems, WO3 molecular sieves that exclusively comprise a d0 transition metal ion and do not possess template ions in the cavity are new class of materials for photocatalysis owing their framework structure. Because thermodynamically lacks proton-reduction capability, exploring diverse synthetic approaches other is desirable facilitating utilization as H2 evolution water splitting systems. Herein, we report an efficient approach protonation Ag2Ta4O11 afford...
Solid-state reaction (SSR) is a widely adopted method for functional inorganic material syntheses. Unlike intricate systems emerging from chemically unstable precursor usage, the SSR can proceed stable couples using simple apparatuses. However, this associated with high temperatures that overcome solid-state diffusion. Moreover, syntheses of technologically crucial carbides lead to greenhouse gas emissions. Therefore, exploring an extrinsic component suppress these challenges vital...
Introduction: Since the first successful in January 1989, we have performed more than 2,400 ABO incompatible kidney transplantation(ABOIKT) to date.and it accounts for 30% of annual living transplants Japan. Purpose this study: From latest registry, reviewed long term patient and graft survival, analysed factors which affected outcome. Patients Methods: 2,434 cases were enrolled study. Observation period was median 3 years 5 months( 1 day 23 7 months) Average recipient age 43.7 years. Blood...
A66 Background: Reducing calcineurin-inhibitor-induced nephrotoxicity and simultaneously avoiding long-term steroid side-effects is a desirable goal in renal transplantation. We examined the hypothesis that using Basiliximab (Simulect) mycophenolate mofetil (MMF) would allow lowering of target pre-dose blood concentrations calcineurin-inhibitor (cyclosporine or tacrolimus) immediately after transplantation, early withdrawal steroids Methods: Fifty-eight kidney recipients (first second with...
An experimental reconstruction of the urinary bladder using specially designed bovine cross linked atelocollagen sponge was performed after partial cystectomy in 12 male rabbits. Bladder with hybrid type biomaterials both atelocollage and cultured autologous cells were 5 rabbits (the 1st group). The collected from mucosa muscular layer seeded on before reconstruction. Reconstruction without other 7 2nd In 9 these rabbits, successfully implanted native bladder. Histopathological findings...
Abstract: We present here a male patient who had developed nephrotic syndrome 11 yr after kidney transplantation. Nephrotic suddenly occurred severe sunburn he got in Hawaii. Such clinical course seemed very rare transplantation, and multifactorial etiology was suspected. The histological findings of graft biopsy were intricate. On light microscopy, there mesangial expansion endocapillary proliferation with duplication GBM crescent formation. Deposits IgM mesangium the most prominent finding...
Tasaki, M.1; Yazawa, S.2; Nakajima, T.3; Imai, N.4; Nakagawa, Y.5; Saito, K.1; Takahashi, K.1 Author Information
Division of Urology, Department Regenerative And Transplant Medicine, Graduate School Medical Dental Sciences, Niigata University
To indicate renal disorders and to predict the prognosis of function, we investigated significance endothelin-I (ET-1) in retained urine, which was collected at relief urinary tract obstruction 20 congenital hydronephrotic patients. Urinary ET-1 level ranged from 15 1411 pg/mg creatinine (Cr), higher than normal Subjects many cases. The value showed a positive correlation with N-acetyl-β-Dglucosaminidase (U/gCr) (r=0.663, p < 0.01) β-2-microglobulin (μg/mgCr) (r=0.486, 0.05). There no...
Tc99m-dimercaptosuccinic acid renal uptake (DMSA uptake) was examined to assess the changes in split function following percutaneous transluminal angioplasty (PTRA) 9 patients with a total of 12 artery stenoses and renovascular hypertension (RVH). The results were studied respect age, degree stenosis, vein renin ratio (RVRR) before PTRA. Although systolic blood pressure, peripheral plasma activity improved 3 months after PTRA, neither DMSA affected kidneys nor that contralateral improved....