Kate B. Fitzpatrick
- Plant Molecular Biology Research
- Neurobiology and Insect Physiology Research
- Fungal Infections and Studies
- Insect Resistance and Genetics
- Advanced biosensing and bioanalysis techniques
- DNA Repair Mechanisms
- Insect and Arachnid Ecology and Behavior
- RNA and protein synthesis mechanisms
- RNA Interference and Gene Delivery
- Plant Disease Resistance and Genetics
Brandeis University
2024-2025
Phillips Exeter Academy
2019
SFM4-3, KOD DGLNK, and Therminator polymerase are investigated for their compatibility with SELection Modified Aptamers (SELMA), an aptamer discovery method that enables incorporation of large nucleobase modifications such as glycans.
Binary expression systems like the LexA-LexAop system provide a powerful experimental tool kit to study gene and tissue function in developmental biology, neurobiology, physiology. However, number of well-defined LexA enhancer trap insertions remains limited. In this study, we present molecular characterization initial analysis nearly 100 novel StanEx traps, derived from
<title>Abstract</title> Using budding yeast, <italic>S cerevisiae</italic>, we show that Arp2/3 actin branching complex has an evolutionarily conserved role in promoting chromosome mobility of double-strand breaks (DSBs). Disrupting activity after DSB induction, by drug treatment with CK-666 or auxin-induced degron depletion nucleation factors Las17<sup>WASP</sup> the type-1 myosins (Myo3 and Myo5), markedly reduced radius confinement DSBs. was found to be required initiate maintain 5’to 3’...
Abstract Binary expression systems like the LexA-LexAop system provide a powerful experimental tool kit to study gene and tissue function in developmental biology, neurobiology physiology. However, number of well-defined LexA enhancer trap insertions remains limited. In this study, we present molecular characterization initial analysis nearly 100 novel StanEx traps, derived from StonEx 1 index line. This includes 76 into novel, distinct loci not previously associated with traps or targeted...