Kate B. Fitzpatrick

ORCID: 0009-0002-4389-1969
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Neurobiology and Insect Physiology Research
  • Fungal Infections and Studies
  • Insect Resistance and Genetics
  • Advanced biosensing and bioanalysis techniques
  • DNA Repair Mechanisms
  • Insect and Arachnid Ecology and Behavior
  • RNA and protein synthesis mechanisms
  • RNA Interference and Gene Delivery
  • Plant Disease Resistance and Genetics

Brandeis University
2024-2025

Phillips Exeter Academy
2019

SFM4-3, KOD DGLNK, and Therminator polymerase are investigated for their compatibility with SELection Modified Aptamers (SELMA), an aptamer discovery method that enables incorporation of large nucleobase modifications such as glycans.

10.1039/d4ob01505c article EN cc-by-nc Organic & Biomolecular Chemistry 2025-01-01

Binary expression systems like the LexA-LexAop system provide a powerful experimental tool kit to study gene and tissue function in developmental biology, neurobiology, physiology. However, number of well-defined LexA enhancer trap insertions remains limited. In this study, we present molecular characterization initial analysis nearly 100 novel StanEx traps, derived from

10.1534/g3.119.400105 article EN cc-by G3 Genes Genomes Genetics 2019-05-01

<title>Abstract</title> Using budding yeast, <italic>S cerevisiae</italic>, we show that Arp2/3 actin branching complex has an evolutionarily conserved role in promoting chromosome mobility of double-strand breaks (DSBs). Disrupting activity after DSB induction, by drug treatment with CK-666 or auxin-induced degron depletion nucleation factors Las17<sup>WASP</sup> the type-1 myosins (Myo3 and Myo5), markedly reduced radius confinement DSBs. was found to be required initiate maintain 5’to 3’...

10.21203/rs.3.rs-5125308/v1 preprint EN cc-by Research Square (Research Square) 2024-10-07

Abstract Binary expression systems like the LexA-LexAop system provide a powerful experimental tool kit to study gene and tissue function in developmental biology, neurobiology physiology. However, number of well-defined LexA enhancer trap insertions remains limited. In this study, we present molecular characterization initial analysis nearly 100 novel StanEx traps, derived from StonEx 1 index line. This includes 76 into novel, distinct loci not previously associated with traps or targeted...

10.1101/552513 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-02-16
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