Yuan Ma

ORCID: 0009-0002-5040-0339
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Microbial Metabolic Engineering and Bioproduction
  • Medical Research and Treatments
  • Glycosylation and Glycoproteins Research
  • SARS-CoV-2 detection and testing
  • Viral Infections and Outbreaks Research
  • RNA and protein synthesis mechanisms
  • Health Promotion and Cardiovascular Prevention
  • Intergenerational Family Dynamics and Caregiving
  • Biofuel production and bioconversion
  • Health and Wellbeing Research
  • CRISPR and Genetic Engineering

Tianjin University
2024-2025

Nanjing Medical University
2021

Jiangsu Province Hospital
2021

National Institute for Communicable Disease Control and Prevention
2020

Abstract Synthetic biology confers new functions to hosts by introducing exogenous genetic elements, yet rebuilding complex traits that are based on large-scale information remains challenging. Here, we developed a CRISPR/Cas9-mediated haploidization method bypasses the natural process of meiosis. Based programmed in yeast, further an easy-to-use designated HAnDy (Haploidization-based DNA Assembly and Delivery yeast) enables efficient assembly delivery large DNA, with no need for any fussy...

10.1038/s41422-024-00934-3 article EN cc-by Cell Research 2024-02-08

The site-specific recombination system is a versatile tool in genome engineering, enabling controlled DNA inversion or deletion at specific sites to generate genetic diversity. multiplexed system, which preferentially facilitates reverse-oriented rather than same-oriented sites, has not been found eukaryotes. Here, we establish Rci51-5/multi-sfxa101, yeast. Firstly, develop high-throughput screening based on the on/off transcriptional control of multiple markers by inversion. After two...

10.1038/s41467-025-57206-w article EN cc-by-nc-nd Nature Communications 2025-02-24

Objective To learn current status of health management services in the elderly individuals living rural areas Beijing, so as to provide evidence for healthcare improvement. Methods The residents aged 60 or above from several districts Beijing were selected by using multistage random sampling method January 2013. The programme those participants obtained and their satisfactory scale evaluated. Results A total 719 1 023(71.3%)individuals had check-up over past years. Only 4...

10.3760/cma.j.issn.1674-0815.2014.01.010 article EN Chin J Health Manage 2014-02-20

Objective To understand current status and influencing factors of long-term care for elderly people who lived in rural areas Beijing. Methods A total 1022 people(age>60 years old)were enrolled this cross-sectional study during December,2012 January, 2013. Demographic information, health needs intent to were learned through a questionaire survey. Chi-square test multiple non-conditional logistic regression analysis used identify the that related respondents'...

10.3760/cma.j.issn.1674-0815.2013.06.003 article EN Chin J Health Manage 2013-12-20

World Standards Day was established by the International Organization for Standardization (ISO) on October 14 to enhance awareness significance of international standardization respond needs businesses, industries, governments and consumers worldwide.Since its rejoining ISO in 1978, China held various presentations, symposiums, commemorative events major medium-sized cities nationwide publicize role societal development among people.The theme 51st this year is "Protecting planet with...

10.46234/ccdcw2020.221 article EN China CDC Weekly 2020-01-01

Abstract Background : Although recurring cases of COVID-19 have been sporadically reported, the long-persistence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still arguable. We aimed to provide evidences recovered patients with long-lasting positive SARS-CoV-2 RNA tests in a Chinese hospital. Case presentations reported 4 discharged relapsed during period self-quarantine, leading an extended disease course. All four were historically healthy without known underlying...

10.21203/rs.3.rs-354369/v1 preprint EN cc-by Research Square (Research Square) 2021-03-31
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