Yu Cai

ORCID: 0009-0002-6569-2581
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About
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Research Areas
  • Advancements in Transdermal Drug Delivery
  • Advanced Drug Delivery Systems
  • Hydrogels: synthesis, properties, applications
  • Biosensors and Analytical Detection
  • Advanced Polymer Synthesis and Characterization
  • Advanced Biosensing Techniques and Applications
  • Advanced biosensing and bioanalysis techniques
  • Surgical Sutures and Adhesives
  • Phytochemistry and Biological Activities
  • Drug Solubulity and Delivery Systems
  • Flavonoids in Medical Research
  • Analytical chemistry methods development
  • Bee Products Chemical Analysis
  • Drug Transport and Resistance Mechanisms
  • Image Processing and 3D Reconstruction
  • Microfluidic and Capillary Electrophoresis Applications
  • Drug-Induced Hepatotoxicity and Protection
  • Analytical Methods in Pharmaceuticals
  • Renal function and acid-base balance
  • Natural product bioactivities and synthesis
  • Essential Oils and Antimicrobial Activity
  • Antibiotics Pharmacokinetics and Efficacy
  • Microfluidic and Bio-sensing Technologies
  • biodegradable polymer synthesis and properties
  • Traditional Chinese Medicine Analysis

Yanbian University
2021-2024

Shenyang Pharmaceutical University
2022

Northeastern University
2018-2020

Division of Chemistry
2018

Northeastern University
2018

University of Macau
2015

Zen-Noh (Japan)
2013

Zhongshan Hospital
2012

This study introduces a dendronized pressure-sensitive adhesive, TMPE@Rha, addressing Food and Drug Administration (FDA) concerns about traditional adhesives (PSAs) in transdermal drug delivery systems. The unique formulation, composed of rhamnose, trihydroxypropane, poly(ethylene glycol), significantly enhances cohesion tissue adhesion. Leveraging rhamnose improves intermolecular interactions surface chain mobility, boosting Compared to acrylic adhesive 87-DT-4098, TMPE@Rha shows...

10.1021/acsami.3c17363 article EN ACS Applied Materials & Interfaces 2024-02-21

In transdermal patches, pressure-sensitive adhesives (PSAs) are considered the most critical excipients due to their ability provide adhesion and act as a drug reservoir. However, loaded drugs plasticize resulting in cold flow phenomenon, which poses product safety risk reduces treatment efficacy. Herein, 3-methacryloxypropyltrimethoxysilane (KH-570)-modified hydroxyl acrylate PSA (AAOK) was proposed. Diclofenac, ketoprofen, tulobuterol, oxybutynin were selected model drugs. The results...

10.1021/acsapm.3c03208 article EN ACS Applied Polymer Materials 2024-02-19

A sensitive detection method combined with an effective on-line concentration may improve the analytical performance of a paper-based device (PAD), and its merits low cost portability in POCT are fully demonstrated. Here, PAD system chemiluminescence (CL) electrokinetic preconcentration was introduced, demonstrated by hemin. commercially available miniaturized optical module used for CL detection. Firstly, hemin stacked on simple paper fluidic channel based field amplified stacking (FAS),...

10.1039/c8an01859f article EN The Analyst 2018-11-06
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