A5066514427- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Reproductive tract infections research
- Ethics in Clinical Research
- Syphilis Diagnosis and Treatment
- Mental Health and Patient Involvement
- Digital Mental Health Interventions
- Patient-Provider Communication in Healthcare
Biomedical Research and Training Institute
2022-2025
London School of Hygiene & Tropical Medicine
2023
Introduction Obtaining informed consent for research includes the use of information sheets, which are often long and may be difficult participants to understand. We conducted a trial investigate whether procedures using study video coupled with electronic were non-inferior standard participant sheets (PIS) among youth aged 18–24 years in Zimbabwe. Methods The was nested within an endline population-based survey cluster-randomised from October 2021 June 2022. Randomisation or paper-based at...
Background Sepsis is a major cause of mortality in low-resource settings. Effective microbiological culture services are bottleneck diagnosis and surveillance. Aim We aimed to evaluate the performance BIOFIRE FILMARRAY Blood Culture Identification 2 (BCID2, bioMérieux) assay setting laboratory comparison standard practice. Methods This five month prospective validation study included all positive blood cultures collected at Sally Mugabe Central Hospital, Harare, Zimbabwe. BCID2 testing was...
Background Many adolescents and young adults (AYAs; 10–24 years old) are excluded from HIV research because of social, ethical, legal challenges with informed consent, resulting in limited AYA-focused data. We use a participatory approach to identify strategies for improving AYA consent processes low- middle-income countries (LMICs). Methods conducted digital crowdsourcing open call ideas improve LMICs. Crowdsourcing involves engaging group people problem-solving, then sharing emergent...
Young people are at high risk of sexually transmitted infections (STIs). We report STI testing uptake, prevalence and incidence within a community-based integrated HIV sexual reproductive health service for youth, being evaluated in cluster randomised trial Zimbabwe.
Objectives Youth are at high risk of sexually transmitted infections (STIs) in Africa. We aimed to determine the factors for curable STIs youth Zimbabwe. Methods A population-based survey was conducted among randomly selected 18–24 year-olds 16 communities across two provinces Zimbabwe ascertain outcomes a cluster randomised trial investigating impact community-based STI screening on population prevalence STIs. Participants underwent an interviewer-administered questionnaire, HIV testing and...
Young people are at particularly high risk of acquiring sexually transmitted infections (STIs). We conducted a trial to investigate the effect community-based intervention that included STI screening among youth on population-level prevalence STIs in Zimbabwe. STICH was parallel-arm, cluster-randomised controlled nested within CHIEDZA, integrated HIV and sexual reproductive health services for Harare Bulawayo provinces with eight clusters each province, randomised 1:1 control (existing...
Background: Young people are at high risk of sexually transmitted infections (STIs). We report STI testing uptake, prevalence and incidence within a community-based integrated HIV sexual reproductive health service for youth, being evaluated in cluster randomised trial Zimbabwe. Methods: was offered to all attendees (16-24 years) 12 intervention clusters over months. Testing Chlamydia trachomatis [CT] Neisseria gonorrhoeae [NG] males females with results available one week follow-up...
<h3>Background</h3> Sexually transmitted infections (STIs) and bacterial vaginosis (BV) are major risk factors for HIV infection reproductive complications in women living sub-Saharan Africa, part because of inflammation associated with these conditions. In women, most STIs BV asymptomatic, therefore not diagnosed low middle income countries (LMICs), where etiologic testing is common treated based on presence signs or symptoms (syndromic management). To improve STI/BV case finding LMICs, we...
Background: Many adolescents and young adults (AYAs, 10-24 years old) are excluded from HIV research studies because of social, ethical, legal issues related to informed consent requirements, resulting in limited data address their needs. Engaging stakeholders has potential not only for identifying the relevant barriers, but also development compelling AYA-focused strategies improve process AYA low middle-income countries (LMICs) with a higher burden HIV. We use participatory approach...