A5111995963- Global Maternal and Child Health
- Neonatal and Maternal Infections
- Ethics in medical practice
- Viral Infections and Outbreaks Research
- Mobile Health and mHealth Applications
- HIV/AIDS Research and Interventions
- Empathy and Medical Education
- Disaster Response and Management
- Primary Care and Health Outcomes
- COVID-19 Impact on Reproduction
- HIV Research and Treatment
- Sepsis Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Ethics and Legal Issues in Pediatric Healthcare
- Delphi Technique in Research
- Streptococcal Infections and Treatments
- Innovations in Medical Education
- Healthcare cost, quality, practices
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Pneumonia and Respiratory Infections
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Emergency and Acute Care Studies
- Hematological disorders and diagnostics
Imperial College London
2022-2025
St Mary's Hospital
2025
Biomedical Research and Training Institute
2020-2024
Imperial College Healthcare NHS Trust
2024
Royal College of Paediatrics and Child Health
2024
University College London
2013-2023
Great Ormond Street Hospital
2016-2023
University of Science and Technology Beijing
2023
University Hospital of Wales
2021
Institute of Child Health
2021
Reader Survey: Which testing scenarios are low value? Unsustainable rising health care costs in the United States have made reducing while maintaining high-quality a national priority. The overuse of some screening and diagnostic tests is an important component unnecessary costs. More judicious use such will improve quality reflect responsible awareness Efforts to control expenditures should focus not only on benefits, harms, but value tests—meaning assessment whether test provides benefits...
Infection is considered a possible trigger for preterm labour, supported by evidence showing the presence of bacteria in placenta and placental membranes from births. In this study, 16S rDNA pyrosequencing was used to identify membranes. Caesarean sections vaginal deliveries at term were found harbour common genera. Mycoplasma hominis, Aerococcus christensenii, Gardnerella vaginalis Fusobacterium nucleatum either only present or greater abundance than term. These data support previous...
The optimal dose and duration of oral amoxicillin for children with community-acquired pneumonia (CAP) are unclear.To determine whether lower-dose is noninferior to higher 3-day treatment 7 days.Multicenter, randomized, 2 × factorial noninferiority trial enrolling 824 children, aged 6 months older, clinically diagnosed CAP, treated on discharge from emergency departments inpatient wards 28 hospitals in the UK 1 Ireland between February 2017 April 2019, last visit May 21, 2019.Children were...
There has recently been much in both lay and medical literature on the promotion of healthy lifestyles. Once upon a time people did not have lifestyles; they had lives. Those lives were filled with work play, battle respite, excitement boredom, but principally day-to-day struggle for existence, centered largely around family, birth, death, disease, health. What is difference between lifestyle life? Central to it, I believe, concept that something one chooses, life happens one. This...
Five patients with laboratory evidence of latent or neurosyphilis were treated orally doxycycline (200 mg) twice a day for 21 days. After the seventh dose, mean level in serum was 5.8 micrograms/ml, drug cerebrospinal fluid 1.3 micrograms/ml. The penetration into 26%. These preliminary findings suggest that doxycycline, administered at dose 200 mg day, reaches sufficient concentration to be worthy further evaluation as an alternative regimen penicillin therapy neurosyphilis.
During autumn/winter 2022, UK pediatricians reported an unseasonal increase in invasive group A streptococcal infections; a striking proportion presenting with pneumonia parapneumonic effusion.
The Joint Committee on Vaccination and Immunisation (JCVI) has recently recommended the introduction of varicella (chickenpox) vaccine into UK’s routine childhood immunisation schedule. This was previously only available to a small group eligible children or through private healthcare providers. Engaging families in conversations around vaccines is recognised as important for informed decision-making, professionals leading these discussions need be confident well-informed. article aims...
Neonatal sepsis is a major cause of mortality in low-resource settings. We assessed how neonatal guidelines were used two Zimbabwean hospitals and one Malawian hospital. Using routine data collected with the digital health intervention, Neotree, we retrospectively reviewed doctors' nurses' agreement national World Health Organization (WHO) guideline recommendations for antibiotic prescription sepsis. compared clinical features outcomes neonates who should have received antibiotics as per...
Healthcare providers' attitudes toward sexual minorities influence patient comfort and outcomes. This study characterized medical student gay men, focusing on behavior, personhood, civil rights, male toughness. A cross-sectional web-based anonymous survey was sent to students enrolled at the University of California, Davis (N = 371) with a response rate 68%. Few respondents expressed negative men or would deny them rights. More responses were seen respect aspects intimate behavior...
Box 1. Elements to consider when improving health-care quality in resource-poor settings
PCRs have revolutionised the detection of bacteria in clinical samples since their widespread introduction 1990s.1 Quantitative PCR (qPCR), also known as specific PCR, involves targeting particular bacterial species. The technique uses primers (short strands nucleic acid needed to initiate DNA replication) and fluorescent probes allow real-time quantification target during amplification. qPCR assay is a mainstay microbiological diagnostics within National Health Service (NHS). At our...
We describe a case series of 35 Ebola virus disease (EVD) survivors during the epidemic in West Africa who had neurologic and accompanying psychiatric sequelae. Survivors meeting criteria were invited from cohort 361 EVD to attend preliminary clinic. Those whose severe features documented clinic referred for specialist evaluation, ophthalmologic examination, assessment. Of with sequelae, 13 migraine headache, 2 stroke, peripheral sensory neuropathy, nerve lesions. brain computed tomography...
There are 2. 4 million annual neonatal deaths worldwide. Simple, evidence-based interventions such as temperature control could prevent approximately two-thirds of these deaths. However, key problems in implementing a lack newborn-trained healthcare workers and data collection systems. NeoTree is digital platform aiming to improve newborn care low-resource settings through real-time capture feedback alongside education linkage. This project demonstrates proof concept the tool replacing...
Improving peri- and postnatal facility-based care in low-resource settings (LRS) could save over 6000 babies' lives per day. Most of the annual 2.4 million neonatal deaths 2 stillbirths occur healthcare facilities LRS are preventable through implementation cost-effective, simple, evidence-based interventions. However, their is challenging systems where one four babies admitted to units die. In high-resource strengthening increasingly delivered via learning optimise quality, but this approach...
On Being a Doctor5 January 1999CuriosityFREEFaith T. Fitzgerald, MDFaith MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-1-199901050-00015 SectionsAboutVisual AbstractPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail About 15 years ago, when I was dean of students at the University California, Davis, School Medicine, yet another periodic paroxysms “holism” in...
The APACHE-II (acute physiology and chronic health evaluation) severity of disease classification system was used to stratify prognosis granulocytopenic patients with hematologic malignancies. A total 146 admissions were retrospectively reviewed. In 26 ICU admissions, mortality 69.2%; in 120 the ward, 15.8%. score successfully stratified both ward settings. Respiratory failure presence pneumonia on chest x-ray identified as poor prognostic factors. admitted for monitoring or postoperative...
In sub-Saharan Africa, 20%-25% of people starting antiretroviral therapy (ART) have severe immunosuppression; approximately 10% die within 3 months. the Reduction EArly mortaLITY (REALITY) randomized trial, a broad enhanced anti-infection prophylaxis bundle reduced mortality vs cotrimoxazole. We investigate contribution and timing different causes mortality/morbidity.Participants started ART with CD4 count <100 cells/µL; comprised cotrimoxazole plus 12 weeks isoniazid + fluconazole,...
To examine indirect impacts of the COVID-19 pandemic on neonatal care in low-income and middle-income countries. Interrupted time series analysis. Two tertiary units Harare, Zimbabwe Lilongwe, Malawi. We included a total 6800 neonates who were admitted to either unit from 1 June 2019 25 September 2020 (Zimbabwe: 3450; Malawi: 3350). applied no specific exclusion criteria. The first cases each country 20 March 2020; 3 April 2020). Changes number admissions, gestational age birth weight,...