- Signaling Pathways in Disease
- Nerve injury and regeneration
- HIV Research and Treatment
- DNA Repair Mechanisms
- Cell death mechanisms and regulation
- Extracellular vesicles in disease
- Axon Guidance and Neuronal Signaling
- HIV/AIDS drug development and treatment
- Biochemical and Molecular Research
- Peptidase Inhibition and Analysis
- Endoplasmic Reticulum Stress and Disease
- Toxin Mechanisms and Immunotoxins
- Pregnancy and preeclampsia studies
- MicroRNA in disease regulation
Western University
2023-2024
Lawson Health Research Institute
2024
Beth Israel Deaconess Medical Center
2000-2015
Harvard University
2000-2015
Abstract Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally may trigger dementia later in life mothers their offspring. However, etiological drivers remain elusive. Cis P-tau an early driver blood biomarker pre-clinical Alzheimer’s after vascular or traumatic brain injury, which can be targeted by stereo-specific antibody, with clinical trials ongoing. Here we find significant cis placenta serum PE patients, primary human trophoblasts exposed to hypoxia sera from...