A5102604170- Cancer-related molecular mechanisms research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Genetic Associations and Epidemiology
Zhongnan Hospital of Wuhan University
2023-2025
Wuhan University
2023-2025
Abstract Background Cervical cancer (CC) ranks fourth in global incidence and represents the second leading cause of deaths. HPV integration into human genome is a key molecular event progression carcinogenesis. Methods This study utilized high-risk HPV-positive women samples to investigate through high-throughput Viral Integration Detection (HIVID). Subsequently, expression recurrent genes at both mRNA protein level was determined GEIPA, Human Protein Atlas (HPA). Furthermore, prognostic...
Abstract Background Several experimental studies already proved that the increase of total testosterone could lead to development gynecological disease. Animal experiments have shown may be associated with progression cervical cancer (CC). And metabolism cholesterol which serves as initial raw material for synthesis is crucial occurrence CC. However, causal relationship between CC and Total still remained unknown. Methods We performed bidirectional Mendelian randomization (MR) study using...