A5066362361- Antimicrobial agents and applications
- Antimicrobial Peptides and Activities
- Bacterial biofilms and quorum sensing
- Microwave-Assisted Synthesis and Applications
- Photoreceptor and optogenetics research
- Mesoporous Materials and Catalysis
- Biochemical Analysis and Sensing Techniques
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Mechanical and Optical Resonators
- Microwave and Dielectric Measurement Techniques
- Magneto-Optical Properties and Applications
- melanin and skin pigmentation
- Aquaculture Nutrition and Growth
- Plasma Diagnostics and Applications
- Advanced Fiber Optic Sensors
- Rheumatoid Arthritis Research and Therapies
- Leaf Properties and Growth Measurement
- Remote Sensing in Agriculture
- Genetic and phenotypic traits in livestock
- Advanced Thermodynamics and Statistical Mechanics
- Genetics and Plant Breeding
- Molecular Junctions and Nanostructures
- Cancer-related molecular mechanisms research
- Reproductive biology and impacts on aquatic species
- Advanced Physical and Chemical Molecular Interactions
Peking University First Hospital
2024
Taiyuan Central Hospital
2024
Peking University
2024
National University of Singapore
1996-2024
Singapore-MIT Alliance for Research and Technology
2024
China Rural Technology Development Center
2024
Tsinghua University
2024
Sichuan Agricultural University
2024
Hainan University
2021-2023
Macau University of Science and Technology
2021-2022
Biofilms and the rapid evolution of multidrug resistance complicate treatment bacterial infections. Antibiofilm agents such as metallic–inorganic nanoparticles or peptides act by exerting antibacterial effects and, hence, do not combat biofilms antibiotics-resistant strains. In this Letter, we show that block copolymer DA95B5, dextran-block-poly((3-acrylamidopropyl) trimethylammonium chloride (AMPTMA)-co-butyl methacrylate (BMA)), effectively removes preformed various clinically relevant...
Abstract The treatment of bacterial infections is hindered by the presence biofilms and metabolically inactive persisters. Here, we report synthesis an enantiomeric block co-beta-peptide, poly(amido-D-glucose)- -poly(beta-L-lysine), with high yield purity one-shot one-pot anionic-ring opening (co)polymerization. co-beta-peptide bactericidal against methicillin-resistant Staphylococcus aureus (MRSA), including replicating, biofilm persister cells, also disperses biomass. It active towards...
The safety of energy storage devices is increasingly crucial due to the growing requirements for application under harsh conditions. Effective methods enhancing robustness without compromising functionality are necessary. Here we present an impact-resistant, ready-to-use supercapacitor constructed from self-healable hydrogel electrolyte-infused lattice electrodes. Three-dimensional-printed carbon-coated silicon oxycarbide current collectors provide mechanical protection, with compressive...
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of drug-resistant infections. Its propensity to develop biofilms makes it especially resistant conventional antibiotics. We present novel nanoparticle (NP) system made from biocompatible F-127 surfactant, tannic acid (TA), and biguanide-based polymetformin (PMET) (termed FTP NPs), which can kill MRSA biofilm bacteria effectively in vitro vivo has excellent biocompatibility. NPs exhibit bactericidal activity—ability...
Abstract Nanoparticles have been widely used in detection and killing of bacteria; however, targeting bacteria is still challenging. Delicate design nanoparticles required for simultaneous targeting, detection, therapeutic functions. Here the use Au/MnFe 2 O 4 (Au/MFO) Janus to target Gram‐positive via metabolic labeling reported realize integrated self‐reporting thermal bacteria. In these nanoparticles, Au component functionalized with tetrazine trans ‐cyclooctene group anchored on...
Earth observation imagery have traditionally been expensive, difficult to find and access, required specialized skills software transform into actionable information. This has limited adoption by the broader science community. Changes in cost of changes computing technology over last decade enabled a new approach for how organize, analyze, share imagery, broadly referred as data cube. The vision promise image cubes is lower these hurdles expand user community making analysis ready readily...
Most synthetic antimicrobial polymers are not biodegradable, thus limiting their potential for large-scale applications in personal care disinfection and environmental contaminations. Poly(ε-caprolactone) (PCL) is known to be both biodegradable biocompatible, representing an ideal candidate biopolymer applications. Here we successfully grafted alkylimidazolium (Im) onto PCL mimic the cationic properties of peptides. The poly(ε-caprolactone)-graft-butylimidazolium had only moderate MICs (32...
Significance We designed and synthesized antimicrobial compounds effective in killing pan-drug-resistant bacterial pathogens. These have a large therapeutic window due to their low mammalian cell toxicity. A lead compound showed efficacy treating murine model S. aureus P. aeruginosa infections. In the case of obligate respiratory bacterium we were unable evolve strains resistant these compounds. This paper points toward potential this type deal with current threat pan-resistant
Infections caused by nontuberculous mycobacteria have increased more than 50% in the past two decades and doubled elderly population.
Fish skin color is usually strongly affected by the background of their environment. The study investigated effects five different colors on leopard coral groupers (Plectropomus leopardus). More than 450 juveniles were reared in Blue, Red, Black, White, and Transparent tanks for 56 days. paraffin section showed that melanin zone fish White group was smaller, whereas Black Red groups (especially Black) nearly largest. apparent P. leopardus red white background, which darkened response to...
Modern portable electronic devices create a strong demand for flexible energy storage devices. Paper based nanocomposites are attractive as sustainable materials such applications. Here, we directly explored the hydroxyl chemistry of cellulose fibers to synthesize hybrid ternary nanocomposites, comprised rice paper, single-walled carbon nanotubes (SWCNTs) and manganese oxide nanoparticles. The functional groups on can react with adsorbed permanganate ions, resulting in uniform deposition...
Fish skin color is often strongly affected by background color. We hypothesized that the regulatory mechanism of variations in P. leopardus linked to In this study, we conducted transcriptome analysis Plectropomus cultured under different colors compare gene expression levels and important signaling pathways. The RNA-seq yielded 26,675 known mRNAs, 3278 novel 3179 differentially expressed genes (DEGs). DEGs related melanin synthesis were screened out. Some key melanin-related identified,...
There are common significant character differences between genders in many fish. The sex-specific genetic markers important tools for research and industry. Golden pompano (Trachinotus blochii) is a commercial mass-produced species with sex growth differences. Our study includes the whole genome re-sequencing data of T. blochii from four populations. A total 2,183,486 high-quality clean reads were obtained subsequent information analysis. Association analysis single nucleotide polymorphism...
The bicontinuous microemulsions consisting of methyl methacrylate (MMA), 2-hydroxyethyl (HEMA), water, and acryloyloxyundecyldimethylammonio acetate (AUDMAA) were polymerized using 2,2-dimethoxy-2-phenylacetophenone as a photoinitiator. They characterized by 1H NMR self-diffusion conductivity measurements before after polymerization. It is believed that microporous structures existed in these resulting transparent polymeric materials. Some microstructures may closely resemble those prior to...
Facility location problem (FLP) and vehicle routing (VRP) are two of the most challenging issues in logistics. This paper presents an exploration multinode facility location-routing with realistic conditions. The disposal centers, transfer stations, connected collection sites, unconnected sites built into a new hierarchical model which is solved by Generate Algorithm (GA). Model costs include node construction cost, pipeline transport cost. considers that transportation bidirectional flow...
Foxtail millet (Setaria italica) is an important cereal crop with rich nutritional value. Distinctness, Uniformity, and Stability (DUS) are the prerequisites for application of new variety rights foxtail millet. In this study, we investigated 32 DUS test characteristics 183 resources, studied their artificial selection trends, identified varieties that conform to breeding trends. The results indicated significant differences in terms means, ranges, coefficients variation each characteristic....