A5051995556- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Long-Term Effects of COVID-19
- Cardiovascular Syncope and Autonomic Disorders
- Intensive Care Unit Cognitive Disorders
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Glioma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neutropenia and Cancer Infections
- Pharmaceutical studies and practices
- Bacterial Identification and Susceptibility Testing
- Pharmacological Effects and Assays
- Disaster Response and Management
- Infectious Encephalopathies and Encephalitis
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Ion channel regulation and function
- Neuroinflammation and Neurodegeneration Mechanisms
- Emergency and Acute Care Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
University Hospitals of Leicester NHS Trust
2022-2024
NIHR Leicester Biomedical Research Centre
2023-2024
Glenfield Hospital
2023-2024
University of Leicester
2023
Orthostatic intolerance (OI), including postural orthostatic tachycardia syndrome (PoTS) and hypotension (OH), are often reported in long covid, but published studies small with inconsistent results. We sought to estimate the prevalence of objective OI patients attending covid clinics healthy volunteers associations symptoms comorbidities. Participants a diagnosis were recruited from eight UK clinics, general population. All undertook standardized National Aeronautics Space Administration...
Background: Long COVID (LC) is a multisystem clinical syndrome with functional disability and compromised overall health. Information on LC severity types emerging in cross-sectional studies. This study explored the pattern consistency of long over time prospective sample. Methods: Participants completed condition-specific outcome measure C19-YRSm (Yorkshire Rehabilitation Scale modified version) at two assessment points. A cluster analysis for was undertaken both points using k-means...
The protracted form of COVID-19 known as 'long covid' was first described in 2020. Its symptoms, course and prognosis vary widely; some patients have a multi-system, disabling prolonged illness. In 2021, ring-fenced funding provided to establish 90 long covid clinics England; were also established Scotland Wales. NIHR-funded LOCOMOTION project implemented UK-wide quality improvement collaborative involving ten these clinics, which ran from 2021 2023. At regular online meetings held...
Abstract Purpose Orthostatic intolerance (OI), including postural orthostatic tachycardia syndrome (PoTS) and hypotension (OH), are often reported in long covid, but published studies small with inconsistent results. We sought to estimate the prevalence of objective OI patients attending covid clinics healthy volunteers associations symptoms comorbidities. Methods Participants were recruited from 8 UK clinics, general population. All undertook standardised National Aeronautics Space...
Acute dyspnea is one of the most common presentations in acute/emergency settings, and acute pulmonary edema remains a leading cause adults resulting from either cardiogenic or non-cardiogenic etiologies. Neurogenic (NPE) less forms seen emergency departments, neurology units, intensive care units. It usually develops rapidly following significant neurological insult patients with intracranial hemorrhage, traumatic brain injuries, epileptic seizures. commonly after multitude other sudden...
<b>Background:</b> 65% of people with severe asthma and FeNO ≥45 ppb are non-adherent to inhaled corticosteroids (ICS). Digital monitoring that records both time-of-use inhaler technique can identify non-adherence ICS responsiveness but these devices not readily available. As the dose counter on NEXThaler™ only counts down when an inspiratory flow 35 L/min is achieved, this may present alternative identifying responsiveness. <b>Aim:</b> To use BDP/formoterol (200/6 mcg, 2 bd)...
Background: Long Covid (LC) is a multisystem clinical syndrome with Functional Disability (FD) and compromised Overall Health (OH). There lack of distinct symptom clusters (phenotypes) identified in LC so far but there emerging information on severity types. This study explores the consistency these types over time relationship between Symptom Severity (SS), FD, OH context prospective sample.Methods: A purposive sample patients recruited to LOng COvid Multidisciplinary consortium Optimising...