Yuan Gao

ORCID: 0009-0003-1403-843X
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About
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Research Areas
  • Ginseng Biological Effects and Applications
  • Genomics and Chromatin Dynamics
  • Genomics and Phylogenetic Studies
  • Epigenetics and DNA Methylation
  • Plant responses to water stress
  • Plant-Microbe Interactions and Immunity
  • Sperm and Testicular Function
  • Plant Disease Resistance and Genetics
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Plant tissue culture and regeneration
  • Genetic diversity and population structure
  • DNA Repair Mechanisms
  • Plant and animal studies

Shandong University
2025

University of Hong Kong
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2016

Abstract Background: The pangolin is a Pholidota mammal with large keratin scales protecting its skin. Two species (Manis pentadactyla and Manis javanica) have been recorded as critically endangered on the International Union for Conservation of Nature Red List Threatened Species. Optical mapping constructs high-resolution restriction maps from single DNA molecules genome analysis at megabase scale to assist assembly. Here, we constructed M. javanica using optical assembly these species....

10.1093/gigascience/giw001 article EN cc-by GigaScience 2016-12-01

As a valuable medicinal plant, the yield of Panax ginseng is seriously affected by autotoxicity, which common phenomenon due to continuous cropping. However, mechanism autotoxicity in P. still unknown. In total, high throughput sequencing 18 RNA-Seq libraries produced 996,000 000 100-nt reads that were assembled into 72,732 contigs. Compared with control, 3697 and 2828 genes significantly up- down-regulated across different tissues time points, respectively. Gene Ontology enrichment analysis...

10.1186/s12864-015-2151-7 article EN cc-by BMC Genomics 2015-11-25

Panax ginseng C. A. Meyer is a highly valued medicinal plant. Cylindrocarpon destructans destructive pathogen that causes root rot and significantly reduces the quality yield of P. ginseng. However, an efficient method to control remains unavailable because insufficient understanding molecular mechanism underlying destructans-P. interaction. In this study, destructans-induced transcriptomes at different time points were investigated using RNA sequencing (RNA-Seq). De novo assembly produced...

10.1371/journal.pone.0149408 article EN cc-by PLoS ONE 2016-02-18
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