A5053340612- Acute Ischemic Stroke Management
- Blood Coagulation and Thrombosis Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Viral Infections and Immunology Research
- Neurological Disorders and Treatments
- Viral gastroenteritis research and epidemiology
- RNA Research and Splicing
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- RNA and protein synthesis mechanisms
- Cytomegalovirus and herpesvirus research
Sydney Children's Hospital
2022-2023
Royal Adelaide Hospital
2023
Women's and Children's Hospital
2023
The incidence and natural history of large vessel occlusion (LVO) stroke in children is largely unknown. These knowledge gaps limit the uptake reperfusion therapies reduce efficiency pediatric acute pathways.To determine LVO stroke.This retrospective population-based cohort study was conducted between January 2010 December 2019, with a mean (SD) follow-up 37.0 (28.8) months. Admissions from all hospitals state New South Wales, Australia, final diagnosis arterial ischemic (AIS) patients 1...
Pediatric large vessel occlusion (LVO) stroke has a poor natural history. However, uptake of mechanical thrombectomy is hindered by lack clinical trial data in children. A randomized not feasible due to small sample sizes and absence equipoise.
To improve delivery of acute therapies for ischaemic stroke (AIS).We identified factors influencing the speed diagnosis and in a prospective cohort 21 children with suspected AIS (eight AIS, 13 mimics) explored them retrospective confirmed AIS.Approximately half total cohorts presented acute, sustained hemiparesis, were diagnosed relatively quickly. was more slowly presenting symptoms other than hemiparesis. Thirty-one out 51 patients (19 females, 32 males, mean age 8 years 6 months, SD 5 4...
ABSTRACT Background Thrombolysis is infrequently delivered to children with acute ischemic stroke (AIS). Consideration of eligibility criteria and outcomes after AIS may enhance utility thrombolysis in pediatric AIS. Methods This retrospective observational study assessed for tissue plasminogen activator (tPA) outcome a 10-year population cohort 151 first symptomatic 68 children. Outcomes among small vessel AIS, residual brain tumors intracranial dissection, who are currently excluded from...
Background: Paediatric large vessel occlusion (LVO) stroke has a poor natural history. However, uptake of mechanical thrombectomy is hindered by lack clinical trial data in children. A randomized not feasible due to small sample sizes and absence equipoise. matched case-control study allows for comparative this scenario. We hypothesized that paediatric patients with acute LVO who undergo have better outcomes than managed conservatively.Methods: undertook multi-centre retrospective across...