Prakash Muthusami

ORCID: 0000-0002-7062-9571
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About
Contact & Profiles
Research Areas
  • Vascular Malformations Diagnosis and Treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Acute Ischemic Stroke Management
  • Moyamoya disease diagnosis and treatment
  • Advanced MRI Techniques and Applications
  • Blood Coagulation and Thrombosis Mechanisms
  • Cerebral Venous Sinus Thrombosis
  • Central Venous Catheters and Hemodialysis
  • Cerebrovascular and Carotid Artery Diseases
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Venous Thromboembolism Diagnosis and Management
  • Vascular Procedures and Complications
  • Advanced Neuroimaging Techniques and Applications
  • Renal and Vascular Pathologies
  • Ocular Oncology and Treatments
  • Congenital Heart Disease Studies
  • Vascular anomalies and interventions
  • Neurological Complications and Syndromes
  • MRI in cancer diagnosis
  • Vascular Malformations and Hemangiomas
  • Radiation Dose and Imaging
  • Peripheral Artery Disease Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Aortic Disease and Treatment Approaches
  • Pediatric Urology and Nephrology Studies

Hospital for Sick Children
2016-2025

SickKids Foundation
2015-2025

University of Toronto
2016-2025

Guided Therapeutics (United States)
2023

Systems, Applications & Products in Data Processing (Canada)
2021

Lucile Packard Children's Hospital
2018

Toronto Western Hospital
2018

St. Michael's Hospital
2016

University College London
2015

Great Ormond Street Hospital
2015

The incidence and natural history of large vessel occlusion (LVO) stroke in children is largely unknown. These knowledge gaps limit the uptake reperfusion therapies reduce efficiency pediatric acute pathways.To determine LVO stroke.This retrospective population-based cohort study was conducted between January 2010 December 2019, with a mean (SD) follow-up 37.0 (28.8) months. Admissions from all hospitals state New South Wales, Australia, final diagnosis arterial ischemic (AIS) patients 1...

10.1001/jamaneurol.2022.0323 article EN JAMA Neurology 2022-03-28

Pediatric large vessel occlusion (LVO) stroke has a poor natural history. However, uptake of mechanical thrombectomy is hindered by lack clinical trial data in children. A randomized not feasible due to small sample sizes and absence equipoise.

10.1001/jamaneurol.2023.2303 article EN JAMA Neurology 2023-07-24

Arteriopathy is common in childhood arterial ischemic stroke (AIS) and predicts recurrence. Currently available vascular imaging techniques mainly image the lumen rather than vessel wall have a limited ability to differentiate among arteriopathies. We aimed investigate value of magnetic resonance imaging-based technique, namely noninvasive (AWI), for distinguishing arteriopathy subtypes consecutive cohort children presenting with AIS.Children confirmed AIS angiography underwent 3-Tesla AWI...

10.1161/strokeaha.117.019827 article EN Stroke 2018-03-16

<h3>Importance</h3> Major neurological complications from the embolization of vein Galen malformations (VOGMs) are poorly understood. We provide a detailed analysis contributors to periprocedural and lessons learned. <h3>Objective</h3> To assess rate major following VOGM with procedural strategic contributors. <h3>Design, Setting, Participants</h3> This retrospective cohort study was conducted at quarternary referral pediatric hospital (Hospital for Sick Children; Toronto, Ontario, Canada)...

10.1001/jamaneurol.2020.0825 article EN JAMA Neurology 2020-04-27

Abstract CNS vascular syndromes are being increasingly recognized and diagnosed in the pediatric population. Their rarity complexity makes diagnosis challenging. These can present a number of different ways clinically radiologically. A systematic method image interpretation often reveals pattern, allowing to be narrowed or further testing directed. Although appearance itself is rarely specific, additional information gleaned from imaging other systems aids pattern recognition. We...

10.1093/bjr/tqaf057 article EN cc-by-nc British Journal of Radiology 2025-03-13

SummaryBackgroundEmerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes versus in children intracranial arterial occlusion stroke.MethodsIn this prospective registry study, 45 centres 12 countries across Asia Australia, Europe, North America, South America reported aged between 28 days 18 years presenting...

10.1016/s2352-4642(24)00233-5 article EN cc-by The Lancet Child & Adolescent Health 2024-10-11

<h3>BACKGROUND AND PURPOSE:</h3> MRI is routinely performed following brain AVM after treatment in children. Our aim was to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for recurrence children, compared with conventional angiography role 3D rotational angiography–MR fusion these cases. <h3>MATERIALS METHODS:</h3> We included all pediatric patients AVMs during an 18-year period angiographically documented obliteration treatment. Patients underwent 3T imaging,...

10.3174/ajnr.a6093 article EN cc-by American Journal of Neuroradiology 2019-06-27

Purpose To estimate reference ranges for blood flow volume (BFV) in major splanchnic, thoracoabdominal, and neck vessels by using phase-contrast magnetic resonance (MR) imaging children young adults fasting postprandial states. Materials Methods In this institutional research ethics board–approved prospective study, healthy volunteers underwent MR a state again after standardized meal. BFV values were reported as medians ranges, postmeal to premeal ratios calculated. BFVs divided into two...

10.1148/radiol.2017162114 article EN Radiology 2017-05-22

Unilateral pulmonary artery agenesis is commonly seen associated with other congenital cardiovascular defects, when it detected early in life, but isolated absence of the a rare entity, usually adulthood. The latter patients are asymptomatic or might present varied non-specific manifestations such as respiratory tract infections and hemoptysis. This report describes imaging findings 67 year old female right artery. embryology clinical condition reviewed.

10.3941/jrcr.v4i11.583 article EN cc-by-nc-nd Journal of Radiology Case Reports 2010-11-14
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