Guo Yong

ORCID: 0009-0003-3975-0474
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About
Contact & Profiles
Research Areas
  • Biofuel production and bioconversion
  • Reproductive Biology and Fertility
  • Genomics and Chromatin Dynamics
  • Enzyme Production and Characterization
  • Plant Molecular Biology Research
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering
  • Innovations in Medical Education
  • Plant tissue culture and regeneration
  • Plant Reproductive Biology
  • Genomics and Phylogenetic Studies
  • Fermentation and Sensory Analysis
  • Transgenic Plants and Applications
  • Genetic and phenotypic traits in livestock
  • 3D Printing in Biomedical Research
  • Seed Germination and Physiology
  • Medical Research and Treatments
  • Microbial Metabolic Engineering and Bioproduction
  • Reproductive Physiology in Livestock
  • Sperm and Testicular Function
  • Science, Research, and Medicine
  • Reproductive tract infections research
  • Microbial Community Ecology and Physiology
  • Biotechnology and Related Fields
  • Magnetic and Electromagnetic Effects

Max Delbrück Center
2020-2023

South China Normal University
2010-2011

First Affiliated Hospital of Sichuan Medical University
2010

Southwest Medical University
2010

Southerners on New Ground
2001-2002

South China Agricultural University
2000

Transposons are parasitic genetic elements that frequently hijack vital cellular processes of their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously identified as host-encoded factor Sleeping Beauty (SB) transposition. Here, we show predominantly maternally expressed, and marks both germinal progenitor somatic stem cells. SB piggybacks to activate transposase expression target transposition cells, thereby potentiating heritable transposon insertions. The promoter...

10.3390/ijms24087283 article EN International Journal of Molecular Sciences 2023-04-14

Abstract Transposons are parasitic genetic elements that frequently hijack key cellular processes of the host. HMGXB4 is a Wnt signalling-associated HMG-box protein, previously identified as transcriptional regulating host factor Sleeping Beauty (SB) transposition. Here, we establish highly expressed from zygote stage, and declines after genome activation. Nevertheless, activated by its own promoter at 4-cell responding to parental-to-zygotic transition, marks stemness, maintains expression...

10.1101/2020.06.15.145656 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-06-15
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