A5028639507- Developmental Biology and Gene Regulation
- Genetic Mapping and Diversity in Plants and Animals
- Neuroendocrine regulation and behavior
- Animal Vocal Communication and Behavior
- Genetic diversity and population structure
- RNA Research and Splicing
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic and phenotypic traits in livestock
- Animal Behavior and Reproduction
- Animal Genetics and Reproduction
- Single-cell and spatial transcriptomics
- Genomics and Chromatin Dynamics
- Neuroinflammation and Neurodegeneration Mechanisms
- Congenital heart defects research
- Immune cells in cancer
- Nutrition, Genetics, and Disease
- dental development and anomalies
- Hedgehog Signaling Pathway Studies
- Genetics, Aging, and Longevity in Model Organisms
- Infant Health and Development
Max Planck Institute for Evolutionary Biology
2014-2025
Max Planck Institute of Biochemistry
2024
Max Planck Institute for Biological Intelligence
2024
Baylor College of Medicine
1992-1993
Howard Hughes Medical Institute
1992-1993
Ludwig-Maximilians-Universität München
1989-1990
Max Planck Society
1989
The apterous (ap) gene is required for the normal development of wing and haltere imaginal discs in Drosophila melanogaster. ap encodes a new member LIM family developmental regulatory genes. deduced amino acid sequence predicts homeo domain cysteine/histidine-rich known as domain. In these domains highly similar to mec-3 lin-11 proteins Caenorhabditis elegans vertebrate insulin enhancer-binding protein isl-1. presumably transcriptional regulation genes involved development. nature defects...
It has long been known that rodents emit signals in the ultrasonic range, but their role social communication and mating is still under active exploration. While inbred strains of house mice have emerged as a favourite model to study vocalisation (USV) patterns, studies wild animals natural situations are rare. We focus here on two derived mouse populations. recorded them dyadic encounters for extended periods time assess possible roles USVs divergence between allopatric analysed song...
House mice (Mus musculus) live in social groups where they frequently interact with conspecifics, thus communication (e.g. chemical and/or auditory) is essential. It commonly known that male and female produce complex vocalizations the ultrasonic range (USV) remind of high-pitched birdsong (so called mouse song) which mainly used interactions. Earlier studies suggest use their USVs for mate attraction choice, but could also be as signal during hierarchy establishment familiarization, or...
Abstract De novo evolved genes emerge from random non-coding sequences and have, therefore, no homologs which a function could be inferred. While expression analysis knockout experiments can provide insights into the function, they do not directly test whether gene is beneficial for its carrier. Here, we have used seminatural environment experiment to fitness of previously identified de mouse Pldi , thought involved in sperm differentiation. We strain this competed it against parental...
De novo evolved genes emerge from random parts of noncoding sequences and have, therefore, no homologs which a function could be inferred. While expression analysis knockout experiments can provide insights into the function, they do not directly test whether gene is beneficial for its carrier. Here, we have used seminatural environment experiment to fitness previously identified de mouse Pldi, has been implicated role in sperm differentiation. We strain this competed it against parental...
The transcription factor FoxP2 is involved in setting up the neuronal circuitry for vocal learning mammals and birds thought to have played a special role evolution of human speech language. It has been shown that an allele with humanized version murine Foxp2 gene changes ultrasonic vocalization mouse pups compared wild-type inbred strain. Here we tested if this would also affect adult female male mice. In previous study, which only was considered mice were recorded under restricted spatial...