A5104157993- Inflammatory Bowel Disease
- Biosimilars and Bioanalytical Methods
- Microscopic Colitis
- Pharmaceutical studies and practices
- Gastrointestinal disorders and treatments
- Drug-Induced Adverse Reactions
- Chronic Lymphocytic Leukemia Research
- Pancreatitis Pathology and Treatment
- Acute Lymphoblastic Leukemia research
- Systemic Lupus Erythematosus Research
- Abdominal Surgery and Complications
- Palliative Care and End-of-Life Issues
- Muscle and Compartmental Disorders
- Celiac Disease Research and Management
- Abdominal vascular conditions and treatments
- Patient-Provider Communication in Healthcare
- Autoimmune and Inflammatory Disorders
- Amoebic Infections and Treatments
- Pharmacological Effects and Toxicity Studies
- Ethics in medical practice
- Empathy and Medical Education
- Gallbladder and Bile Duct Disorders
- Lipoproteins and Cardiovascular Health
- Diagnosis and treatment of tuberculosis
- Kawasaki Disease and Coronary Complications
Instituto Murciano de Investigación Biosanitaria
2023-2024
Hospital Reina Sofía de Murcia
2009-2024
Hospital Universitario Reina Sofía
2020-2024
Hospital General Universitario Santa María del Rosell
2006-2007
Hospital Universitario Virgen de la Arrixaca
2002-2005
Introduction numerous studies have shown a positive correlation between serum biologic drug concentrations and favorable therapeutic outcomes during the induction maintenance period in patients with Crohn's disease (CD). To our knowledge, only few contradictory determined association ustekinumab (UST) trough biological outcomes. This study aimed to investigate relationship real-world setting. Methods cross-sectional cohort was performed. All adult CD who received therapy (≥ 24 weeks) were...
infliximab is used in inflammatory bowel disease, which has a great inter-individual pharmacokinetic variability. Thus, it necessary to individualize the therapy many cases. The main objective of our study was compare two methods dose adjustment strategy using therapeutic drug monitoring: a) based on an algorithm and b) Bayesian prediction, achieve optimal trough level patients with diseases. secondary evaluate predictive performance population model diseases therefore, its clinical utility....
Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location therapeutic patterns.
efficacy and safety were evaluated after switching to a biosimilar infliximab (CPT-13) in patients with inflammatory bowel disease (IBD). However, few cohort studies compare the pharmacokinetic profiles, immunogenicity, of reference (IFX) CPT-13 real clinical setting.to profiles drug survival on long term IFX at weeks 54 104. A secondary objective was determine long-term immunogenicity profile IBD setting.a retrospective, observational analysis performed single center, including under...
previous studies have shown that higher infliximab trough levels are associated with favorable short-term and long-term therapeutic outcomes in inflammatory bowel disease. There is a need to determine which patients could benefit from proactive drug monitoring the induction phase. The aim of this study was evaluate pharmacokinetic variability infliximab, factors achieving target phase analyze clinical biochemical response at week 26 treatment.a retrospective observational performed disease...
Amebic colitis is a low prevalence illness in developed countries. Its diagnosis infrequent and usually made certain groups of risk. Images studies are not useful differential with other illnesses as Inflammatory Bowel Disease (IBS). Next clinical note shows the problems amebic an immunocompetent host without risk factors.
The aim of this study was to determine the prevalence immunogenicity in patients receiving anti-TNF drugs (infliximab and adalimumab) our hospital analyse if there are differences terms between these drugs. We conducted a retrospective observational May 2015 October 2018, reference area (330 beds). included all diagnosed with inflammatory bowel disease that received treatment infliximab or adalimumab serum levels 2018. variables studied were: sex, age, number samples collected, main...
informed consent is necessary for invasive procedures as a document that guarantees the ethical health relationship and patient safety.to analyze whether we have use documents paracentesis in our hospitals to obtain data on technique.a descriptive observational study was performed during December 2019, via cross-sectional survey disseminated through social networks, aimed at specialists residents of gastroenterology.two hundred three anonymous surveys were included (55.2 % gastroenterologist...