A5092355981- Plant Gene Expression Analysis
- Cancer-related molecular mechanisms research
- Horticultural and Viticultural Research
- Fermentation and Sensory Analysis
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
First Affiliated Hospital of Zhengzhou University
2024
Shandong Agricultural University
2023
Pear fruit stone cells have thick walls and are formed by the secondary deposition of lignin in primary cell wall thin-walled cells. Their content size seriously affect characteristics related to edibility. To reveal regulatory mechanism underlying formation during pear development identify hub genes, we examined contents 30 'Shannongsu' flesh samples analyzed transcriptomes 15 collected at five developmental stages. On basis RNA-seq data, 35 874 differentially expressed genes were detected....
Osteoarthritis (OA) is a prevalent degenerative joint disease with lack of effective therapeutic. Chondrocyte ferroptosis contributes to the progression OA. PUM2 shown exacerbate ischemia-reperfusion-induced neuroinflammation by promoting ferroptosis, but its role in OA remains unexplored. Here, primary mouse chondrocytes were stimulated IL-1β mimic chondrocyte injury vitro. And was upregulated cartilage tissues and IL-1β-induced chondrocytes. Silencing alleviated inflammation ECM...