- Diatoms and Algae Research
- Algal biology and biofuel production
- Microbial Community Ecology and Physiology
- Photosynthetic Processes and Mechanisms
- Microbial Natural Products and Biosynthesis
- Biocrusts and Microbial Ecology
Scripps Institution of Oceanography
2024-2025
University of California, San Diego
2024-2025
Metals are important cofactors in the metabolic processes of cyanobacteria, including photosynthesis, cellular respiration, DNA replication, and biosynthesis primary secondary metabolites. In adaptation to marine environment, cyanobacteria use metallophores acquire trace metals when necessary as well reduce potential toxicity from excessive metal concentrations. Leptochelins A–C were identified structurally novel three geographically dispersed genus Leptothoe. Determination complex...
A structurally novel metabolite, fatuamide (1), was discovered from a laboratory cultured strain of the marine cyanobacterium Leptolyngbya sp., collected Faga'itua Bay, American Samoa. bioassay-guided approach using NCI-H460 human lung cancer cells directed isolation A, which obtained most cytotoxic fraction. The planar structure elucidated by integrated NMR and MS/MS analysis, combination bioinformatic computational approaches used to deduce absolute configuration at its eight...
Metals are important co-factors in the metabolic processes of cyanobacteria including photosynthesis, cellular respiration, DNA replication, and biosynthesis primary secondary metabolites. In adaptation to marine environment, use metallophores acquire trace metals when necessary as well reduce potential toxicity from excessive metal concentrations. Leptochelins A-C were identified structurally novel three geographically dispersed genus Leptothoe. The leptochelins halogenated linear NRPS-PKS...