A5103104593- Cancer-related cognitive impairment studies
- Epigenetics and DNA Methylation
- Cancer survivorship and care
- Histone Deacetylase Inhibitors Research
- DNA Repair Mechanisms
- Cancer-related Molecular Pathways
- Family Support in Illness
- Glioma Diagnosis and Treatment
- Microbial Natural Products and Biosynthesis
- Research on Leishmaniasis Studies
- Marine Biology and Environmental Chemistry
- Ear and Head Tumors
- Signaling Pathways in Disease
- Head and Neck Surgical Oncology
- Chronic Myeloid Leukemia Treatments
- Protein Kinase Regulation and GTPase Signaling
- Marine Sponges and Natural Products
- Global Cancer Incidence and Screening
- Fungal Plant Pathogen Control
- Head and Neck Cancer Studies
Renji Hospital
2024
Shanghai Jiao Tong University
2024
Ocean University of China
2021-2022
Qingdao National Laboratory for Marine Science and Technology
2021
Guangzhou University of Chinese Medicine
2019
Beijing Normal University
2009
Marine natural products play critical roles in the chemical defense of many marine organisms and are essential, reputable sources successful drug leads. Sixty-seven 14-membered resorcylic acid lactone derivatives 3-27 30-71 product zeaenol (1) isolated from marine-derived fungus Cochliobolus lunatus were semisynthesized by chlorination, acylation, esterification, acetalization one to three steps. The structures these new established HRESIMS NMR techniques. All compounds (1-71) evaluated for...
Background Young women often face substantial psychological challenges in the initial years following cancer diagnosis, leading to a comparatively lower quality of life than older survivors. While mobile apps have emerged as potential interventions, their effectiveness remains inconclusive due diversity intervention types and variation follow-up periods. Furthermore, there is particular dearth evidence regarding efficacy these apps’ intelligent features addressing distress with apps....
Brefeldin A (1), a potent cytotoxic natural macrolactone, was produced by the marine fungus Penicillium sp. (HS-N-29) from medicinal mangrove Acanthus ilicifolius. Series of its ester derivatives 2–16 were designed and semi-synthesized, their structures characterized spectroscopic methods. Their activities evaluated against human chronic myelogenous leukemia K562 cell line in vitro, preliminary structure–activity relationships revealed that hydroxy group played an important role. Moreover,...
Abstract Rationale: Due to the anatomical and biological characteristics of nasopharyngeal carcinoma (NPC), radiotherapy is standard treatment choice. Recent advances in small molecule therapies targeting tumor angiogenesis also hold promise for advanced NPC. Patient concerns: The patient's symptoms, including nasal obstruction, bleeding, headache, reappeared periodically eventually became so severe that vision impaired. In January 2016, patient presented with blurred vision, diplopia,...
<sec> <title>BACKGROUND</title> Young women often face substantial psychological challenges in the initial years following cancer diagnosis, leading to a comparatively lower quality of life than older survivors. While mobile apps have emerged as potential interventions, their effectiveness remains inconclusive due diversity intervention types and variation follow-up periods. Furthermore, there is particular dearth evidence regarding efficacy these apps’ intelligent features addressing...