A5024756301- Cancer therapeutics and mechanisms
- Mesenchymal stem cell research
- Breast Lesions and Carcinomas
- Diabetes and associated disorders
- Diet and metabolism studies
- Diabetes Treatment and Management
- Biomarkers in Disease Mechanisms
- Bone health and osteoporosis research
- Wound Healing and Treatments
- Diet, Metabolism, and Disease
- AI in cancer detection
- Cancer Mechanisms and Therapy
- COVID-19 Clinical Research Studies
- Pancreatic function and diabetes
- SARS-CoV-2 and COVID-19 Research
- Cannabis and Cannabinoid Research
- Quinazolinone synthesis and applications
- Computational Drug Discovery Methods
- Breast Cancer Treatment Studies
- Intramuscular injections and effects
- Hip and Femur Fractures
- Synthesis and biological activity
Sapienza University of Rome
2024-2025
Ziauddin University
2021-2024
Royal Derby Hospital
2024
Dow University of Health Sciences
2024
Burton Hospitals NHS Foundation Trust
2024
Liaquat National Hospital
2024
Karachi Medical and Dental College
2022
Obesity remains a major epidemic in developed countries, with limited range of effective pharmacological treatments. The modulation PPARα, CB1, or GLP-1 receptor activity has demonstrated beneficial effects, including anti-obesity actions. In this study, we evaluated novel amide derivative oleic acid and tyrosol (Oleyl hydroxytyrosol ether, OLHHA), PPARα agonist, CB1 antagonist, combination the agonist liraglutide (LIG), as an multitarget therapy to improve both peripheral central...
Background Coronavirus disease 2019 (COVID-19) is a major public health problem worldwide, and vaccination currently the most effective way to control its spread reduce severity. Diabetes mellitus (DM) prevalent chronic that poses significant risk frequent comorbidity in COVID-19 patients. Therefore, this study aimed assess frequency of local systemic side effects AstraZeneca vaccine among diabetic non-diabetic participants. Methodology This multicenter was designed as cross-sectional...
Continuous obstacles behind the discovery of novel drugs for cancer therapy have necessitated development alternative strategy drug repurposing—the old new therapeutic purposes. With an improved understanding hallmarks cancer, this offers a cost-effective process treatment human neoplastic disease, thereby facilitating rapid clinical translation. In regard, macrolide antibiotics (MAs), which include wide spectrum activities against Gram-positive bacteria, also been proposed as anticancer...
Aims: To assess the association of BMD (bone mineral density) with ethnicity and parity in females Karachi, Pakistan. Study design: Cross Sectional. Place duration study: Department Anatomy & Nuclear Medicine, Ziauddin Hospital, Clifton Campus, Pakistan between March August 2016. Methods: 200 aged 40 years above were included. Average age was 60.7 (±10.52). assessment done on DXA scans. Participants interviewed to obtain baseline demographic characteristics. Statistical Package for...
Illegal trade, White-breasted water hen, Mardan, TownsMany of the waterbird species are generally thought to be threatened mainly or at least partly by over hunting.This paper provides novel information on causal factors that lead hunting and illegal trade waterhen Amaurornis phoenicurus in a remote villages district Khyber Pakhtunkhwa, Pakistan.Data were collected adopting mix scientific approach including Participants' observations, interviews structured questionnaire.Our results showed...
NR collected and analyzed the data, experiments wrote article BW, SU KH planed study.KH helped in experiments.SU data.MS reviewing article.MS DZ arranged data.ST sample collection.TU
Background: Fibroadenoma (FA) is one of the most frequently diagnosed benign neoplasm in women. Various researches have reported increased risk breast cancer females with FA. It stems from proliferation epithelial and stromal contents terminal duct lobular units (TDLU`S) tissue, that are primary sites for histopathologic assessment which gold standard diagnosis disease. However, this method subjective possess interobserver variability. Therefore, new quantitative methods required to aid...
Over the past few years great progress has been achieved in anticancer therapy, but development of resistance and unavoidable side effects have incapacitated these fulfilments. Keeping view this demanding condition, numerous drugs with unique antitumor mechanisms are under investigations including antimicrobials which shown to possess anti-inflammatory, immunomodulatory cytotoxic effects. In regard, both conventional novel being studied explore their potential along underlying may render...