A5112973807- Paleontology and Stratigraphy of Fossils
- Tissue Engineering and Regenerative Medicine
- Geological and Geochemical Analysis
- Geology and Paleoclimatology Research
- Nerve injury and regeneration
- Geological and Geophysical Studies
- Electrospun Nanofibers in Biomedical Applications
- Geochemistry and Geologic Mapping
- earthquake and tectonic studies
- Methane Hydrates and Related Phenomena
- Renal and related cancers
- Genomics and Phylogenetic Studies
- Protist diversity and phylogeny
- 3D Printing in Biomedical Research
- Microbial Community Ecology and Physiology
- Geological Studies and Exploration
- Geological formations and processes
- Hydrocarbon exploration and reservoir analysis
- Global Security and Public Health
- Geochemistry and Elemental Analysis
- Nonlinear Photonic Systems
- Extracellular vesicles in disease
- Medical Image Segmentation Techniques
- Antimicrobial Peptides and Activities
- Insect Utilization and Effects
Nanjing Institute of Geology and Paleontology
2022-2024
Chinese Academy of Sciences
2022-2024
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2024
Guangzhou Institutes of Biomedicine and Health
2022-2024
Southwest University
2022-2023
Nanjing University
2018-2023
American College of Dubai
2023
South China Normal University
2018-2020
Sun Yat-sen University
2018-2020
Qingdao National Laboratory for Marine Science and Technology
2020
Synergistic intercellular interactions have been widely acknowledged in tuning functional cell behaviors vivo, and these inspired the development of a variety scaffolds for regenerative medicine. In this paper, promotion Schwann (SC)-neurite through use nerve extracellular matrix-coated nanofiber composite vitro was demonstrated using culturing platform consisting either random or aligned electrospun poly(l-lactic acid) nanofibers decellularized peripheral matrix gel (pDNM gel) from porcine...
The clinical therapeutics for nerve tissue regeneration and functional recovery after spinal cord injury (SCI) are very limited because of the complex biological processes inhibitory microenvironment. Advanced biomaterials highly desired to avoid severe secondary damage provide guidance axonal regrowth. Multichannel nanofibrous scaffolds were modified with gelatin cross-linked by genipin. gelatin-coated nanofibers exhibited strong binding affinity neurotrophin-3, which underwent a...
Abstract The timing of continental collision between Arabia and Eurasia is a highly controversial issue, on which new constraints are here provided from the Amiran Basin (Zagros Mountains, Iran). Upper Cretaceous carbonate ramps grown along Arabian northern margin overlain by siliciclastic deep-water shallow-water Kashkan Formations, dated biostratigraphically as 64–60 Ma (Paleocene) 56–52 (earliest Eocene), respectively. Abundant ophioliticlastics, detrital Cr-spinel geochemistry, zircons...
Nerve defects are challenging to address clinically without satisfactory treatments. As a reliable alternative autografts, decellularized nerve matrix scaffolds (DNM-S) have been widely used in clinics for surgical repair. However, DNM-S remain inferior autografts their ability support regeneration long defects. In this study, we systematically and clearly presented the nano-architecture of nerve-specific structures, including endoneurium, basement membrane perineurium/epineurium DNM-S....
Neurological functional recovery depends on the synergistic interaction between angiogenesis and neurogenesis after peripheral nerve injury (PNI). Decellularized matrix hydrogels have drawn much attention been considered as potential therapeutic biomaterials for neurovascularization, due to their intrinsic advantages in construction of a growth-permissive microenvironment, strong affinity multiple growth factors (GFs), promotion neurite outgrowth. In present study, factor (NGF) vascular...
Few stratigraphical and micropalaeontological data are available from Upper Cretaceous shallow-water marine carbonates of the southwestern Tarim Basin, western China. The present study provides new about microfauna calcareous algae Cenomanian-Turonian Kukebai Formation Campanian Yigeziya Formation. investigated bioclastic yield a rather poorly diversified (benthic foraminifers) contrasting with relatively well assemblage dasycladalean green comprising 16 taxa. For several taxa, material does...
ADA16 peptide hydrogels have been broadly used in tissue engineering due to their good biocompatibility and nanofibrous structure mimicking the native extracellular matrix (ECM). However, low mechanical strength often fails them as implantable scaffolds. To improve stability of RADA16 hydrogel, a photocrosslinkable diacrylated poly(ϵ-caprolactone)-b-poly(ethylene glycol)-b-poly(ϵ-caprolactone) triblock copolymer (PCECDA) was physically combined with pre-modified cell adhesive Arg-Gly-Asp...
Abstract Widespread accumulation of thick carbonates is not typical orogenic settings. During the mid-Cretaceous, near Bangong suture in northern Lhasa terrane, shallow-marine Langshan Formation, reaching a thickness up to ~1 km, accumulated an epicontinental seaway over modern area 132 × 103 km2, about half Arabian/Persian Gulf. The origin basin-wide carbonate deposits located close newly formed belt well understood, partly because scarcity paleogeographic studies on evolution Lhasa. Based...
Abstract Global sea-level changes strongly impact within-basin depositional patterns and the evolution of palaeoclimate, palaeogeography palaeoecology. During long, worldwide ice-free period in mid-Cretaceous greenhouse time interval, high-frequency global were recorded sedimentary archives. However, causes these are still debated. In central Tibet, 1 km-thick Langshan Formation has been dated to late Aptian early Cenomanian based on larger benthic foraminifera accumulated an epeiric seaway,...
The combination of levulinic acid (LVA) and sodium dodecyl sulfate (SDS) in recent years has shown a considerable potential to use as an antimicrobial intervention. objectives this study were evaluate the efficacy against Staphylococcus aureus both planktonic biofilm states investigate transcriptional changes S. biofilms coincubated with sublethal concentrations LVA and/or SDS. minimum inhibitory (MICs) SDS determined by microdilution method 3.125 0.039 mg/mL, respectively. An additive...
Astrocytes are the most abundant and widespread glial cells in central nervous system. The heterogeneity of astrocytes plays an essential role spinal cord injury (SCI) repair. Decellularised matrix (DSCM) is advantageous for repairing SCI, but little known regarding exact mechanisms niche alterations. Here, we investigated DSCM regulatory mechanism neuro-glial-vascular unit using single-cell RNA sequencing. Our single cell sequencing, molecular biochemical experiments validated that...
Eocene Thermal Maximum, PETM)、早 始新世极热事件2(Eocene Maximum 2, ETM2)、早始新世极热事件3(Eocene 3, ETM3)等