A5076556530- Monoclonal and Polyclonal Antibodies Research
- Prostate Cancer Treatment and Research
- Peptidase Inhibition and Analysis
- RNA and protein synthesis mechanisms
- Cancer-related gene regulation
- Viral Infectious Diseases and Gene Expression in Insects
- CAR-T cell therapy research
- Protein purification and stability
- Amino Acid Enzymes and Metabolism
- DNA and Nucleic Acid Chemistry
- Lymphoma Diagnosis and Treatment
- Phagocytosis and Immune Regulation
- Viral gastroenteritis research and epidemiology
- Galectins and Cancer Biology
- interferon and immune responses
- Advanced Biosensing Techniques and Applications
- Retinoids in leukemia and cellular processes
- Microfluidic and Bio-sensing Technologies
- Biotin and Related Studies
- Vitamin D Research Studies
- Signaling Pathways in Disease
- Steroid Chemistry and Biochemistry
- Advanced biosensing and bioanalysis techniques
- Hepatitis Viruses Studies and Epidemiology
- Acupuncture Treatment Research Studies
Pirogov Russian National Research Medical University
2017-2025
Moscow Polytechnic University
2025
Tomsk National Research Medical Center
2017-2024
Russian Academy of Sciences
2017-2024
BIOCAD (Russia)
2023
Ministry of Health of the Russian Federation
2020
Siberian State Medical University
2016
Tomsk Cancer Research Institute
2013-2015
National Research Tomsk State University
2015
Goethe University Frankfurt
2009-2012
Aim . To assess the concentrations of bacterial and eukaryotic metabolites mainly involved in indole, kynurenine, serotonin pathways tryptophan metabolism a cohort patients with obesity. Materials methods. Using high-performance liquid chromatography mass spectrometric detection, several serum metabolites, such as kynurenic acid, anthranilic xanthurenic quinolinic 5-hydroxyindole-3-acetate, tryptamine, serotonin, indole-3-lactate, indole-3-acetate, indole-3- butyrate,...
The engineering of bispecific antibodies that exhibit optimal affinity and functional activity presents a significant scientific challenge. To tackle this, investigators employ an assortment protein assay techniques, such as label-free interaction methodologies, which offer rapidity convenience for the evaluation extensive sample sets. These assays yield intricate data pertaining to towards target antigens Fc-receptors, instrumental in predicting cellular test outcomes. Nevertheless,...
Introduction. Rotavirus infection (RVI) is the most common cause of severe gastroenteritis in infants and young children worldwide: 600,000 die annually; it accounts for approximately 3 million hospitalizations 25 physician visits each year among children. Preventive vaccination universally recognized as effective measure against this infection.The purpose study assessment reactogenicity, safety immunogenicity pentavalent live vaccine RVI prevention childhood immunization.Materials methods....
Epstein–Barr virus (EBV) associated gastric carcinoma is a special form of adenocarcinoma that arises against the background clonal growth EBV-infected epithelial cells mucosa. This subtype tumors has unique genetic and epigenetic features determine its characteristic phenotype. Determination molecular EBV-associated cancer made it possible to identify potential targets for drug therapy this tumors. The review presents modern data on epidemiology pathogenesis EBVassociated cancer, describes...
Bispecific antibodies (bsAbs) belong to the group of promising biotherapeutics, as their structural and functional features provide versatility. To put it simply, bsAbs bind two antigens or epitopes on one antigen simultaneously, moreover, they are capable directing effector immune cells cancer delivering payloads (radionuclides, toxic agents, immunological payloads) target cells, thus offering a broad spectrum clinical applications. Current review is focused platform engineering...
Transmembrane prostate androgen-induced protein 1 (TMEPAI) is a membrane that has attracted significant attention of many researchers its involvement in TGF-β signaling pathway which involved malignant transformation and metastatic tumor progression. We investigated the TMEPAI expression level gastric adenocarcinomas comparison to non-tumor mucosa samples determined potential prognostic significance. Fresh paraffin-embedded adenocarcinoma paired adjacent normal tissues were collected from...