A5063863618- Multiple and Secondary Primary Cancers
- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Acute Lymphoblastic Leukemia research
- Childhood Cancer Survivors' Quality of Life
- Global Cancer Incidence and Screening
- Lung Cancer Treatments and Mutations
- Lymphoma Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Cancer Diagnosis and Treatment
- Insect and Pesticide Research
- Healthcare Technology and Patient Monitoring
- Chemotherapy-induced cardiotoxicity and mitigation
- Metastasis and carcinoma case studies
- HER2/EGFR in Cancer Research
- Hospital Admissions and Outcomes
- Chronic Lymphocytic Leukemia Research
- Traumatic Brain Injury Research
- Nutrition, Genetics, and Disease
- Empathy and Medical Education
- Cancer, Stress, Anesthesia, and Immune Response
The University of Texas Health Science Center at Houston
2017-2024
U.S. Army Center for Health Promotion and Preventive Medicine
2024
University Physicians
2023
The University of Texas Health Science Center at San Antonio
2016-2018
Mays Cancer Center at UT Health San Antonio
2018
The University of Texas at San Antonio
2018
University of Calgary
2012
Duke University Hospital
2011
Duke Medical Center
2011
Guy's Hospital
2005
Pralatrexate is a rationally designed antifolate with greater preclinical antitumor activity than methotrexate. was synergistic paclitaxel and docetaxel in mouse xenograft experiments. This phase 1 study to determine the maximum tolerated dose toxicity of pralatrexate plus or patients advanced cancer.Pralatrexate administered i.v. every 2 weeks (days 15) 4-week cycle. Depending on taxane used being tested, days 15; 16; 1, 8, 15. In latter part study, arm were treated vitamin B(12) folic acid...
Research in palliative care demonstrates improvements overall survival, quality of life, symptom management, and reductions the cost care. Despite American Society Clinical Oncology recommendation for early concurrent patients with advanced cancer high burden, integrating services is challenging. Our aims were to quantitatively describe referral rates burden a South Texas center establish system by implementing Edmonton Symptom Assessment Scale (ESAS).
Background: The American Society of Clinical Oncology's recommendation for "dedicated palliative care services, early in the disease course, concurrent with active treatment" cancer patients is a challenge centers to accommodate. Despite demonstrated benefits care, disparities among socioeconomic and ethnic groups access supportive services have been described. aim this project was evaluate: a) how insurance coverage ethnicity impact patient symptom burden and, b) those factors influence at...
This study evaluated two automated external defibrillators (AEDs) to determine the extent which different AED designs affect performance of older adults over age 65 years. Forty-two untrained laypersons (20 young adults, M = 27 years old and 22 71 old) were randomly assigned use training versions either Medtronic LifePak CR Plus or Zoll during a simulated cardiac arrest using an iStan patient simulator. A number aspects difficult for groups. Fifty percent users 55% younger able AEDs deliver...
Abstract Introduction: Disparities in cancer care patients from different races and ethnicities unfortunately do exist are well described literature. Hormonal-driven cancers, such as some soft-tissue tumors DCIS, have been demonstrated to impact African-American women (AAW) disproportionately. These at increased risk for not only development of these but also experience disparities survival, treatment outcomes, modalities treatment. Clinical Case: A 47-year-old premenopausal AAW with past...
Abstract Introduction and objectives: The incidence of breast cancer (BC) in younger women has increased recent years, raising the discussion on adjustments to screening recommendations. This past May, a new draft recommendation USPSTF guidelines for BC adjusted age from 50 40. However, there is still insufficient evidence recommend patients at risk including ethnic minorities with higher mortality dense breasts. paucity trials reviews many these at-risk groups may be leading later diagnosis...
Abstract Background Multifocal (MF) multicentric breast cancer is a form of that consists disease independently developing at various locations due to tumor clone spreading within the ductal complex. associated with increased local recurrence. Our case highlights an example multifocal and addresses treatment challenges. Case presentation The patient 52-year-old African American female history HCV cirrhosis, diabetes mellitus, hypertension who presented palpable 4 cm right mass, without...
Permethrin-treated clothing is often recommended as a first line of defense against tick-borne diseases. In 2012, the permethrin factory-treated Army Combat Uniform was made available to active duty Soldiers, National Guard, Reserve Enlisted and Senior/Junior Officers Training Corps. Subsequently, Air Force Marine Corps personnel were also offered uniforms. Here, we use passive surveillance data collected through Military Tick Identification/Infection Confirmation Kit (MilTICK) program...
For the estimated 10 million women in United States who meet high-risk criteria for breast cancer, evidence-based interventions may reduce risk of cancer by 50-65%. Even with substantial evidence supporting preventive medication reduction, there is significant lack uptake and adherence. The purpose this study was to characterize experience at high define content domain a patient-reported outcomes (PRO) measure symptom burden from reducing medication. Thirty receiving participated single...
130 Background: Palliative medicine is dedicated to improving quality of life for patients throughout their disease course. The integration palliative in oncology practice has increased due growing evidence benefits patient. While the collaboration and care beneficial, access services remains an issue cancer patients. aim this project evaluate how insurance status impacts South Texas. Methods: During a 5-month study period, 607 from medical clinics were evaluated based on Edmonton Symptom...
e18233 Background: Timeliness of cancer treatment is an important aspect health care quality. Colorectal (CRC) requires the coordinated multidisciplinary effort various aspects system, which can lead to delays between initial diagnoses definitive therapy. Little known about time from diagnosis cancer-directed treatment, neither factors that cause or its effect on patient outcomes. Delays curative surgery beyond 12 weeks are associated with increased mortality in CRC. Longer adjuvant...
Abstract Aims: While women with breast cancer may have increased survival when compared to other cancers, aggressive, multi-modal treatments are often required significant impact on quality of life and economic cost, highlighting the importance prevention screening. For estimated 10 million in United States who meet high-risk criteria for cancer, evidence-based interventions be implemented reduce risk, including long-term chemoprevention. Engaging preventative care requires a healthy woman...
Abstract Background: Women with breast cancer account for the largest cohort (23%) of over 18 million survivors in United States. Of nearly 4 survivors, many, including individuals metastatic cancer, will require lifelong treatment chronic conditions. As part a multi-site study diverse tumor types, are being recruited to explore feasibility and outcomes digital health coaching (DHC) program following completion primary therapy support self-management symptoms general wellness. Trial design:...
TPS12141 Background: The landscape for cancer survivors continues to evolve as individuals live longer following primary therapy. For some, treatment is complete; others, active surveillance or maintenance therapy may be indicated. Individual survivorship needs are diverse, influenced by tumor and type, well social determinants of health. Digital interventions support in achieving personalized health goals throughout survivorship. Comprehensive Outcomes After Cancer Health (COACH) Study...
232 Background: Research has established that woman with a history of lymphoma who receive chest wall radiation are at greater risk to develop breast cancer. As such, recommendations for cancer screening received prior RT < 30yr age have been topic discussions the better part 20 ears. Survivorship programs our successfully treated hematologic malignancies should include referring survivors given their substantially increased treatment related Methods: We investigated 88 patients had by...
8 Background: The financial cost of cancer is a large burden and continues to rise substantially. Expenditures can be divided into the initial phase after diagnosis, continuing phase, last year life. Typically costs are greatest in major determinant during hospitalizations. We sought examine patients with newly diagnosed malignancies at an academic institution compare outcomes based on insurance status. Our serves significant portion South Texas, population facing serious health disparities....
178 Background: Timeliness of cancer treatment is an important aspect health care quality. Colorectal (CRC) requires the coordinated multidisciplinary effort various aspects system, which can lead to delays between initial diagnoses definitive therapy. Little known about time from diagnosis cancer-directed treatment, neither factors that cause or its effect on patient outcomes. Delays curative surgery beyond 12 weeks are associated with increased mortality in CRC. Longer adjuvant...
72 Background: Hematologic malignancies (HM) such as leukemias, lymphomas, and myeloma are potentially curable or may have long lasting remission with current therapy. While therapy prolong life even in an incurable setting, treatments for relapsed refractory disease many hematological fail a substantial number of patients HM terminally ill. Hospice care services notably underutilized HM. Methods: We performed retrospective cohort analysis 22 treated from 2013-2016 terminal Using adapted...