- Cancer survivorship and care
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Effects of Radiation Exposure
- Cancer-related cognitive impairment studies
- Childhood Cancer Survivors' Quality of Life
- Exercise and Physiological Responses
- Musculoskeletal pain and rehabilitation
- Tryptophan and brain disorders
- Brain Metastases and Treatment
- Cancer, Hypoxia, and Metabolism
- Nutrition and Health in Aging
- Cancer, Stress, Anesthesia, and Immune Response
- Stress Responses and Cortisol
- Glioma Diagnosis and Treatment
- Bioinformatics and Genomic Networks
- Histone Deacetylase Inhibitors Research
- Pain Mechanisms and Treatments
- Psychosomatic Disorders and Their Treatments
- Complementary and Alternative Medicine Studies
- Mitochondrial Function and Pathology
- Nerve injury and regeneration
- Health, psychology, and well-being
- Cancer Treatment and Pharmacology
- Frailty in Older Adults
- Management of metastatic bone disease
National Institutes of Health
2016-2025
National Institute of Nursing Research
2016-2025
Office of Extramural Research
2018-2024
Federal Reserve
2024
Amsterdam University Medical Centers
2023
Amsterdam UMC Location Vrije Universiteit Amsterdam
2023
Case Western Reserve University
2023
University School
2023
United States Department of Health and Human Services
2020-2021
National Institute of Health
2020
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype poorly defined, pathophysiology unknown, and no disease-modifying treatments are available. We used rigorous criteria to recruit PI-ME/CFS participants with matched controls conduct deep phenotyping. Among many physical cognitive complaints, one defining feature of was an alteration effort preference, rather than or central fatigue, due dysfunction integrative...
Cancer-related fatigue (CRF) is associated with negative health outcomes and decreased health-related quality of life; however, few longitudinal studies have investigated molecular-genetic mechanisms CRF.
Breast cancer survivors (BCS) often complain of cancer-related cognitive impairment (CRCI) during and even months after completing primary treatments, particularly chemotherapy. The etiology CRCI is unknown, but associations with germline genetic polymorphisms have been reported, including Brain-Derived Neurotrophic Factor (BDNF) rs6265 polymorphism. current study investigated the specific BDNF CRCI.
Fatigue is a common side effect of cancer (CA) treatment. We used novel analytical method to identify and validate specific gene cluster that predictive fatigue risk in prostate patients (PCP) treated with radiotherapy (RT).A total 44 PCP were categorized into high-fatigue (HF) low-fatigue (LF) cohorts based on score change from baseline RT completion. Fold-change differential Fisher's linear discriminant analyses (LDA) 27 subjects expression data at completion generated reduced base most...
The mechanisms underlying the transition from acute to chronic pain remain unclear. Here, we sought characterize transcriptome associated with low back as well of pain. For analysis, compared whole blood of: (a) patients at onset who no longer had within 6 weeks after (acute) developed months (chronic T5); and, (b) T1) healthy pain-free (normal) controls. majority differentially expressed genes were protein coding. We illustrate a unique characterized by significant enrichment for known...
Anxiety is one of the psychological problems being experienced by general population during current coronavirus disease 2019 (COVID-19) pandemic. Health literacy, such as infectious-disease-specific health associated with anxiety, but mechanism association not clear. This study explored relationship between literacy and anxiety.We conducted an online survey in Hubei province, early epicenter COVID-19 A total 1038 COVID-19-negative participants accomplished a battery tools determining their...
Fatigue is one of the most common side-effects accompanying radiotherapy, but arguably least understood. Radiotherapy-induced fatigue (RIF) a clinical subtype cancer treatment-related fatigue. It described as pervasive, subjective sense tiredness persisting over time, interferes with activities daily living, and not relieved by adequate rest or sleep. RIF early long-lasting for patients treated localized radiation. Although underlying mechanisms have been studied in several disease...