A5102219453- Menopause: Health Impacts and Treatments
- Ovarian function and disorders
- Phytoestrogen effects and research
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Estrogen and related hormone effects
- Acupuncture Treatment Research Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Medicinal Plant Pharmacodynamics Research
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Sexual function and dysfunction studies
- Menstrual Health and Disorders
- RNA modifications and cancer
- Diet and metabolism studies
- Endometriosis Research and Treatment
- Pharmacological Effects of Natural Compounds
- Pelvic floor disorders treatments
- Uterine Myomas and Treatments
- Psychosomatic Disorders and Their Treatments
- Redox biology and oxidative stress
- Genomics, phytochemicals, and oxidative stress
- Medical Research and Treatments
- Cancer-related cognitive impairment studies
- Ferroptosis and cancer prognosis
Shanghai University of Traditional Chinese Medicine
2006-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2015-2025
University Medical Center Hamburg-Eppendorf
2011-2012
Universität Hamburg
2011-2012
Yueyang Hospital
2011-2012
Heilongjiang Provincial Academy of Agricultural Sciences
2011
Shuguang Hospital
2006
Cervical cancer is the fourth most common in women globally, and main cause of disease has been found to be ongoing HPV infection. remains primary cancer-related death despite major improvements screening treatment approaches, especially low- middle-income nations. Therefore, it crucial investigate tumor microenvironment advanced cervical order identify possible targets. In better understand malignant epithelial cells (EPCs), this study used bulk RNA-seq data from UCSC conjunction with...
People with mild cognitive impairment (MCI) carry a considerable risk of developing dementia. Studies have shown that female sex hormones long-lasting neuroprotective and anti-aging properties, the increased MCI AD is associated lack estrogen during menopause. Previous studies Tiao Geng Decoction (TGD) may antioxidant anti apoptotic which prevent neurodegenerative diseases. However, whether TGD effective in improving due to postmenopausal deficiency its potential pharmacological mechanisms...
Paeoniflorin (PF) exerts a significant protective effect against neurotoxicity and mitochondrial damage in neurons. However, the mechanisms underlying PF-mediated rescue remain elusive. Therefore, we endeavored to further research molecular inhibition of tributyltin chloride (TBTC)-induced apoptosis neurons.To investigate influence possible mechanism action PF TBTC-induced neurodegenerative disease.First, primary hypothalamic neurons were treated with (150 μg/L) (25, 50, 100 μM)....
Herb mixtures are widely used as an alternative to hormonal therapy in China for treatment of the menopausal syndrome. However, composition these herb complex and their working mechanism is often unknown. This study investigated effect Tiáo-Gēng-Tāng (TG-decoction), a Chinese herbal mixture extract, balancing female hormones, regulating expression estrogen receptors (ERs), preventing aging-related tissue damage. Ovariectomized 5-month-old rats were model menopause treated with either...
Endometriosis (EMs) is a common chronic inflammatory disease which characterized by multiple clinical symptoms and high recurrence rate due to the absence of effective therapies. Huayu Jiedu Formula (HYJDF), traditional Chinese medicine prescription with five major herbs. It has been used as treat EMs for more than twenty years exerted good therapeutic effect. However, underlying mechanism unclear. Here we aim observe effects HYJDF on investigate mechanism.
Tiao Geng (TG) decoction is a Chinese herbal medicine extract that has been utilized for the treatment of menopausal symptoms history over 30 years. In our previous study, we suggest TG possibly exerts an anti-apoptotic effect on hypothalamic neurons ovariectomized rats via ASK1/MKK7/JNK pathway. Tributyltin chloride (TBTC) causes oxidative damage and induces apoptosis primary in rats. The present work aimed to explore inhibition TBTC-induced GT1-7 cell its possible molecular mechanism. line...
Tiaogeng decoction (TGD), a mixture of 10 traditional Chinese herbs, has been used clinically for over 30 years in treating menopause-related symptoms such as cognitive changes, mood disorders, vasomotor symptoms, and sleep disorders. These central nervous system are closely associated with declined ovarian function, which dramatically increases the risk neurodegenerative disease. Previous studies revealed that TGD may have anti-oxidative anti-apoptotic properties, potentially preventing...
TG-decoction (Tiao Geng decoction) is the extract of a Chinese herb mixture that has been used for treating menopausal symptoms over 30 years. We have previously reported anti-aging and anti-oxidative effects on hypothalamic neurons in ovariectomized (OVX) rats. Aim study: The present study further investigates prevention aging-related ultrastructural changes likely molecular mechanism. A total 120 four-month-old female SPF Sprague Dawley rats were divided into six groups. Five groups one...
To observe the effects of electroacupuncture (EA) on ovarian reaction, egg and embryo quality, as well pregnancy rate in poor response (POR) patients kidney essence deficiency undergoing vitro fertilization-embryo transfer (IVF-ET).Ninety-six who met inclusion criteria were randomly divided into an EA group a control group, with 48 cases each group. Before IVF-ET, received EA, once daily, 2 or 3 treatments week for 12 weeks. after treatment, traditional Chinese medicine (TCM) syndrome score...