A5075217351- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Inflammatory Bowel Disease
- Genomics, phytochemicals, and oxidative stress
- IL-33, ST2, and ILC Pathways
- Gut microbiota and health
- Muscle metabolism and nutrition
- Diet, Metabolism, and Disease
- Nigella sativa pharmacological applications
- Probiotics and Fermented Foods
- Bioactive Compounds and Antitumor Agents
- Ethics in medical practice
- Dietary Effects on Health
- Exercise and Physiological Responses
- Hydrogen's biological and therapeutic effects
- Infant Nutrition and Health
- Reproductive System and Pregnancy
- Regulation of Appetite and Obesity
- Antioxidants, Aging, Portulaca oleracea
- Nutrition, Genetics, and Disease
- Medical Malpractice and Liability Issues
University of Maine
2023
Ursinus College
2019-2022
Previous studies suggest that sex differences in lipid metabolism exist with females demonstrating a higher utilization of lipids during exercise, which is mediated partly by increased muscle triglycerides. However, whether these changes contribute directly to endurance exercise performance unclear. Therefore, the objective this study was investigate contribution substrate capacity (EEC) mice. Male and female C57BL/6-NCrl mice were subjected an EEC test until exhaustion on motorized...
Evaluating bacterial communities across different locations in the gut provides a greater insight than fecal samples alone and an additional metric by which to evaluate beneficial host-microbe interactions. Here, we show that 10% steamed broccoli sprouts diet protects mice from negative effects of dextran sodium sulfate-induced colitis, colitis erases biogeographic patterns gut, cecum is not likely be significant contributor colonic bacteria interest DSS mouse model ulcerative colitis. Mice...
To our knowledge, IL-10-KO mice have not previously been used to investigate the interactions of host, microbiota, and broccoli, broccoli sprouts, or bioactives in resolving symptoms CD. We showed that a diet containing 10% raw sprouts increased plasma concentration anti-inflammatory compound sulforaphane protected varying degrees against disease symptoms, including weight loss stagnation, fecal blood, diarrhea. Younger responded more strongly diet, further reducing as well gut bacterial...
The promotion of ketone body (KB) metabolism via ketosis has been suggested as a strategy to increase exercise performance. However, studies in humans and animals have yielded inconsistent results. purpose the current study was examine effects ketosis, achieved fasting or short-term ketogenic diet (KD), on endurance performance female mice. After 8 h fasting, serum KB significantly increased glucose decreased fasted compared fed When subjected an capacity (EEC) test motorized treadmill, both...
Abstract Crohn’s Disease (CD) is a presentation of Inflammatory Bowel (IBD) that manifests in childhood and adolescence, involves chronic severe enterocolitis, immune gut microbiome dysregulation, other complications. Diet gut-microbiota-produced metabolites are sources anti-inflammatories which could ameliorate symptoms. However, questions remain on how IBD influences biogeographic patterns microbial location function the gut, early life transitional communities affected by diet...
Inflammatory Bowel Diseases (IBD) are devastating conditions of the gastrointestinal tract with limited treatments, and dietary intervention may be effective, affordable, for managing symptoms. Glucosinolate compounds highly concentrated in broccoli sprouts, especially glucoraphanin, can metabolized by certain mammalian gut bacteria into anti inflammatory isothiocyanates, such as sulforaphane. Gut microbiota exhibit biogeographic patterns, but it is unknown if colitis alters these or whether...