A5102739481- Parkinson's Disease Mechanisms and Treatments
- DNA Repair Mechanisms
- Fungal and yeast genetics research
- Signaling Pathways in Disease
- Genetic Neurodegenerative Diseases
- Cholinesterase and Neurodegenerative Diseases
University of Gothenburg
2024
Chalmers University of Technology
2024
The University of Texas Southwestern Medical Center
2024
Institute for Biomedicine
2024
A major consequence of aging and stress, in yeast to humans, is an increased accumulation protein aggregates at distinct sites within the cells. Using genetic screens, immunoelectron microscopy, three-dimensional modeling our efforts elucidate importance aggregate annexation, we found that most accumulate near surface mitochondria. Further, show virus-like particles (VLPs), which are part retrotransposition cycle Ty elements, markedly enriched these aggregation. RNA interference-mediated...
Institute for Biomedicine, Sahlgrenska Academy, Centre Ageing and Health – AgeCap, University of Gothenburg, Sweden Department Life Sciences, Chalmers Technology, *Correspondence to: Srishti Chawla, PhD, [email protected] or This is an open-access article distributed under the terms Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, reproduction in any medium, provided original work properly cited.