A5061937136- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neurogenetic and Muscular Disorders Research
- Muscle Physiology and Disorders
- Infant Development and Preterm Care
- Retinoids in leukemia and cellular processes
- Neonatal and fetal brain pathology
- Amyotrophic Lateral Sclerosis Research
- Prenatal Substance Exposure Effects
- Childhood Cancer Survivors' Quality of Life
- Spinal Dysraphism and Malformations
- Infectious Diseases and Tuberculosis
- Genetics and Neurodevelopmental Disorders
- Bacterial Infections and Vaccines
- Ion channel regulation and function
- Hemoglobinopathies and Related Disorders
- Infectious Encephalopathies and Encephalitis
- Maternal Mental Health During Pregnancy and Postpartum
- Autoimmune Neurological Disorders and Treatments
- Mechanical Circulatory Support Devices
- Language Development and Disorders
- Cerebral Palsy and Movement Disorders
- Folate and B Vitamins Research
- Teratomas and Epidermoid Cysts
- Fetal and Pediatric Neurological Disorders
University of Saskatchewan
2014-2023
Qatif Central Hospital
2020
Royal University Hospital
2020
Stollery Children's Hospital
2012
University of Alberta
2011
Importance Health-related quality of life (HRQOL) is regarded as a key outcome for evaluating treatment efficacy. However, it uncertain how HRQOL evolves after epilepsy surgery compared with medical therapy, such whether continues to improve over time, improves and then remains stable, or deteriorates period time. Objective To assess trajectory 2 years in children drug-resistant (DRE) treated therapy. Design, Setting, Participants Prospective cohort study assessing longitudinally years. were...
We report the recruitment activities and outcomes of a multi-disease neuromuscular patient registry in Canada. The Canadian Neuromuscular Disease Registry (CNDR) registers individuals across Canada with confirmed diagnosis disease. Diagnosis contact information are collected all diseases detailed prospective data is for 5 specific diseases: Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), Myotonic (DM), Limb Girdle (LGMD), Spinal Atrophy (SMA). Since 2010, CNDR has...
Abstract Objectives The purpose of this longitudinal cohort study was to examine the variables that influence health‐related quality life (HRQOL) after epilepsy surgery in children. We examined whether treatment type (surgical vs medical therapy) and seizure control are related other have been shown HRQOL, namely depressive symptoms children with or their parents, availability family resources. Methods In total, 265 drug‐resistant were recruited from eight centers across Canada at time...
Spinal muscular atrophy (SMA) is a devastating rare disease that affects individuals regardless of ethnicity, gender, and age. The first-approved disease-modifying therapy for SMA, nusinursen, was approved by Health Canada, as well American European regulatory agencies following positive clinical trial outcomes. trials were conducted in narrow pediatric population defined age, severity, genotype. Broad approval necessitates close follow-up potential adverse events effectiveness the larger...
Prenatal alcohol exposure is a cause of congenital brain malformations such as hydrocephalus; however, complete mechanism accounting for this phenomenon has yet to be discovered. We report case newborn who was exposed throughout pregnancy and presented with low serum vitamin A hydrocephalus. To our knowledge, the connection between prenatal ethanol exposure, deficiency, developmental anomaly never been described in humans before. possible may mediated by disruption homeostasis A, an...
This longitudinal cohort study aimed to identify trajectories of parent well-being over the first 2 years after their child's evaluation for candidacy epilepsy surgery, and baseline clinical demographic characteristics associated with these trajectories. Parent was based on depressive anxiety symptoms family resources (i.e., mastery social support).Parents 259 children drug-resistant (105 whom eventually had surgery) were recruited from eight centers across Canada at time surgery candidacy....
Basal ganglia injury, accompanied by extrapyramidal signs, has been described in the setting of chronic tuberculous meningitis; however, such injury rarely occurs acute bacterial meningitis and never reported with meningococcal meningitis. We report case a boy who developed tongue bradykinesia dysarthria 1 week following presentation Magnetic resonance imaging revealed bilateral basal lesions, suspected to result from cytotoxic edema secondary infection. The patient subsequently general...