A5064814132- Genetic and phenotypic traits in livestock
- Veterinary Equine Medical Research
- Ruminant Nutrition and Digestive Physiology
- Effects of Environmental Stressors on Livestock
- Muscle metabolism and nutrition
- Meat and Animal Product Quality
- Liver Disease Diagnosis and Treatment
- Physiological and biochemical adaptations
- Fisheries and Aquaculture Studies
- Genetic Associations and Epidemiology
- Animal Behavior and Welfare Studies
- Genetic diversity and population structure
- Fish Biology and Ecology Studies
- Biomedical Ethics and Regulation
- Sodium Intake and Health
- Agriculture Sustainability and Environmental Impact
- Plant Toxicity and Pharmacological Properties
- Climate Change and Health Impacts
- Noise Effects and Management
- Folate and B Vitamins Research
- Plant and fungal interactions
- Agricultural Economics and Practices
- Telomeres, Telomerase, and Senescence
- Genetics and Physical Performance
- Silkworms and Sericulture Research
Massachusetts General Hospital
2024-2025
University of Louisville
2020
University of Nebraska–Lincoln
2014
Virginia Tech
2009-2011
BACKGROUND: Cardiovascular disease (CVD) risk differs across Asian subgroups, possibly due to differences in hypertension burden. We characterized lifetime blood pressure (BP) trajectories for East and South individuals compared their associations with CVD risk. METHODS: Among 148 872 UK Biobank participants primary care utilization data, life course BP were fitted as a function of age by sex according self-identified ethnicity. determined time-averaged young adulthood (18–39 years), middle...
Abstract Leukocyte telomere length (LTL) is associated with multiple conditions, including cardiovascular diseases and neoplasms, yet their differential associations across diverse individuals are largely unknown. We estimated LTL from blood-derived whole genome sequences in the All of Us Research Program (n=242,494) backgrounds United States. was lifestyle, socioeconomic status, biomarkers, cardiometabolic diseases, neoplasms heterogeneity genetic ancestries sexes. Geographical analysis...
Pedigrees of a reference population 1 659 North American Norwegian Fjord horses were traced to founders and analysed for coefficients inbreeding genetic variability. Effective size was 207.8 there 641 total founders. Pedigree completeness close 100 percent 6 generations, with 9.8 average complete generation equivalents. The coefficient 3.2 the entire pedigree 1.6 pedigrees back five generations. Average by year birth increased until 1983, before decreasing then stabilizing through 2009....
Divergent selection for heat loss was implemented in mice creating maintenance high (MH) and low (ML) lines an unselected control (MC) 3 independent replicates. Mice from the ML line have improved feed efficiency, due to decreased energy requirement, but there is potential a correlated decline reproductive performance survivability. Number fully formed (NFF), number born alive (NBA), weaned (NW), litter weaning weight (LWW), pup (PWW), fraction at birth (FAB), weaning, interval were recorded...
Changes in maintenance energy requirements and feed efficiency have been achieved by divergent selection for heat loss mice 3 replicates, creating high loss, (MH) low (ML) lines an unselected control (MC). However, intake has mainly measured mature animals not during growth or reproduction. Additionally, there is evidence that reducing will increase fat content, undesirable result. To evaluate if altered body composition lifecycle intake, mating pairs were continuously mated maintained up to...
Abstract Rare coding alleles play crucial roles in the molecular diagnosis of genetic diseases. However, systemic identification these has been challenging due to their scarcity general population. Here, we discovered and characterized rare contributing dyslipidemia, a principal risk for coronary artery disease, among over million individuals combining three large contemporary datasets (the Million Veteran Program, n = 634,535, UK Biobank, 431,178, All Us Research 92,304) totaling 1,158,017...
Introduction: South Asians living in the United States (SAUS) experience greater cardiovascular disease (CVD) events compared to most other racial and ethnic groups. Limited representation collection of relevant community-specific identity, health, lifestyle, exposure factors studies date have impeded understanding this elevated risk. To address these scientific gaps, OurHealth study was devised as a scalable national biobank SAUS populated with demographic, genetic data. Aims: The primary...
Divergent selection in mice for heat loss was conducted 3 independent replicates creating a high maintenance, (MH) and low (ML) line unselected control (MC). Improvement feed efficiency observed ML due to reduced maintenance energy requirement but there also slight decline reproductive performance, survivability, lean content, particularly when compared MC animals. The objective of this study model life cycle scenario similar livestock production system calculate total inputs outputs...
Background: Several epidemiological studies report that residential proximity to greenness is associated with positive health benefits. However, it unclear whether such associations vary ecology and the type of vegetation. Therefore, we investigated between mortality by ecology, as categorized EPA ecoregions. Methods: County level data from 2010 in contiguous United States (n=2,733) were analyzed using linear regression determine was log-transformed age-adjusted all-cause cardiovascular...